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[Spontaneous rupture of the liver in HELLP syndrome].
Geburtshilfe Frauenheilkd. 1992 Mar; 52(3):152-6.GF

Abstract

Spontaneous hepatic rupture in pregnancy is a rare, but dangerous complication of acute or progressing pre-eclampsia. Pain in the right upper quadrant is the most important clinical symptom and should prompt immediate laboratory evaluation (transaminase, coagulation profile, platelet count, red and white blood count). If the diagnosis of HELLP syndrome is confirmed, close supervision in an intensive care unit is mandatory. The danger of pre- or postpartal open hepatic rupture must be considered. Pain in the right upper abdomen and signs of abdominal mass bleeding occurring within a HELLP syndrome are important evidence for hepatic rupture. Immediate ultrasonic examination may verify the tentative diagnosis. The usual therapy is then laparotomy with attempted surgical haemorrhage control. A conservative clinical haemorrhage control attempt is possible in exceptional cases only. Patients developing a HELLP syndrome although otherwise in seemingly perfect health, require closely meshed monitoring to exclude hepatic rupture.

Authors+Show Affiliations

Universitäts-Frauenklinik Ulm.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

ger

PubMed ID

1597274

Citation

Volz, J, et al. "[Spontaneous Rupture of the Liver in HELLP Syndrome]." Geburtshilfe Und Frauenheilkunde, vol. 52, no. 3, 1992, pp. 152-6.
Volz J, Volz E, Stoz F, et al. [Spontaneous rupture of the liver in HELLP syndrome]. Geburtshilfe Frauenheilkd. 1992;52(3):152-6.
Volz, J., Volz, E., Stoz, F., & Keckstein, J. (1992). [Spontaneous rupture of the liver in HELLP syndrome]. Geburtshilfe Und Frauenheilkunde, 52(3), 152-6.
Volz J, et al. [Spontaneous Rupture of the Liver in HELLP Syndrome]. Geburtshilfe Frauenheilkd. 1992;52(3):152-6. PubMed PMID: 1597274.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Spontaneous rupture of the liver in HELLP syndrome]. AU - Volz,J, AU - Volz,E, AU - Stoz,F, AU - Keckstein,J, PY - 1992/3/1/pubmed PY - 1992/3/1/medline PY - 1992/3/1/entrez SP - 152 EP - 6 JF - Geburtshilfe und Frauenheilkunde JO - Geburtshilfe Frauenheilkd VL - 52 IS - 3 N2 - Spontaneous hepatic rupture in pregnancy is a rare, but dangerous complication of acute or progressing pre-eclampsia. Pain in the right upper quadrant is the most important clinical symptom and should prompt immediate laboratory evaluation (transaminase, coagulation profile, platelet count, red and white blood count). If the diagnosis of HELLP syndrome is confirmed, close supervision in an intensive care unit is mandatory. The danger of pre- or postpartal open hepatic rupture must be considered. Pain in the right upper abdomen and signs of abdominal mass bleeding occurring within a HELLP syndrome are important evidence for hepatic rupture. Immediate ultrasonic examination may verify the tentative diagnosis. The usual therapy is then laparotomy with attempted surgical haemorrhage control. A conservative clinical haemorrhage control attempt is possible in exceptional cases only. Patients developing a HELLP syndrome although otherwise in seemingly perfect health, require closely meshed monitoring to exclude hepatic rupture. SN - 0016-5751 UR - https://www.unboundmedicine.com/medline/citation/1597274/[Spontaneous_rupture_of_the_liver_in_HELLP_syndrome]_ DB - PRIME DP - Unbound Medicine ER -