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Tempos of gene locus deletions and duplications and their relationship to recombination rate during diploid and polyploid evolution in the Aegilops-Triticum alliance.
Genetics. 2005 Sep; 171(1):323-32.G

Abstract

The origin of tetraploid wheat and the divergence of diploid ancestors of wheat A and D genomes were estimated to have occurred 0.36 and 2.7 million years ago, respectively. These estimates and the evolutionary history of 3159 gene loci were used to estimate the rates with which gene loci have been deleted and duplicated during the evolution of wheat diploid ancestors and during the evolution of polyploid wheat. During diploid evolution, the deletion rate was 2.1 x 10(-3) locus(-1) MY(-1) for single-copy loci and 1.0 x 10(-2) locus(-1) MY(-1) for loci in paralogous sets. Loci were duplicated with a rate of 2.9 x 10(-3) locus(-1) MY(-1) during diploid evolution. During polyploid evolution, locus deletion and locus duplication rates were 1.8 x 10(-2) and 1.8 x 10(-3) locus(-1) MY(-1), respectively. Locus deletion and duplication rates correlated positively with the distance of the locus from the centromere and the recombination rate during diploid evolution. The functions of deleted and duplicated loci were inferred to gain insight into the surprisingly high rate of deletions of loci present apparently only once in a genome. The significance of these findings for genome evolution at the diploid and polyploid level is discussed.

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Authors+Show Affiliations

Dvorak J
Department of Plant Sciences, University of California, Davis, California 95616, USA. jdvorak@ucdavis.edu
Akhunov ED
No affiliation info available

MeSH

CentromereChromosome MappingChromosomes, PlantDiploidyEvolution, MolecularGene DeletionGene DuplicationGenetic VariationGenome, PlantLinear ModelsMolecular Sequence DataPhylogenyPlant ProteinsPoaceaePolyploidyRecombination, GeneticTime FactorsTriticum

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

15996988

Citation

Dvorak, Jan, and Eduard D. Akhunov. "Tempos of Gene Locus Deletions and Duplications and Their Relationship to Recombination Rate During Diploid and Polyploid Evolution in the Aegilops-Triticum Alliance." Genetics, vol. 171, no. 1, 2005, pp. 323-32.
Dvorak J, Akhunov ED. Tempos of gene locus deletions and duplications and their relationship to recombination rate during diploid and polyploid evolution in the Aegilops-Triticum alliance. Genetics. 2005;171(1):323-32.
Dvorak, J., & Akhunov, E. D. (2005). Tempos of gene locus deletions and duplications and their relationship to recombination rate during diploid and polyploid evolution in the Aegilops-Triticum alliance. Genetics, 171(1), 323-32.
Dvorak J, Akhunov ED. Tempos of Gene Locus Deletions and Duplications and Their Relationship to Recombination Rate During Diploid and Polyploid Evolution in the Aegilops-Triticum Alliance. Genetics. 2005;171(1):323-32. PubMed PMID: 15996988.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Tempos of gene locus deletions and duplications and their relationship to recombination rate during diploid and polyploid evolution in the Aegilops-Triticum alliance. AU - Dvorak,Jan, AU - Akhunov,Eduard D, Y1 - 2005/07/04/ PY - 2005/7/6/pubmed PY - 2006/5/27/medline PY - 2005/7/6/entrez SP - 323 EP - 32 JF - Genetics JO - Genetics VL - 171 IS - 1 N2 - The origin of tetraploid wheat and the divergence of diploid ancestors of wheat A and D genomes were estimated to have occurred 0.36 and 2.7 million years ago, respectively. These estimates and the evolutionary history of 3159 gene loci were used to estimate the rates with which gene loci have been deleted and duplicated during the evolution of wheat diploid ancestors and during the evolution of polyploid wheat. During diploid evolution, the deletion rate was 2.1 x 10(-3) locus(-1) MY(-1) for single-copy loci and 1.0 x 10(-2) locus(-1) MY(-1) for loci in paralogous sets. Loci were duplicated with a rate of 2.9 x 10(-3) locus(-1) MY(-1) during diploid evolution. During polyploid evolution, locus deletion and locus duplication rates were 1.8 x 10(-2) and 1.8 x 10(-3) locus(-1) MY(-1), respectively. Locus deletion and duplication rates correlated positively with the distance of the locus from the centromere and the recombination rate during diploid evolution. The functions of deleted and duplicated loci were inferred to gain insight into the surprisingly high rate of deletions of loci present apparently only once in a genome. The significance of these findings for genome evolution at the diploid and polyploid level is discussed. SN - 0016-6731 UR - https://www.unboundmedicine.com/medline/citation/15996988/Tempos_of_gene_locus_deletions_and_duplications_and_their_relationship_to_recombination_rate_during_diploid_and_polyploid_evolution_in_the_Aegilops_Triticum_alliance_ DB - PRIME DP - Unbound Medicine ER -