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Optimizing oral nutritional drink supplementation in patients with chronic obstructive pulmonary disease.
Br J Nutr 2005; 93(6):965-71BJ

Abstract

Nutritional support is indicated in some patients with chronic obstructive pulmonary disease to restore nutritional status and improve functional capacity. However, the efficacy of nutritional supplements is sometimes disappointing, partly owing to a compensatory drop in habitual food intake. We retrospectively studied the effect of nutritional drink supplements, differing in portion size and energy content, on weight gain and body composition. Thirty-nine patients with stable chronic obstructive pulmonary disease, participating in an 8-week pulmonary rehabilitation programme and eligible for nutritional support, were studied. Group A (n 19) received three portions of 125 ml (2380 kJ), whereas group B (n 20) received three portions of 200 ml (3350 kJ) daily. The macronutrient composition of the regimens was similar (20 % protein, 60 % carbohydrates and 20 % fat). Lung function, body weight, body composition (by bio-electrical impedance analysis), habitual dietary intake (by dietary history) and resting energy expenditure (by ventilated hood) were determined. Weight gain was compared with expected weight as predicted by a computer simulation model. Although patients in both groups significantly increased in weight, this increase was higher in group A (A, 3.3 (sd 1.9) kg; B, 2.0 (sd 1.2) kg; P=0.019), while receiving less energy. The observed weight gain in group A was similar to that expected, but in group B it was lower than expected (P<0.001). In both groups, fat-free mass and fat mass were gained in a ratio of 2:1, fat-free mass increasing primarily during the first 4 weeks. This study illustrates that there might be an optimum for the portion size of nutritional drink supplements in chronic obstructive pulmonary disease and that more is not always better.

Authors+Show Affiliations

Department of Respiratory Medicine, University Hospital Maastricht, The Netherlands. r.broekhuizen@pul.unimaas.nlNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16022768

Citation

Broekhuizen, Roelinka, et al. "Optimizing Oral Nutritional Drink Supplementation in Patients With Chronic Obstructive Pulmonary Disease." The British Journal of Nutrition, vol. 93, no. 6, 2005, pp. 965-71.
Broekhuizen R, Creutzberg EC, Weling-Scheepers CA, et al. Optimizing oral nutritional drink supplementation in patients with chronic obstructive pulmonary disease. Br J Nutr. 2005;93(6):965-71.
Broekhuizen, R., Creutzberg, E. C., Weling-Scheepers, C. A., Wouters, E. F., & Schols, A. M. (2005). Optimizing oral nutritional drink supplementation in patients with chronic obstructive pulmonary disease. The British Journal of Nutrition, 93(6), pp. 965-71.
Broekhuizen R, et al. Optimizing Oral Nutritional Drink Supplementation in Patients With Chronic Obstructive Pulmonary Disease. Br J Nutr. 2005;93(6):965-71. PubMed PMID: 16022768.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Optimizing oral nutritional drink supplementation in patients with chronic obstructive pulmonary disease. AU - Broekhuizen,Roelinka, AU - Creutzberg,Eva C, AU - Weling-Scheepers,Clarie A P M, AU - Wouters,Emiel F M, AU - Schols,Annemie M W J, PY - 2005/7/19/pubmed PY - 2005/9/7/medline PY - 2005/7/19/entrez SP - 965 EP - 71 JF - The British journal of nutrition JO - Br. J. Nutr. VL - 93 IS - 6 N2 - Nutritional support is indicated in some patients with chronic obstructive pulmonary disease to restore nutritional status and improve functional capacity. However, the efficacy of nutritional supplements is sometimes disappointing, partly owing to a compensatory drop in habitual food intake. We retrospectively studied the effect of nutritional drink supplements, differing in portion size and energy content, on weight gain and body composition. Thirty-nine patients with stable chronic obstructive pulmonary disease, participating in an 8-week pulmonary rehabilitation programme and eligible for nutritional support, were studied. Group A (n 19) received three portions of 125 ml (2380 kJ), whereas group B (n 20) received three portions of 200 ml (3350 kJ) daily. The macronutrient composition of the regimens was similar (20 % protein, 60 % carbohydrates and 20 % fat). Lung function, body weight, body composition (by bio-electrical impedance analysis), habitual dietary intake (by dietary history) and resting energy expenditure (by ventilated hood) were determined. Weight gain was compared with expected weight as predicted by a computer simulation model. Although patients in both groups significantly increased in weight, this increase was higher in group A (A, 3.3 (sd 1.9) kg; B, 2.0 (sd 1.2) kg; P=0.019), while receiving less energy. The observed weight gain in group A was similar to that expected, but in group B it was lower than expected (P<0.001). In both groups, fat-free mass and fat mass were gained in a ratio of 2:1, fat-free mass increasing primarily during the first 4 weeks. This study illustrates that there might be an optimum for the portion size of nutritional drink supplements in chronic obstructive pulmonary disease and that more is not always better. SN - 0007-1145 UR - https://www.unboundmedicine.com/medline/citation/16022768/Optimizing_oral_nutritional_drink_supplementation_in_patients_with_chronic_obstructive_pulmonary_disease_ L2 - https://www.cambridge.org/core/product/identifier/S0007114505001443/type/journal_article DB - PRIME DP - Unbound Medicine ER -