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Angioedema acute hypersensitivity reaction to injectable hyaluronic acid.
Dermatol Surg 2005; 31(5):577-9DS

Abstract

BACKGROUND

Injectable hyaluronic acid was introduced to European markets in 1996 and has demonstrated a high safety profile. We describe the first reported case of angioedema-type hypersensitivity following injection of the upper lip with non-animal-stabilized hyaluronic acid (NASHA) gel.

OBJECTIVE

To report a case and discuss a potential mechanism for and treatment of angioedema-type hypersensitivity following injection with NASHA gel into the upper lip.

METHODS AND MATERIALS

Not applicable.

RESULTS

Not applicable.

CONCLUSION

Although injectable hyaluronic acid has a high safety profile, this reaction is dramatic. Treatments and potential mechanisms are discussed.

Authors+Show Affiliations

Center for Dermatologic Surgery, Cooper University Hospital, Marlton, New Jersey 08053, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

15962746

Citation

Leonhardt, Janie M., et al. "Angioedema Acute Hypersensitivity Reaction to Injectable Hyaluronic Acid." Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.], vol. 31, no. 5, 2005, pp. 577-9.
Leonhardt JM, Lawrence N, Narins RS. Angioedema acute hypersensitivity reaction to injectable hyaluronic acid. Dermatol Surg. 2005;31(5):577-9.
Leonhardt, J. M., Lawrence, N., & Narins, R. S. (2005). Angioedema acute hypersensitivity reaction to injectable hyaluronic acid. Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.], 31(5), pp. 577-9.
Leonhardt JM, Lawrence N, Narins RS. Angioedema Acute Hypersensitivity Reaction to Injectable Hyaluronic Acid. Dermatol Surg. 2005;31(5):577-9. PubMed PMID: 15962746.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Angioedema acute hypersensitivity reaction to injectable hyaluronic acid. AU - Leonhardt,Janie M, AU - Lawrence,Naomi, AU - Narins,Rhoda S, PY - 2005/6/21/pubmed PY - 2005/7/1/medline PY - 2005/6/21/entrez SP - 577 EP - 9 JF - Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] JO - Dermatol Surg VL - 31 IS - 5 N2 - BACKGROUND: Injectable hyaluronic acid was introduced to European markets in 1996 and has demonstrated a high safety profile. We describe the first reported case of angioedema-type hypersensitivity following injection of the upper lip with non-animal-stabilized hyaluronic acid (NASHA) gel. OBJECTIVE: To report a case and discuss a potential mechanism for and treatment of angioedema-type hypersensitivity following injection with NASHA gel into the upper lip. METHODS AND MATERIALS: Not applicable. RESULTS: Not applicable. CONCLUSION: Although injectable hyaluronic acid has a high safety profile, this reaction is dramatic. Treatments and potential mechanisms are discussed. SN - 1076-0512 UR - https://www.unboundmedicine.com/medline/citation/15962746/Angioedema_acute_hypersensitivity_reaction_to_injectable_hyaluronic_acid_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1076-0512&date=2005&volume=31&issue=5&spage=577 DB - PRIME DP - Unbound Medicine ER -