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[Perforated peptic ulcer--a 12-year material].
Tidsskr Nor Laegeforen. 2005 Jun 30; 125(13):1822-4.TN

Abstract

BACKGROUND

We aimed to explore patient characteristics, diagnostic and surgical procedures and results of treatment of perforated peptic ulcer at our hospital, and determine prognostic factors for death and postoperative complications.

MATERIAL AND METHODS

Data were collected retrospectively from 102 patients with perforated peptic ulcer identified from a broad case file search of 590 patients from 1992 to 2003. Prognostic factors for dead and post-operative complications were analysed using both uni- and multivariate analyses.

RESULTS

48 men and 54 women, median age 71 (25 - 94) were evaluated. Surgery was performed in 100 patients, 2 received conservative treatment. 55 patients had perforated gastric ulcers (including prepyloric ulcers), and 47 patients had perforated duodenal ulcers. Out of the 100 patients who underwent surgery, 22 died and 39 suffered postoperative complications. By univariate analysis, high age, high ASA score and a long interval between initial symptoms and surgery were significantly associated with death (p < 0.01) and postoperative complications (p < 0.05). By logistic regression, high age (OR 1.1; 95 % CI 1.0 - 1.2; p = 0.04) and high ASA classification (OR 6.7; 95 % CI 1.4 - 33; p = 0.02) predicted death, and high ASA classification predicted postoperative complications (OR 4.2; 95 % CI 1.7 - 10.2; p = 0.002).

INTERPRETATION

Perforated peptic ulcer is a disease with low incidence, high mortality and a high frequency of postoperative complications, mainly determined by the patient's age and ASA classification.

Authors+Show Affiliations

Kirurgisk avdeling, Sykehuset Innlandet Gjøvik, 2819 Gjøvik. havard.forsmo@helse-bergen.noNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

nor

PubMed ID

16012551

Citation

Forsmo, Håvard Mjørud, et al. "[Perforated Peptic Ulcer--a 12-year Material]." Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, vol. 125, no. 13, 2005, pp. 1822-4.
Forsmo HM, Glomsaker T, Vandvik PO. [Perforated peptic ulcer--a 12-year material]. Tidsskr Nor Laegeforen. 2005;125(13):1822-4.
Forsmo, H. M., Glomsaker, T., & Vandvik, P. O. (2005). [Perforated peptic ulcer--a 12-year material]. Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, 125(13), 1822-4.
Forsmo HM, Glomsaker T, Vandvik PO. [Perforated Peptic Ulcer--a 12-year Material]. Tidsskr Nor Laegeforen. 2005 Jun 30;125(13):1822-4. PubMed PMID: 16012551.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Perforated peptic ulcer--a 12-year material]. AU - Forsmo,Håvard Mjørud, AU - Glomsaker,Tom, AU - Vandvik,Per Olav, PY - 2005/7/14/pubmed PY - 2005/7/26/medline PY - 2005/7/14/entrez SP - 1822 EP - 4 JF - Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke JO - Tidsskr Nor Laegeforen VL - 125 IS - 13 N2 - BACKGROUND: We aimed to explore patient characteristics, diagnostic and surgical procedures and results of treatment of perforated peptic ulcer at our hospital, and determine prognostic factors for death and postoperative complications. MATERIAL AND METHODS: Data were collected retrospectively from 102 patients with perforated peptic ulcer identified from a broad case file search of 590 patients from 1992 to 2003. Prognostic factors for dead and post-operative complications were analysed using both uni- and multivariate analyses. RESULTS: 48 men and 54 women, median age 71 (25 - 94) were evaluated. Surgery was performed in 100 patients, 2 received conservative treatment. 55 patients had perforated gastric ulcers (including prepyloric ulcers), and 47 patients had perforated duodenal ulcers. Out of the 100 patients who underwent surgery, 22 died and 39 suffered postoperative complications. By univariate analysis, high age, high ASA score and a long interval between initial symptoms and surgery were significantly associated with death (p < 0.01) and postoperative complications (p < 0.05). By logistic regression, high age (OR 1.1; 95 % CI 1.0 - 1.2; p = 0.04) and high ASA classification (OR 6.7; 95 % CI 1.4 - 33; p = 0.02) predicted death, and high ASA classification predicted postoperative complications (OR 4.2; 95 % CI 1.7 - 10.2; p = 0.002). INTERPRETATION: Perforated peptic ulcer is a disease with low incidence, high mortality and a high frequency of postoperative complications, mainly determined by the patient's age and ASA classification. SN - 0807-7096 UR - https://www.unboundmedicine.com/medline/citation/16012551/[Perforated_peptic_ulcer__a_12_year_material]_ L2 - http://tidsskriftet.no/article/1221957 DB - PRIME DP - Unbound Medicine ER -