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Effects of early intake of fruit or vegetables in relation to later asthma and allergic sensitization in school-age children.
Acta Paediatr 2005; 94(2):147-54AP

Abstract

AIM

To assess the associations between nutrition supplements in infancy and later asthma and allergy in school-age children, and to explore the impact of environmental factors in early life.

METHODS

Five hundred and two children underwent clinical examination, skin prick test and a second parentally completed questionnaire within 2 y of a cross-sectional questionnairebased study, including 4585 primary school children (6-16 y old) in 1994 from urban Oslo (37%), the mountainous area of Hallingdal (42%), and the industrial, coastal area of Odda (21%). The children were selected from the 1994 survey on the basis of reported diagnosed asthma (n=166), wheeze in the last 12 mo (n=155) and no asthma/no wheeze (n=181). Questions were related to nutrition and environmental exposure in early life. Possible associations between allergic sensitization or asthma at school age and exposures were estimated by logistic regression analysis, adjusting for potential confounders.

RESULTS

Daily intake of fresh fruit or vegetables, but not extra vitamins or cod liver oil supplements, in infancy decreased the risk of asthma (adjusted odds ratio (aOR) 0.57 (95% confidence interval (CI): 0.37-0.88). Early supplements of cod liver oil and extra vitamins were associated with increased allergic sensitization (aOR 1.78 (95% CI: 1.03-3.07) and 1.71 (95% CI: 1.01-2.88), respectively). A significantly higher prevalence of allergic sensitization was found in children living in Hallingdal compared to Odda, while the latter children, on the other hand, had the highest prevalence of house dust mite allergy (p = 0.001 vs Hallingdal and p = 0.04 vs Oslo).

CONCLUSION

The present study suggests that the early introduction of daily fresh fruit or vegetables may decrease the risk of asthma after 1 y of life, whereas allergic sensitization at school age seemed to increase with extra vitamin and cod liver oil supplements during infancy. Living area influenced allergic sensitization, with differences between coastal and inland areas.

Authors+Show Affiliations

Geilomo Children's Hospital for Asthma and Allergy, Geilo and Sandvika, Norway. fnja@online.noNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15981746

Citation

Njå, Frode, et al. "Effects of Early Intake of Fruit or Vegetables in Relation to Later Asthma and Allergic Sensitization in School-age Children." Acta Paediatrica (Oslo, Norway : 1992), vol. 94, no. 2, 2005, pp. 147-54.
Njå F, Nystad W, Lødrup Carlsen KC, et al. Effects of early intake of fruit or vegetables in relation to later asthma and allergic sensitization in school-age children. Acta Paediatr. 2005;94(2):147-54.
Njå, F., Nystad, W., Lødrup Carlsen, K. C., Hetlevik, O., & Carlsen, K. H. (2005). Effects of early intake of fruit or vegetables in relation to later asthma and allergic sensitization in school-age children. Acta Paediatrica (Oslo, Norway : 1992), 94(2), pp. 147-54.
Njå F, et al. Effects of Early Intake of Fruit or Vegetables in Relation to Later Asthma and Allergic Sensitization in School-age Children. Acta Paediatr. 2005;94(2):147-54. PubMed PMID: 15981746.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of early intake of fruit or vegetables in relation to later asthma and allergic sensitization in school-age children. AU - Njå,Frode, AU - Nystad,Wenche, AU - Lødrup Carlsen,Karin C, AU - Hetlevik,Oystein, AU - Carlsen,Kai-Håkon, PY - 2005/6/29/pubmed PY - 2005/7/16/medline PY - 2005/6/29/entrez SP - 147 EP - 54 JF - Acta paediatrica (Oslo, Norway : 1992) JO - Acta Paediatr. VL - 94 IS - 2 N2 - AIM: To assess the associations between nutrition supplements in infancy and later asthma and allergy in school-age children, and to explore the impact of environmental factors in early life. METHODS: Five hundred and two children underwent clinical examination, skin prick test and a second parentally completed questionnaire within 2 y of a cross-sectional questionnairebased study, including 4585 primary school children (6-16 y old) in 1994 from urban Oslo (37%), the mountainous area of Hallingdal (42%), and the industrial, coastal area of Odda (21%). The children were selected from the 1994 survey on the basis of reported diagnosed asthma (n=166), wheeze in the last 12 mo (n=155) and no asthma/no wheeze (n=181). Questions were related to nutrition and environmental exposure in early life. Possible associations between allergic sensitization or asthma at school age and exposures were estimated by logistic regression analysis, adjusting for potential confounders. RESULTS: Daily intake of fresh fruit or vegetables, but not extra vitamins or cod liver oil supplements, in infancy decreased the risk of asthma (adjusted odds ratio (aOR) 0.57 (95% confidence interval (CI): 0.37-0.88). Early supplements of cod liver oil and extra vitamins were associated with increased allergic sensitization (aOR 1.78 (95% CI: 1.03-3.07) and 1.71 (95% CI: 1.01-2.88), respectively). A significantly higher prevalence of allergic sensitization was found in children living in Hallingdal compared to Odda, while the latter children, on the other hand, had the highest prevalence of house dust mite allergy (p = 0.001 vs Hallingdal and p = 0.04 vs Oslo). CONCLUSION: The present study suggests that the early introduction of daily fresh fruit or vegetables may decrease the risk of asthma after 1 y of life, whereas allergic sensitization at school age seemed to increase with extra vitamin and cod liver oil supplements during infancy. Living area influenced allergic sensitization, with differences between coastal and inland areas. SN - 0803-5253 UR - https://www.unboundmedicine.com/medline/citation/15981746/Effects_of_early_intake_of_fruit_or_vegetables_in_relation_to_later_asthma_and_allergic_sensitization_in_school_age_children_ L2 - https://doi.org/10.1111/j.1651-2227.2005.tb01882.x DB - PRIME DP - Unbound Medicine ER -