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[Chemistry of polysaccharide Lzps-1 from Ganoderma lucidum spore and anti-tumor activity of its total polysaccharides].
Yao Xue Xue Bao. 2005 Apr; 40(4):347-50.YX

Abstract

AIM

To study the structure and anti-tumor activity of polysaccharide from Ganoderma lucidum spore treated with microwave.

METHODS

DEAE-cellulose and Sephadex G-50 column chromatography were used to isolate and purify the polysaccharide whose structure was characterized by using chemical and spectral methods.

RESULTS AND CONCLUSION

One polysaccharide, named Lzps-1 was obtained from the water extract, with its molecular weight estimated by HPGPC to be 8000. Its structure was investigated to be glucan. The total polysaccharides, Lzps processed antitumor activity against sarcoma 180 and Lewis lung cancer in mice and enhanced the NK cell activity. Lzps-1 is obtained for the first time from Ganoderma spore Lzps has anti-tumor activity.

Authors+Show Affiliations

Shanghai Institute of Organic Chemistry, Shanghai 200032, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

chi

PubMed ID

16011264

Citation

Jiang, Yan, et al. "[Chemistry of Polysaccharide Lzps-1 From Ganoderma Lucidum Spore and Anti-tumor Activity of Its Total Polysaccharides]." Yao Xue Xue Bao = Acta Pharmaceutica Sinica, vol. 40, no. 4, 2005, pp. 347-50.
Jiang Y, Wang H, Lü L, et al. [Chemistry of polysaccharide Lzps-1 from Ganoderma lucidum spore and anti-tumor activity of its total polysaccharides]. Yao Xue Xue Bao. 2005;40(4):347-50.
Jiang, Y., Wang, H., Lü, L., & Tian, G. Y. (2005). [Chemistry of polysaccharide Lzps-1 from Ganoderma lucidum spore and anti-tumor activity of its total polysaccharides]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica, 40(4), 347-50.
Jiang Y, et al. [Chemistry of Polysaccharide Lzps-1 From Ganoderma Lucidum Spore and Anti-tumor Activity of Its Total Polysaccharides]. Yao Xue Xue Bao. 2005;40(4):347-50. PubMed PMID: 16011264.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Chemistry of polysaccharide Lzps-1 from Ganoderma lucidum spore and anti-tumor activity of its total polysaccharides]. AU - Jiang,Yan, AU - Wang,Hao, AU - Lü,Long, AU - Tian,Geng-yuan, PY - 2005/7/14/pubmed PY - 2006/8/1/medline PY - 2005/7/14/entrez SP - 347 EP - 50 JF - Yao xue xue bao = Acta pharmaceutica Sinica JO - Yao Xue Xue Bao VL - 40 IS - 4 N2 - AIM: To study the structure and anti-tumor activity of polysaccharide from Ganoderma lucidum spore treated with microwave. METHODS: DEAE-cellulose and Sephadex G-50 column chromatography were used to isolate and purify the polysaccharide whose structure was characterized by using chemical and spectral methods. RESULTS AND CONCLUSION: One polysaccharide, named Lzps-1 was obtained from the water extract, with its molecular weight estimated by HPGPC to be 8000. Its structure was investigated to be glucan. The total polysaccharides, Lzps processed antitumor activity against sarcoma 180 and Lewis lung cancer in mice and enhanced the NK cell activity. Lzps-1 is obtained for the first time from Ganoderma spore Lzps has anti-tumor activity. SN - 0513-4870 UR - https://www.unboundmedicine.com/medline/citation/16011264/[Chemistry_of_polysaccharide_Lzps_1_from_Ganoderma_lucidum_spore_and_anti_tumor_activity_of_its_total_polysaccharides]_ L2 - https://www.lens.org/lens/search/patent/list?q=citation_id:16011264 DB - PRIME DP - Unbound Medicine ER -