Tags

Type your tag names separated by a space and hit enter

Prenylated anthronoid antioxidants from the stem bark of Harungana madagascariensis.
Phytochemistry. 2005 May; 66(10):1174-9.P

Abstract

Two new prenylated anthronoids, harunmadagascarins A and B, were isolated from the stem bark of Harungana madagascariensis along with six known compounds including two anthronoids: harunganol B and harungin anthrone, one benzophenone: methyl 3-formyl-2,4-dihydroxy-6-methyl benzoate and three pentacyclic triterpenes: friedelin, lupeol and betulinic acid. Harunmadagascarins A and B were characterized as 8,9-dihydroxy-4,4-bis-(3,3-dimethylallyl)-6-methyl-2,3-(2,2-dimethylpyrano)anthrone and 8,9-dihydroxy-4,4,5-tris-(3,3-dimethylallyl)-6-methyl-2,3-(2,2-dimethylpyrano)anthrone, respectively. The structures of these secondary metabolites were determined by spectroscopic means and comparison with the published data. Methyl 3-formyl-2,4-dihydroxy-6-methyl benzoate was isolated for the first time from a plant. Harunmadagascarins A and B, harunganol B and harungin anthrone exhibited significant antioxidant activity.

Authors+Show Affiliations

Kouam SF
Department of Chemistry, Higher Teachers' Training College, University of Yaounde 1, BP 47, Yaounde, Cameroon.
Ngadjui BT
No affiliation info available
Krohn K
No affiliation info available
Wafo P
No affiliation info available
Ajaz A
No affiliation info available
Choudhary MI
No affiliation info available

MeSH

AnthracenesAntioxidantsClusiaceaeFree Radical ScavengersMolecular StructurePlant BarkPlant Stems

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15924922

Citation

Kouam, Simeon F., et al. "Prenylated Anthronoid Antioxidants From the Stem Bark of Harungana Madagascariensis." Phytochemistry, vol. 66, no. 10, 2005, pp. 1174-9.
Kouam SF, Ngadjui BT, Krohn K, et al. Prenylated anthronoid antioxidants from the stem bark of Harungana madagascariensis. Phytochemistry. 2005;66(10):1174-9.
Kouam, S. F., Ngadjui, B. T., Krohn, K., Wafo, P., Ajaz, A., & Choudhary, M. I. (2005). Prenylated anthronoid antioxidants from the stem bark of Harungana madagascariensis. Phytochemistry, 66(10), 1174-9.
Kouam SF, et al. Prenylated Anthronoid Antioxidants From the Stem Bark of Harungana Madagascariensis. Phytochemistry. 2005;66(10):1174-9. PubMed PMID: 15924922.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prenylated anthronoid antioxidants from the stem bark of Harungana madagascariensis. AU - Kouam,Simeon F, AU - Ngadjui,Bonaventure T, AU - Krohn,Karsten, AU - Wafo,Pascal, AU - Ajaz,Asma, AU - Choudhary,M Iqbal, PY - 2004/12/08/received PY - 2005/03/15/revised PY - 2005/03/16/accepted PY - 2005/6/1/pubmed PY - 2005/8/20/medline PY - 2005/6/1/entrez SP - 1174 EP - 9 JF - Phytochemistry JO - Phytochemistry VL - 66 IS - 10 N2 - Two new prenylated anthronoids, harunmadagascarins A and B, were isolated from the stem bark of Harungana madagascariensis along with six known compounds including two anthronoids: harunganol B and harungin anthrone, one benzophenone: methyl 3-formyl-2,4-dihydroxy-6-methyl benzoate and three pentacyclic triterpenes: friedelin, lupeol and betulinic acid. Harunmadagascarins A and B were characterized as 8,9-dihydroxy-4,4-bis-(3,3-dimethylallyl)-6-methyl-2,3-(2,2-dimethylpyrano)anthrone and 8,9-dihydroxy-4,4,5-tris-(3,3-dimethylallyl)-6-methyl-2,3-(2,2-dimethylpyrano)anthrone, respectively. The structures of these secondary metabolites were determined by spectroscopic means and comparison with the published data. Methyl 3-formyl-2,4-dihydroxy-6-methyl benzoate was isolated for the first time from a plant. Harunmadagascarins A and B, harunganol B and harungin anthrone exhibited significant antioxidant activity. SN - 0031-9422 UR - https://www.unboundmedicine.com/medline/citation/15924922/Prenylated_anthronoid_antioxidants_from_the_stem_bark_of_Harungana_madagascariensis_ DB - PRIME DP - Unbound Medicine ER -