Tags

Type your tag names separated by a space and hit enter

Significance of atypical pathogens among community-acquired pneumonia adult patients admitted to hospital in Kuwait.
Med Princ Pract. 2005 Jul-Aug; 14(4):235-40.MP

Abstract

OBJECTIVES

The aim of this study is to determine the microbial etiology and severity of community-acquired pneumonia (CAP) in Kuwait.

SUBJECTS AND METHODS

The severity of consecutive adult CAP cases admitted to 3 hospitals over a 1-year period was classified according to the Pneumonia Outcome Research Team (PORT) severity index. The microbial etiology was determined using standard methods for bacteria and serological tests for atypical and viral pathogens.

RESULTS

The study population was 124 of the 135 admissions; 63 female, 61 male; mean age 41.3+/-18 years. The severity class distribution was: class I 31%, class II 37%, class III 17%, class IV 13%, and class V 2%. Etiological agents were identified from 44 patients (35%), with one pathogen in 31 (25%), two in 9 (7%), and three or more in 4 (3%). The most common pathogens identified were: Mycoplasma pneumoniae in 14 patients (11%), Legionella pneumophila in 10 (8%), Chlamydia pneumoniae in 8 (6%), influenza B virus in 8 (6%), influenza A virus in 5 (4%), Haemophilus influenzae in 4 (3%), Streptococcus pneumoniae in 3 (2%), Staphylococcus aureus in 3 (2%), gram-negative enterobacteria in 5 (4%), Moraxellacatarrhalis in 2 (2%), and viruses in 4 (3%). The yields from laboratory tests were 48% for paired serology, 20% from adequate sputum sample, and 3% from blood culture.

CONCLUSION

Our study shows that a large percentage of mild CAP cases are admitted to hospitals in Kuwait. Atypical pathogens have a significant role in the etiology of CAP. There is overtreatment of CAP with a combination treatment consisting mainly of third-generation chephalosporins and macrolides.

Authors+Show Affiliations

Department of Medicine, Kuwait University, Kuwait. nasser_beh@hsc.edu.kwNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15961932

Citation

Behbehani, N, et al. "Significance of Atypical Pathogens Among Community-acquired Pneumonia Adult Patients Admitted to Hospital in Kuwait." Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre, vol. 14, no. 4, 2005, pp. 235-40.
Behbehani N, Mahmood A, Mokaddas EM, et al. Significance of atypical pathogens among community-acquired pneumonia adult patients admitted to hospital in Kuwait. Med Princ Pract. 2005;14(4):235-40.
Behbehani, N., Mahmood, A., Mokaddas, E. M., Bittar, Z., Jayakrishnan, B., Khadadah, M., Pacsa, A. S., Dhar, R., & Chugh, T. D. (2005). Significance of atypical pathogens among community-acquired pneumonia adult patients admitted to hospital in Kuwait. Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre, 14(4), 235-40.
Behbehani N, et al. Significance of Atypical Pathogens Among Community-acquired Pneumonia Adult Patients Admitted to Hospital in Kuwait. Med Princ Pract. 2005 Jul-Aug;14(4):235-40. PubMed PMID: 15961932.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Significance of atypical pathogens among community-acquired pneumonia adult patients admitted to hospital in Kuwait. AU - Behbehani,N, AU - Mahmood,A, AU - Mokaddas,E M, AU - Bittar,Z, AU - Jayakrishnan,B, AU - Khadadah,M, AU - Pacsa,A S, AU - Dhar,R, AU - Chugh,T D, PY - 2004/04/03/received PY - 2005/6/18/pubmed PY - 2006/2/14/medline PY - 2005/6/18/entrez SP - 235 EP - 40 JF - Medical principles and practice : international journal of the Kuwait University, Health Science Centre JO - Med Princ Pract VL - 14 IS - 4 N2 - OBJECTIVES: The aim of this study is to determine the microbial etiology and severity of community-acquired pneumonia (CAP) in Kuwait. SUBJECTS AND METHODS: The severity of consecutive adult CAP cases admitted to 3 hospitals over a 1-year period was classified according to the Pneumonia Outcome Research Team (PORT) severity index. The microbial etiology was determined using standard methods for bacteria and serological tests for atypical and viral pathogens. RESULTS: The study population was 124 of the 135 admissions; 63 female, 61 male; mean age 41.3+/-18 years. The severity class distribution was: class I 31%, class II 37%, class III 17%, class IV 13%, and class V 2%. Etiological agents were identified from 44 patients (35%), with one pathogen in 31 (25%), two in 9 (7%), and three or more in 4 (3%). The most common pathogens identified were: Mycoplasma pneumoniae in 14 patients (11%), Legionella pneumophila in 10 (8%), Chlamydia pneumoniae in 8 (6%), influenza B virus in 8 (6%), influenza A virus in 5 (4%), Haemophilus influenzae in 4 (3%), Streptococcus pneumoniae in 3 (2%), Staphylococcus aureus in 3 (2%), gram-negative enterobacteria in 5 (4%), Moraxellacatarrhalis in 2 (2%), and viruses in 4 (3%). The yields from laboratory tests were 48% for paired serology, 20% from adequate sputum sample, and 3% from blood culture. CONCLUSION: Our study shows that a large percentage of mild CAP cases are admitted to hospitals in Kuwait. Atypical pathogens have a significant role in the etiology of CAP. There is overtreatment of CAP with a combination treatment consisting mainly of third-generation chephalosporins and macrolides. SN - 1011-7571 UR - https://www.unboundmedicine.com/medline/citation/15961932/Significance_of_atypical_pathogens_among_community_acquired_pneumonia_adult_patients_admitted_to_hospital_in_Kuwait_ L2 - https://www.karger.com?DOI=10.1159/000085741 DB - PRIME DP - Unbound Medicine ER -