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Chronic venous insufficiency in Italy: the 24-cities cohort study.
Eur J Vasc Endovasc Surg 2005; 30(4):422-9EJ

Abstract

OBJECTIVE

To assess the relationship between sex, age, geographical region, lower limb symptoms and the presence of trunk varicose veins and venous incompetence.

DESIGN

Cross-sectional population study in 24 cities in the North, centre and South of Italy.

PARTICIPANTS

Five thousand two hundred and forty-seven people were selected during spring and summer 2003 by advertising on television, in newspapers, and by leaflets in 24 Italian cities. In all 5187 (4457 [85.9%] women and 730 men [14.1%]) volunteers were assessed. The median age was 54 (range: 18-90) years for the women and 61 (range: 18-89) years for the men.

METHODS

Self-administered questionnaire on subjective symptoms of chronic venous insufficiency (CVI) in the lower limbs, and clinical examination, including colour duplex ultrasonography to assess the presence and severity of varicose veins.

RESULTS

Overall only 22.7% of the subjects examined were free of visible signs of venous disease, with approximately 53% of the population over 50 years of age showing some venous reflux. People living in Southern Italy were more severely affected than those living in the North. Varicosities and telangiectases were the most frequent objective signs in both sexes. Trunk varicosities (27%) and saphenous reflux (41%) increased with age and were more common in men; in contrast, minor objective symptoms such as telangiectases (70%), as well as subjective symptoms such as heavy (79%) and tired legs (78%), were more common in women and were not age-related.

CONCLUSIONS

Venous disease is very common in Italy, in particular in people living in the South. A correlation between varicose veins and venous incompetence is more marked in men, while minor objective and subjective symptoms prevail in women. The findings from this non-random sample closely match results from previous studies, in which random sampling was used.

Authors+Show Affiliations

Scientific Institute H. San Raffaele, Vita-Salute University, Milan, Italy.

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16009576

Citation

Chiesa, R, et al. "Chronic Venous Insufficiency in Italy: the 24-cities Cohort Study." European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery, vol. 30, no. 4, 2005, pp. 422-9.
Chiesa R, Marone EM, Limoni C, et al. Chronic venous insufficiency in Italy: the 24-cities cohort study. Eur J Vasc Endovasc Surg. 2005;30(4):422-9.
Chiesa, R., Marone, E. M., Limoni, C., Volonté, M., Schaefer, E., & Petrini, O. (2005). Chronic venous insufficiency in Italy: the 24-cities cohort study. European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery, 30(4), pp. 422-9.
Chiesa R, et al. Chronic Venous Insufficiency in Italy: the 24-cities Cohort Study. Eur J Vasc Endovasc Surg. 2005;30(4):422-9. PubMed PMID: 16009576.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chronic venous insufficiency in Italy: the 24-cities cohort study. AU - Chiesa,R, AU - Marone,E M, AU - Limoni,C, AU - Volonté,M, AU - Schaefer,E, AU - Petrini,O, PY - 2004/07/08/received PY - 2005/06/02/accepted PY - 2005/7/13/pubmed PY - 2005/10/26/medline PY - 2005/7/13/entrez SP - 422 EP - 9 JF - European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery JO - Eur J Vasc Endovasc Surg VL - 30 IS - 4 N2 - OBJECTIVE: To assess the relationship between sex, age, geographical region, lower limb symptoms and the presence of trunk varicose veins and venous incompetence. DESIGN: Cross-sectional population study in 24 cities in the North, centre and South of Italy. PARTICIPANTS: Five thousand two hundred and forty-seven people were selected during spring and summer 2003 by advertising on television, in newspapers, and by leaflets in 24 Italian cities. In all 5187 (4457 [85.9%] women and 730 men [14.1%]) volunteers were assessed. The median age was 54 (range: 18-90) years for the women and 61 (range: 18-89) years for the men. METHODS: Self-administered questionnaire on subjective symptoms of chronic venous insufficiency (CVI) in the lower limbs, and clinical examination, including colour duplex ultrasonography to assess the presence and severity of varicose veins. RESULTS: Overall only 22.7% of the subjects examined were free of visible signs of venous disease, with approximately 53% of the population over 50 years of age showing some venous reflux. People living in Southern Italy were more severely affected than those living in the North. Varicosities and telangiectases were the most frequent objective signs in both sexes. Trunk varicosities (27%) and saphenous reflux (41%) increased with age and were more common in men; in contrast, minor objective symptoms such as telangiectases (70%), as well as subjective symptoms such as heavy (79%) and tired legs (78%), were more common in women and were not age-related. CONCLUSIONS: Venous disease is very common in Italy, in particular in people living in the South. A correlation between varicose veins and venous incompetence is more marked in men, while minor objective and subjective symptoms prevail in women. The findings from this non-random sample closely match results from previous studies, in which random sampling was used. SN - 1078-5884 UR - https://www.unboundmedicine.com/medline/citation/16009576/Chronic_venous_insufficiency_in_Italy:_the_24_cities_cohort_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1078-5884(05)00331-X DB - PRIME DP - Unbound Medicine ER -