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[Primitive neuroectodermal tumor arising 8 years after chemotherapy and radiotherapy for acute lymphoblastic leukemia: case report].
No Shinkei Geka. 2005 Jul; 33(7):717-22.NS

Abstract

We report a case of primitive neuroectodermal tumor (PNET) arising 8 years after chemotherapy and radiotherapy for acute lymphoblastic leukemia. A 15-year-old boy with a history of acute lymphoblastic leukemia, at the age of 7, underwent chemotherapy and 14Gy of radiotherapy to the whole brain. He was admitted to our department due to the development of aphasia, right hemiparesis and generalized convulsive seizure. MRI showed an irregularly enhanced mass in the left frontal lobe. A gross total removal of the tumor was performed and histological examination showed it to be PNET. Postoperatively, the patient underwent 20Gy of radiotherapy to the whole brain and 42Gy of local radiotherapy. Follow-up MRI showed no evidence of recurrent tumor 4 months after the radiotherapy. This tumor was thought to be a secondary brain tumor arising in this survivor of childhood acute lymphoblastic leukemia and it is a rare complication of successful leukemia treatment.

Authors+Show Affiliations

Department of Neurosurgery, Fukui Prefectural Hospital, 2-8-1 Yotsui, Fukui-shi, Fukui 910 - 0846, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

jpn

PubMed ID

16001813

Citation

Yoshida, Yuya, et al. "[Primitive Neuroectodermal Tumor Arising 8 Years After Chemotherapy and Radiotherapy for Acute Lymphoblastic Leukemia: Case Report]." No Shinkei Geka. Neurological Surgery, vol. 33, no. 7, 2005, pp. 717-22.
Yoshida Y, Toma Y, Arai M, et al. [Primitive neuroectodermal tumor arising 8 years after chemotherapy and radiotherapy for acute lymphoblastic leukemia: case report]. No Shinkei Geka. 2005;33(7):717-22.
Yoshida, Y., Toma, Y., Arai, M., Higashi, R., Kashihara, K., & Kaizaki, Y. (2005). [Primitive neuroectodermal tumor arising 8 years after chemotherapy and radiotherapy for acute lymphoblastic leukemia: case report]. No Shinkei Geka. Neurological Surgery, 33(7), 717-22.
Yoshida Y, et al. [Primitive Neuroectodermal Tumor Arising 8 Years After Chemotherapy and Radiotherapy for Acute Lymphoblastic Leukemia: Case Report]. No Shinkei Geka. 2005;33(7):717-22. PubMed PMID: 16001813.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Primitive neuroectodermal tumor arising 8 years after chemotherapy and radiotherapy for acute lymphoblastic leukemia: case report]. AU - Yoshida,Yuya, AU - Toma,Yasuo, AU - Arai,Masayuki, AU - Higashi,Ryo, AU - Kashihara,Kengo, AU - Kaizaki,Yasuharu, PY - 2005/7/9/pubmed PY - 2005/8/6/medline PY - 2005/7/9/entrez SP - 717 EP - 22 JF - No shinkei geka. Neurological surgery JO - No Shinkei Geka VL - 33 IS - 7 N2 - We report a case of primitive neuroectodermal tumor (PNET) arising 8 years after chemotherapy and radiotherapy for acute lymphoblastic leukemia. A 15-year-old boy with a history of acute lymphoblastic leukemia, at the age of 7, underwent chemotherapy and 14Gy of radiotherapy to the whole brain. He was admitted to our department due to the development of aphasia, right hemiparesis and generalized convulsive seizure. MRI showed an irregularly enhanced mass in the left frontal lobe. A gross total removal of the tumor was performed and histological examination showed it to be PNET. Postoperatively, the patient underwent 20Gy of radiotherapy to the whole brain and 42Gy of local radiotherapy. Follow-up MRI showed no evidence of recurrent tumor 4 months after the radiotherapy. This tumor was thought to be a secondary brain tumor arising in this survivor of childhood acute lymphoblastic leukemia and it is a rare complication of successful leukemia treatment. SN - 0301-2603 UR - https://www.unboundmedicine.com/medline/citation/16001813/[Primitive_neuroectodermal_tumor_arising_8_years_after_chemotherapy_and_radiotherapy_for_acute_lymphoblastic_leukemia:_case_report]_ L2 - https://webview.isho.jp/openurl?rft.genre=article&rft.issn=0301-2603&rft.volume=33&rft.issue=7&rft.spage=717 DB - PRIME DP - Unbound Medicine ER -