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The serum uric acid and related cardiovascular risk factors in south Taiwan.

Abstract

Hyperuricemia has been shown to be related to cardiovascular morbidity and mortality. Uric acid is a metabolic product synthesized from nucleic acids, amino acids and the Krebs cycle, reflecting a multiple metabolic associations in humans. The relation between uric acid and various cardiovascular metabolic parameters in Asians has rarely been reported on. In this study, we report the relationship between uric acid and various cardiovascular risk factors in 1,027 healthy Taiwanese adults living in Alien, an agricultural town in subtropical South Taiwan. Serum uric acid levels increased in proportion to age in women, but not in men. There were age and gender-specific correlations between uric acid and various cardiovascular metabolic parameters. Triglycerides and creatinine levels were two independent factors predicting serum uric acid levels in men, while only creatinine predicted uric acid levels in women of all age groups. Processes that influence the metabolism of uric acid and its association with other metabolic parameters differs by gender and age.

Authors+Show Affiliations

Department of Neurology, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15906680

Citation

Huang, Chih-Cheng, et al. "The Serum Uric Acid and Related Cardiovascular Risk Factors in South Taiwan." The Southeast Asian Journal of Tropical Medicine and Public Health, vol. 36, no. 1, 2005, pp. 259-64.
Huang CC, Peng MC, Tsai WC, et al. The serum uric acid and related cardiovascular risk factors in south Taiwan. Southeast Asian J Trop Med Public Health. 2005;36(1):259-64.
Huang, C. C., Peng, M. C., Tsai, W. C., Chang, Y. Y., Chen, W. H., Chen, S. S., & Liu, J. S. (2005). The serum uric acid and related cardiovascular risk factors in south Taiwan. The Southeast Asian Journal of Tropical Medicine and Public Health, 36(1), pp. 259-64.
Huang CC, et al. The Serum Uric Acid and Related Cardiovascular Risk Factors in South Taiwan. Southeast Asian J Trop Med Public Health. 2005;36(1):259-64. PubMed PMID: 15906680.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The serum uric acid and related cardiovascular risk factors in south Taiwan. AU - Huang,Chih-Cheng, AU - Peng,Ming-Chao, AU - Tsai,Wen-Chung, AU - Chang,Yung-Yee, AU - Chen,Wei-Hsi, AU - Chen,Shun-Sheng, AU - Liu,Jia-Shou, PY - 2005/5/24/pubmed PY - 2005/8/23/medline PY - 2005/5/24/entrez SP - 259 EP - 64 JF - The Southeast Asian journal of tropical medicine and public health JO - Southeast Asian J. Trop. Med. Public Health VL - 36 IS - 1 N2 - Hyperuricemia has been shown to be related to cardiovascular morbidity and mortality. Uric acid is a metabolic product synthesized from nucleic acids, amino acids and the Krebs cycle, reflecting a multiple metabolic associations in humans. The relation between uric acid and various cardiovascular metabolic parameters in Asians has rarely been reported on. In this study, we report the relationship between uric acid and various cardiovascular risk factors in 1,027 healthy Taiwanese adults living in Alien, an agricultural town in subtropical South Taiwan. Serum uric acid levels increased in proportion to age in women, but not in men. There were age and gender-specific correlations between uric acid and various cardiovascular metabolic parameters. Triglycerides and creatinine levels were two independent factors predicting serum uric acid levels in men, while only creatinine predicted uric acid levels in women of all age groups. Processes that influence the metabolism of uric acid and its association with other metabolic parameters differs by gender and age. SN - 0125-1562 UR - https://www.unboundmedicine.com/medline/citation/15906680/The_serum_uric_acid_and_related_cardiovascular_risk_factors_in_south_Taiwan_ DB - PRIME DP - Unbound Medicine ER -