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Characterization of macular edema from various etiologies by optical coherence tomography.
Am J Ophthalmol. 2005 Aug; 140(2):200-6.AJ

Abstract

PURPOSE

To use optical coherence tomography (OCT) to characterize the intraretinal changes associated with macular edema (ME) according to its etiology.

DESIGN

Observational case series.

METHODS

Seventy-eight eyes of 78 patients with ME were examined retrospectively by OCT, using the Humphrey 2000 OCT system (Humphrey Co., San Leandro, California). ME etiologies were diabetic retinopathy (27 cases), central retinal vein occlusion (18 cases), pseudophakia (15 cases), posterior uveitis (10 cases), and retinitis pigmentosa (eight cases). Macular thickness was measured using OCT mapping software. It was correlated with logarithmic visual acuity.

RESULTS

In 72 of 78 cases (92%), ME was located in the outer retinal layers. Serous retinal detachment was present in 29 of 78 cases (37%). It was most frequent in central retinal vein occlusion (10 of 18 cases, 56%). There were no significant differences in visual acuity (P = .26) or macular thickness (P = .95) whether or not serous retinal detachment was combined with ME. The posterior hyaloid was partially detached in 17 of 78 cases (22%) of overall cases. Serous retinal detachment did not correlate with partial posterior hyaloid detachment (P = .6). Mean macular thickness ranged from 506 microm in central retinal vein occlusion to 373 microm in retinitis pigmentosa. Visual acuity correlated with macular thickness in diabetic retinopathy (R = 0.55; P = .0027) and pseudophakia cases (R = 0.66; P = .016).

CONCLUSIONS

OCT characterized the retinal morphologic changes associated with ME, especially the vitreomacular relationship and sub-clinical serous macular detachment. This detachment did not correlate with poor visual acuity. Macular thickening only correlated with visual loss in diabetic retinopathy and pseudophakia.

Authors+Show Affiliations

Department of Ophthalmology, Hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, Université Paris 7, Paris, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15992752

Citation

Catier, Antoine, et al. "Characterization of Macular Edema From Various Etiologies By Optical Coherence Tomography." American Journal of Ophthalmology, vol. 140, no. 2, 2005, pp. 200-6.
Catier A, Tadayoni R, Paques M, et al. Characterization of macular edema from various etiologies by optical coherence tomography. Am J Ophthalmol. 2005;140(2):200-6.
Catier, A., Tadayoni, R., Paques, M., Erginay, A., Haouchine, B., Gaudric, A., & Massin, P. (2005). Characterization of macular edema from various etiologies by optical coherence tomography. American Journal of Ophthalmology, 140(2), 200-6.
Catier A, et al. Characterization of Macular Edema From Various Etiologies By Optical Coherence Tomography. Am J Ophthalmol. 2005;140(2):200-6. PubMed PMID: 15992752.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Characterization of macular edema from various etiologies by optical coherence tomography. AU - Catier,Antoine, AU - Tadayoni,Ramin, AU - Paques,Michel, AU - Erginay,Ali, AU - Haouchine,Belkacem, AU - Gaudric,Alain, AU - Massin,Pascale, PY - 2004/10/08/received PY - 2005/02/25/revised PY - 2005/02/25/accepted PY - 2005/7/5/pubmed PY - 2005/9/1/medline PY - 2005/7/5/entrez SP - 200 EP - 6 JF - American journal of ophthalmology JO - Am J Ophthalmol VL - 140 IS - 2 N2 - PURPOSE: To use optical coherence tomography (OCT) to characterize the intraretinal changes associated with macular edema (ME) according to its etiology. DESIGN: Observational case series. METHODS: Seventy-eight eyes of 78 patients with ME were examined retrospectively by OCT, using the Humphrey 2000 OCT system (Humphrey Co., San Leandro, California). ME etiologies were diabetic retinopathy (27 cases), central retinal vein occlusion (18 cases), pseudophakia (15 cases), posterior uveitis (10 cases), and retinitis pigmentosa (eight cases). Macular thickness was measured using OCT mapping software. It was correlated with logarithmic visual acuity. RESULTS: In 72 of 78 cases (92%), ME was located in the outer retinal layers. Serous retinal detachment was present in 29 of 78 cases (37%). It was most frequent in central retinal vein occlusion (10 of 18 cases, 56%). There were no significant differences in visual acuity (P = .26) or macular thickness (P = .95) whether or not serous retinal detachment was combined with ME. The posterior hyaloid was partially detached in 17 of 78 cases (22%) of overall cases. Serous retinal detachment did not correlate with partial posterior hyaloid detachment (P = .6). Mean macular thickness ranged from 506 microm in central retinal vein occlusion to 373 microm in retinitis pigmentosa. Visual acuity correlated with macular thickness in diabetic retinopathy (R = 0.55; P = .0027) and pseudophakia cases (R = 0.66; P = .016). CONCLUSIONS: OCT characterized the retinal morphologic changes associated with ME, especially the vitreomacular relationship and sub-clinical serous macular detachment. This detachment did not correlate with poor visual acuity. Macular thickening only correlated with visual loss in diabetic retinopathy and pseudophakia. SN - 0002-9394 UR - https://www.unboundmedicine.com/medline/citation/15992752/Characterization_of_macular_edema_from_various_etiologies_by_optical_coherence_tomography_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9394(05)00277-1 DB - PRIME DP - Unbound Medicine ER -