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Anti-inflammatory activity of Sapindus trifoliatus Linn.
J Herb Pharmacother. 2004; 4(4):43-50.JH

Abstract

Anti-inflammatory activity of the ethanolic extract of the seeds of Sapindus trifoliatus Linn. was studied in wister rats using the carrageenan induced left hind paw edema, carrageenan induced pleurisy and cotton pellet induced granuloma model. The ethanolic extract (150 mg/kg, p.o.) produced the inhibition of carrageenan induced rat paw edema. It also showed an inhibitory effect on leukocyte migration and a reduction on the pleural exudates as well as reduction on the granuloma weight in the cotton pellet granuloma method. The results indicated that the ethanolic extract produced significant (P < 0.001) anti-inflammatory activity when compared with the standard and untreated control.

Authors+Show Affiliations

Arul B
Department of Pharmaceutics, Vinayaka Mission's College of Pharmacy, Yercaud Main Road, Salem-636008, Tamil Nadu, India. arul1971@yahoo.com
Kothai R
No affiliation info available
Jacob P
No affiliation info available
Sangameswaran B
No affiliation info available
Sureshkumar K
No affiliation info available

MeSH

AnimalsAnti-Inflammatory AgentsCarrageenanDose-Response Relationship, DrugEdemaFoot DiseasesGranulomaInflammationLeukocyte CountMalePhytotherapyPlant ExtractsPleurisyRatsRats, WistarSapindus

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15927924

Citation

Arul, B, et al. "Anti-inflammatory Activity of Sapindus Trifoliatus Linn." Journal of Herbal Pharmacotherapy, vol. 4, no. 4, 2004, pp. 43-50.
Arul B, Kothai R, Jacob P, et al. Anti-inflammatory activity of Sapindus trifoliatus Linn. J Herb Pharmacother. 2004;4(4):43-50.
Arul, B., Kothai, R., Jacob, P., Sangameswaran, B., & Sureshkumar, K. (2004). Anti-inflammatory activity of Sapindus trifoliatus Linn. Journal of Herbal Pharmacotherapy, 4(4), 43-50.
Arul B, et al. Anti-inflammatory Activity of Sapindus Trifoliatus Linn. J Herb Pharmacother. 2004;4(4):43-50. PubMed PMID: 15927924.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anti-inflammatory activity of Sapindus trifoliatus Linn. AU - Arul,B, AU - Kothai,R, AU - Jacob,Philip, AU - Sangameswaran,B, AU - Sureshkumar,K, PY - 2005/6/2/pubmed PY - 2005/10/15/medline PY - 2005/6/2/entrez SP - 43 EP - 50 JF - Journal of herbal pharmacotherapy JO - J Herb Pharmacother VL - 4 IS - 4 N2 - Anti-inflammatory activity of the ethanolic extract of the seeds of Sapindus trifoliatus Linn. was studied in wister rats using the carrageenan induced left hind paw edema, carrageenan induced pleurisy and cotton pellet induced granuloma model. The ethanolic extract (150 mg/kg, p.o.) produced the inhibition of carrageenan induced rat paw edema. It also showed an inhibitory effect on leukocyte migration and a reduction on the pleural exudates as well as reduction on the granuloma weight in the cotton pellet granuloma method. The results indicated that the ethanolic extract produced significant (P < 0.001) anti-inflammatory activity when compared with the standard and untreated control. SN - 1522-8940 UR - https://www.unboundmedicine.com/medline/citation/15927924/Anti_inflammatory_activity_of_Sapindus_trifoliatus_Linn_ DB - PRIME DP - Unbound Medicine ER -