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Outbreak of methicillin-resistant Staphylococcus aureus in two nursing homes in Central Norway.
J Hosp Infect 2005; 60(4):312-6JH

Abstract

Until recently, infections with methicillin-resistant Staphylococcus aureus (MRSA) have mainly been associated with hospital outbreaks in Norway. However, increasingly cases are contracted outside hospitals. This paper reports the first two outbreaks of MRSA in two nursing homes in central Norway, affecting 23 residents and five staff members. Pulsed-field gel electrophoresis analysis showed that all strains from nursing home A were identical and that the strains from nursing home B were genotypically similar with one or two band differences. Multi-locus sequence typing (MLST) showed that the strains from the two nursing homes belong to clonal complex 45, with each strain being a single-locus variant of sequence type 45 (ST 45), a well-known European epidemic strain. No evident source of the two outbreaks was found, and there was no obvious connection between the two outbreaks. The latter is also supported by the minor differences observed by MLST, suggesting a connection at some time in the past. The outbreaks led to a heavier workload and economic strain on both nursing homes. The outbreak in nursing home A was brought to an end, whereas two residents remained colonized in nursing home B despite several eradication attempts. These outbreaks show the potential for MRSA spread in a nursing home. If the prevalence of MRSA in Norway continues to increase, nursing home staff and residents may have to be included in the groups to be screened for MRSA upon hospital admission.

Authors+Show Affiliations

Department of Microbiology, St Olav University Hospital, Olav Kyrresgt 17, N-7006 Trondheim, Norway. kjersti.wik.larssen@stolav.noNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15951057

Citation

Larssen, K W., et al. "Outbreak of Methicillin-resistant Staphylococcus Aureus in Two Nursing Homes in Central Norway." The Journal of Hospital Infection, vol. 60, no. 4, 2005, pp. 312-6.
Larssen KW, Jacobsen T, Bergh K, et al. Outbreak of methicillin-resistant Staphylococcus aureus in two nursing homes in Central Norway. J Hosp Infect. 2005;60(4):312-6.
Larssen, K. W., Jacobsen, T., Bergh, K., Tvete, P., Kvello, E., & Scheel, O. (2005). Outbreak of methicillin-resistant Staphylococcus aureus in two nursing homes in Central Norway. The Journal of Hospital Infection, 60(4), pp. 312-6.
Larssen KW, et al. Outbreak of Methicillin-resistant Staphylococcus Aureus in Two Nursing Homes in Central Norway. J Hosp Infect. 2005;60(4):312-6. PubMed PMID: 15951057.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outbreak of methicillin-resistant Staphylococcus aureus in two nursing homes in Central Norway. AU - Larssen,K W, AU - Jacobsen,T, AU - Bergh,K, AU - Tvete,P, AU - Kvello,E, AU - Scheel,O, PY - 2004/07/12/received PY - 2004/12/06/accepted PY - 2005/6/14/pubmed PY - 2006/2/8/medline PY - 2005/6/14/entrez SP - 312 EP - 6 JF - The Journal of hospital infection JO - J. Hosp. Infect. VL - 60 IS - 4 N2 - Until recently, infections with methicillin-resistant Staphylococcus aureus (MRSA) have mainly been associated with hospital outbreaks in Norway. However, increasingly cases are contracted outside hospitals. This paper reports the first two outbreaks of MRSA in two nursing homes in central Norway, affecting 23 residents and five staff members. Pulsed-field gel electrophoresis analysis showed that all strains from nursing home A were identical and that the strains from nursing home B were genotypically similar with one or two band differences. Multi-locus sequence typing (MLST) showed that the strains from the two nursing homes belong to clonal complex 45, with each strain being a single-locus variant of sequence type 45 (ST 45), a well-known European epidemic strain. No evident source of the two outbreaks was found, and there was no obvious connection between the two outbreaks. The latter is also supported by the minor differences observed by MLST, suggesting a connection at some time in the past. The outbreaks led to a heavier workload and economic strain on both nursing homes. The outbreak in nursing home A was brought to an end, whereas two residents remained colonized in nursing home B despite several eradication attempts. These outbreaks show the potential for MRSA spread in a nursing home. If the prevalence of MRSA in Norway continues to increase, nursing home staff and residents may have to be included in the groups to be screened for MRSA upon hospital admission. SN - 0195-6701 UR - https://www.unboundmedicine.com/medline/citation/15951057/Outbreak_of_methicillin_resistant_Staphylococcus_aureus_in_two_nursing_homes_in_Central_Norway_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0195-6701(05)00042-3 DB - PRIME DP - Unbound Medicine ER -