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Effect on sexual life--a comparison between tibolone and continuous combined conjugated equine estrogens and medroxyprogesterone acetate.
Gynecol Endocrinol. 2005 Apr; 20(4):209-12.GE

Abstract

OBJECTIVES

To compare the effects of tibolone 2.5 mg with those of continuous combined conjugated equine estrogens 0.625 mg/day and medroxyprogesterone acetate 5 mg/day (CEE/MPA) on sexual life in postmenopausal women.

METHODS

Eighty women were randomized to treatment with either tibolone or continuous combined CEE/MPA. Subjects were asked about sexual desire, sexual excitement, sexual arousal, orgasm capacity, vaginal lubrication during sexual activity and dyspareunia before and after the treatment.

RESULTS

After 6 months of treatment, a total of 72 women completed the study. When tibolone was compared with continuous combined CEE/MPA, significantly higher scores were found for the items assessing sexual desire, sexual excitement, intercourse frequency and vaginal dryness (p < 0.05).

CONCLUSION

This study indicates that both tibolone and continuous combined CEE/MPA treatment were associated with significant improvements in sexual function in postmenopausal women. However, tibolone treatment improved sexual function to a greater extent than continuous combined CEE/MPA.

Authors+Show Affiliations

Zübeyde Hanim Maternity Hospital, Telsizler, Ankara, Turkey. uygurdc@superonline.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

16019363

Citation

Uygur, Dilek, et al. "Effect On Sexual Life--a Comparison Between Tibolone and Continuous Combined Conjugated Equine Estrogens and Medroxyprogesterone Acetate." Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology, vol. 20, no. 4, 2005, pp. 209-12.
Uygur D, Yeşildaglar N, Erkaya S. Effect on sexual life--a comparison between tibolone and continuous combined conjugated equine estrogens and medroxyprogesterone acetate. Gynecol Endocrinol. 2005;20(4):209-12.
Uygur, D., Yeşildaglar, N., & Erkaya, S. (2005). Effect on sexual life--a comparison between tibolone and continuous combined conjugated equine estrogens and medroxyprogesterone acetate. Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology, 20(4), 209-12.
Uygur D, Yeşildaglar N, Erkaya S. Effect On Sexual Life--a Comparison Between Tibolone and Continuous Combined Conjugated Equine Estrogens and Medroxyprogesterone Acetate. Gynecol Endocrinol. 2005;20(4):209-12. PubMed PMID: 16019363.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect on sexual life--a comparison between tibolone and continuous combined conjugated equine estrogens and medroxyprogesterone acetate. AU - Uygur,Dilek, AU - Yeşildaglar,Narter, AU - Erkaya,Salim, PY - 2005/7/16/pubmed PY - 2005/9/30/medline PY - 2005/7/16/entrez SP - 209 EP - 12 JF - Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology JO - Gynecol Endocrinol VL - 20 IS - 4 N2 - OBJECTIVES: To compare the effects of tibolone 2.5 mg with those of continuous combined conjugated equine estrogens 0.625 mg/day and medroxyprogesterone acetate 5 mg/day (CEE/MPA) on sexual life in postmenopausal women. METHODS: Eighty women were randomized to treatment with either tibolone or continuous combined CEE/MPA. Subjects were asked about sexual desire, sexual excitement, sexual arousal, orgasm capacity, vaginal lubrication during sexual activity and dyspareunia before and after the treatment. RESULTS: After 6 months of treatment, a total of 72 women completed the study. When tibolone was compared with continuous combined CEE/MPA, significantly higher scores were found for the items assessing sexual desire, sexual excitement, intercourse frequency and vaginal dryness (p < 0.05). CONCLUSION: This study indicates that both tibolone and continuous combined CEE/MPA treatment were associated with significant improvements in sexual function in postmenopausal women. However, tibolone treatment improved sexual function to a greater extent than continuous combined CEE/MPA. SN - 0951-3590 UR - https://www.unboundmedicine.com/medline/citation/16019363/Effect_on_sexual_life__a_comparison_between_tibolone_and_continuous_combined_conjugated_equine_estrogens_and_medroxyprogesterone_acetate_ L2 - https://www.tandfonline.com/doi/full/10.1080/09513590400027240 DB - PRIME DP - Unbound Medicine ER -