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[Antioxidative activity of some over-the-counter plant extracts].
Ceska Slov Farm. 2005 May; 54(3):114-7.CS

Abstract

The recent years again saw increased interest of the public in the use of traditional natural remedies, such as plant extracts, for the treatment and prevention of diseases. This paper evaluates the antioxidative activity and content of phenolic substances of selected plant extracts from medicinal herbs, sold as dietary supplements with therapeutic effects. Using the production of 3-nitrotyrosine as the marker, the effects of extracts on the inhibition of peroxynitrite-induced nitration of tyrosine was examined, and the results were compared with the ability to extinguish the stable radical 2,2-diphenyl-1-picrylhydrazyl (DPPH). A linear correlation (r = 0.929) was found between the ability to extinguish DPPH and to inhibit tyrosine nitration. The found antioxidative activity ranged between values of 0-1702, or 0-1482 micromol of the catechine equivalent/100 ml of the extract. The total content of phenolic substances oscillated within values of 9.4-268.3 mg of the equivalent of gallic acid/100 ml of the extract. The significant linear relationship between antioxidative activities (r>0.9) and the total content of phenolic substances shows that phenolic substances are the principal group responsible for the antioxidative activity of the extracts tested.

Authors+Show Affiliations

Veterinární a farmaceutická univerzita Brno, Farmaceutická fakulta, Ustav technologie léků. muselikj@vfu.czNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

cze

PubMed ID

15945457

Citation

Muselík, J, et al. "[Antioxidative Activity of some Over-the-counter Plant Extracts]." Ceska a Slovenska Farmacie : Casopis Ceske Farmaceuticke Spolecnosti a Slovenske Farmaceuticke Spolecnosti, vol. 54, no. 3, 2005, pp. 114-7.
Muselík J, Hytych P, Zemlicka M. [Antioxidative activity of some over-the-counter plant extracts]. Ceska Slov Farm. 2005;54(3):114-7.
Muselík, J., Hytych, P., & Zemlicka, M. (2005). [Antioxidative activity of some over-the-counter plant extracts]. Ceska a Slovenska Farmacie : Casopis Ceske Farmaceuticke Spolecnosti a Slovenske Farmaceuticke Spolecnosti, 54(3), 114-7.
Muselík J, Hytych P, Zemlicka M. [Antioxidative Activity of some Over-the-counter Plant Extracts]. Ceska Slov Farm. 2005;54(3):114-7. PubMed PMID: 15945457.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Antioxidative activity of some over-the-counter plant extracts]. AU - Muselík,J, AU - Hytych,P, AU - Zemlicka,M, PY - 2005/6/11/pubmed PY - 2005/10/28/medline PY - 2005/6/11/entrez SP - 114 EP - 7 JF - Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti JO - Ceska Slov Farm VL - 54 IS - 3 N2 - The recent years again saw increased interest of the public in the use of traditional natural remedies, such as plant extracts, for the treatment and prevention of diseases. This paper evaluates the antioxidative activity and content of phenolic substances of selected plant extracts from medicinal herbs, sold as dietary supplements with therapeutic effects. Using the production of 3-nitrotyrosine as the marker, the effects of extracts on the inhibition of peroxynitrite-induced nitration of tyrosine was examined, and the results were compared with the ability to extinguish the stable radical 2,2-diphenyl-1-picrylhydrazyl (DPPH). A linear correlation (r = 0.929) was found between the ability to extinguish DPPH and to inhibit tyrosine nitration. The found antioxidative activity ranged between values of 0-1702, or 0-1482 micromol of the catechine equivalent/100 ml of the extract. The total content of phenolic substances oscillated within values of 9.4-268.3 mg of the equivalent of gallic acid/100 ml of the extract. The significant linear relationship between antioxidative activities (r>0.9) and the total content of phenolic substances shows that phenolic substances are the principal group responsible for the antioxidative activity of the extracts tested. SN - 1210-7816 UR - https://www.unboundmedicine.com/medline/citation/15945457/[Antioxidative_activity_of_some_over_the_counter_plant_extracts]_ L2 - https://medlineplus.gov/antioxidants.html DB - PRIME DP - Unbound Medicine ER -
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