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Obesity in Spanish schoolchildren: relationship with lipid profile and insulin resistance.
Obes Res. 2005 Jun; 13(6):959-63.OR

Abstract

This article reports cross-sectional data from a total of 1048 children, 6 to 8 years of age, categorized by presence or absence of obesity, who participated in a voluntary survey of cardiovascular risk factors in Spain over the period of 1998 to 2000, to establish the relationship between obesity and its metabolic consequences at this age. The prevalence of obesity and overweight were 9.4% and 15.7%, respectively, in boys and 10.5% and 18.0%, respectively, in girls. We observed that, in both sexes, obese children had higher triglycerides and lower high-density lipoprotein-cholesterol levels than non-obese children. No differences were found in plasma glucose or low-density lipoprotein-cholesterol levels between normal and obese children. However, we observed that insulin levels and the homeostasis model assessment for insulin resistance were significantly (p<0.001) higher in obese children of both sexes but that free fatty acid levels were lower in obese children than in nonobese children, with a statistical significance in girls (0.72+/-0.30 vs. 0.61+/-0.16 mEq/liter). In summary, our survey found some metabolic consequences of obesity similar to those found in adults (elevated triglycerides, insulin, and the homeostasis model assessment for insulin resistance, and lower high-density lipoprotein-cholesterol). However, other features (glucose, total cholesterol, low-density lipoprotein-cholesterol, and free fatty acid levels) were found to behave differently, indicating that the association of obesity with risk factors seems to change as the children age and may depend on the chronology of sexual maturation.

Authors+Show Affiliations

Unidad de Lípidos, Fundación Jiménez Díaz, Avda. Reyes Católicos, 2, 28040 Madrid, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15976136

Citation

Garcés, Carmen, et al. "Obesity in Spanish Schoolchildren: Relationship With Lipid Profile and Insulin Resistance." Obesity Research, vol. 13, no. 6, 2005, pp. 959-63.
Garcés C, Gutierrez-Guisado J, Benavente M, et al. Obesity in Spanish schoolchildren: relationship with lipid profile and insulin resistance. Obes Res. 2005;13(6):959-63.
Garcés, C., Gutierrez-Guisado, J., Benavente, M., Cano, B., Viturro, E., Ortega, H., & de Oya, M. (2005). Obesity in Spanish schoolchildren: relationship with lipid profile and insulin resistance. Obesity Research, 13(6), 959-63.
Garcés C, et al. Obesity in Spanish Schoolchildren: Relationship With Lipid Profile and Insulin Resistance. Obes Res. 2005;13(6):959-63. PubMed PMID: 15976136.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Obesity in Spanish schoolchildren: relationship with lipid profile and insulin resistance. AU - Garcés,Carmen, AU - Gutierrez-Guisado,Javier, AU - Benavente,Mercedes, AU - Cano,Beatriz, AU - Viturro,Enrique, AU - Ortega,Henar, AU - de Oya,Manuel, PY - 2005/6/25/pubmed PY - 2005/10/21/medline PY - 2005/6/25/entrez SP - 959 EP - 63 JF - Obesity research JO - Obes. Res. VL - 13 IS - 6 N2 - This article reports cross-sectional data from a total of 1048 children, 6 to 8 years of age, categorized by presence or absence of obesity, who participated in a voluntary survey of cardiovascular risk factors in Spain over the period of 1998 to 2000, to establish the relationship between obesity and its metabolic consequences at this age. The prevalence of obesity and overweight were 9.4% and 15.7%, respectively, in boys and 10.5% and 18.0%, respectively, in girls. We observed that, in both sexes, obese children had higher triglycerides and lower high-density lipoprotein-cholesterol levels than non-obese children. No differences were found in plasma glucose or low-density lipoprotein-cholesterol levels between normal and obese children. However, we observed that insulin levels and the homeostasis model assessment for insulin resistance were significantly (p<0.001) higher in obese children of both sexes but that free fatty acid levels were lower in obese children than in nonobese children, with a statistical significance in girls (0.72+/-0.30 vs. 0.61+/-0.16 mEq/liter). In summary, our survey found some metabolic consequences of obesity similar to those found in adults (elevated triglycerides, insulin, and the homeostasis model assessment for insulin resistance, and lower high-density lipoprotein-cholesterol). However, other features (glucose, total cholesterol, low-density lipoprotein-cholesterol, and free fatty acid levels) were found to behave differently, indicating that the association of obesity with risk factors seems to change as the children age and may depend on the chronology of sexual maturation. SN - 1071-7323 UR - https://www.unboundmedicine.com/medline/citation/15976136/Obesity_in_Spanish_schoolchildren:_relationship_with_lipid_profile_and_insulin_resistance_ L2 - https://doi.org/10.1038/oby.2005.111 DB - PRIME DP - Unbound Medicine ER -