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Plasmid mediated multidrug resistance in Salmonella typhi.
Indian J Med Res. 1992 Mar; 95:66-7.IJ

Abstract

Between September 1989 and February 1991, strains of S. typhi showing multiple drug resistance were isolated from blood cultures of patients with typhoid fever. A total of 283 isolates were obtained over a period of 18 months. Forty four (11%) of these isolates were resistant to chloramphenicol, ampicillin, co-trimoxazole and tetracycline, the first three being drugs currently used in treating typhoid fever. Forty of the 44 multi-resistant strains tested showed transfer of resistance 'en block' to recipient Escherichia coli K 12 (J62-2). All 44 multi-resistant strains were sensitive to ciprofloxacin and ofloxacin. Since the resistance is plasmid-mediated, the problem is likely to get aggravated.

Authors+Show Affiliations

Department of Microbiology, Christian Medical College Hospital, Vellore.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1601471

Citation

Jesudason, M V., and T J. John. "Plasmid Mediated Multidrug Resistance in Salmonella Typhi." The Indian Journal of Medical Research, vol. 95, 1992, pp. 66-7.
Jesudason MV, John TJ. Plasmid mediated multidrug resistance in Salmonella typhi. Indian J Med Res. 1992;95:66-7.
Jesudason, M. V., & John, T. J. (1992). Plasmid mediated multidrug resistance in Salmonella typhi. The Indian Journal of Medical Research, 95, 66-7.
Jesudason MV, John TJ. Plasmid Mediated Multidrug Resistance in Salmonella Typhi. Indian J Med Res. 1992;95:66-7. PubMed PMID: 1601471.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Plasmid mediated multidrug resistance in Salmonella typhi. AU - Jesudason,M V, AU - John,T J, PY - 1992/3/1/pubmed PY - 1992/3/1/medline PY - 1992/3/1/entrez SP - 66 EP - 7 JF - The Indian journal of medical research JO - Indian J Med Res VL - 95 N2 - Between September 1989 and February 1991, strains of S. typhi showing multiple drug resistance were isolated from blood cultures of patients with typhoid fever. A total of 283 isolates were obtained over a period of 18 months. Forty four (11%) of these isolates were resistant to chloramphenicol, ampicillin, co-trimoxazole and tetracycline, the first three being drugs currently used in treating typhoid fever. Forty of the 44 multi-resistant strains tested showed transfer of resistance 'en block' to recipient Escherichia coli K 12 (J62-2). All 44 multi-resistant strains were sensitive to ciprofloxacin and ofloxacin. Since the resistance is plasmid-mediated, the problem is likely to get aggravated. SN - 0971-5916 UR - https://www.unboundmedicine.com/medline/citation/1601471/Plasmid_mediated_multidrug_resistance_in_Salmonella_typhi_ DB - PRIME DP - Unbound Medicine ER -