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Allele frequencies of the six miniSTR loci in a population from Japan.
Int J Legal Med. 2006 May; 120(3):182-4.IJ

Abstract

Allele frequencies and forensic parameters for the six miniSTR loci D1S1677, D2S441, D4S2364, D10S1248, D14S1434, and D22S1045 were investigated in a sample of 142 unrelated healthy Japanese individuals. The polymerase chain reaction (PCR) products contained within the six loci were less than 119 bp in size. The frequency distributions in the six short tandem repeat (STR) loci showed no deviations from Hardy-Weinberg equilibrium expectations. The accumulated powers of discrimination and power of exclusion for the six loci were 0.999998 and 0.98, respectively. It was thus considered that due to the small PCR products and the moderate degree of polymorphism, analysis with use of the six miniSTR loci was highly beneficial for the forensic analysis of degraded DNA.

Authors+Show Affiliations

Asamura H
Department of Legal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan. asamura@sch.md.shinshu-u.ac.jp
Uchida R
No affiliation info available
Takayanagi K
No affiliation info available
Ota M
No affiliation info available
Fukushima H
No affiliation info available

MeSH

Asian PeopleDNA FingerprintingGene FrequencyGenetics, PopulationHumansJapanMinisatellite RepeatsPolymerase Chain Reaction

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16012828

Citation

Asamura, H, et al. "Allele Frequencies of the Six miniSTR Loci in a Population From Japan." International Journal of Legal Medicine, vol. 120, no. 3, 2006, pp. 182-4.
Asamura H, Uchida R, Takayanagi K, et al. Allele frequencies of the six miniSTR loci in a population from Japan. Int J Legal Med. 2006;120(3):182-4.
Asamura, H., Uchida, R., Takayanagi, K., Ota, M., & Fukushima, H. (2006). Allele frequencies of the six miniSTR loci in a population from Japan. International Journal of Legal Medicine, 120(3), 182-4.
Asamura H, et al. Allele Frequencies of the Six miniSTR Loci in a Population From Japan. Int J Legal Med. 2006;120(3):182-4. PubMed PMID: 16012828.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Allele frequencies of the six miniSTR loci in a population from Japan. AU - Asamura,H, AU - Uchida,R, AU - Takayanagi,K, AU - Ota,M, AU - Fukushima,H, Y1 - 2005/07/13/ PY - 2005/03/31/received PY - 2005/06/14/accepted PY - 2005/7/14/pubmed PY - 2007/5/26/medline PY - 2005/7/14/entrez SP - 182 EP - 4 JF - International journal of legal medicine JO - Int J Legal Med VL - 120 IS - 3 N2 - Allele frequencies and forensic parameters for the six miniSTR loci D1S1677, D2S441, D4S2364, D10S1248, D14S1434, and D22S1045 were investigated in a sample of 142 unrelated healthy Japanese individuals. The polymerase chain reaction (PCR) products contained within the six loci were less than 119 bp in size. The frequency distributions in the six short tandem repeat (STR) loci showed no deviations from Hardy-Weinberg equilibrium expectations. The accumulated powers of discrimination and power of exclusion for the six loci were 0.999998 and 0.98, respectively. It was thus considered that due to the small PCR products and the moderate degree of polymorphism, analysis with use of the six miniSTR loci was highly beneficial for the forensic analysis of degraded DNA. SN - 0937-9827 UR - https://www.unboundmedicine.com/medline/citation/16012828/Allele_frequencies_of_the_six_miniSTR_loci_in_a_population_from_Japan_ DB - PRIME DP - Unbound Medicine ER -