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C-terminal Pro-Gly-Pro tripeptide in contrast to full-length neuropeptide semax exhibits no neuroprotective effect in experimental cerebral ischemia.
Bull Exp Biol Med. 2005 Apr; 139(4):421-3.BE

Abstract

The C-terminal fragment Pro-Gly-Pro of semax does not modulate the development of symptoms of neurological deficiency and mortality in rats with incomplete global cerebral ischemia. Hence, previously revealed neuroprotective effects of semax are mainly determined by corticotropin ACTH4-7 fragment.

Authors+Show Affiliations

Fadyukova OE
Faculty of Fundamental Medicine; Biological Faculty, M. V. Lomo-nosov Moscow State University, Russia. olevfa@fbm.msu.ru
Kadi A
No affiliation info available
Bai O
No affiliation info available
Andzhusheva GM
No affiliation info available
Koshelev VB
No affiliation info available

MeSH

AnimalsBrain IschemiaNeuroprotective AgentsOligopeptidesProlineRats

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16027870

Citation

Fadyukova, O E., et al. "C-terminal Pro-Gly-Pro Tripeptide in Contrast to Full-length Neuropeptide Semax Exhibits No Neuroprotective Effect in Experimental Cerebral Ischemia." Bulletin of Experimental Biology and Medicine, vol. 139, no. 4, 2005, pp. 421-3.
Fadyukova OE, Kadi A, Bai O, et al. C-terminal Pro-Gly-Pro tripeptide in contrast to full-length neuropeptide semax exhibits no neuroprotective effect in experimental cerebral ischemia. Bull Exp Biol Med. 2005;139(4):421-3.
Fadyukova, O. E., Kadi, A., Bai, O., Andzhusheva, G. M., & Koshelev, V. B. (2005). C-terminal Pro-Gly-Pro tripeptide in contrast to full-length neuropeptide semax exhibits no neuroprotective effect in experimental cerebral ischemia. Bulletin of Experimental Biology and Medicine, 139(4), 421-3.
Fadyukova OE, et al. C-terminal Pro-Gly-Pro Tripeptide in Contrast to Full-length Neuropeptide Semax Exhibits No Neuroprotective Effect in Experimental Cerebral Ischemia. Bull Exp Biol Med. 2005;139(4):421-3. PubMed PMID: 16027870.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - C-terminal Pro-Gly-Pro tripeptide in contrast to full-length neuropeptide semax exhibits no neuroprotective effect in experimental cerebral ischemia. AU - Fadyukova,O E, AU - Kadi,A, AU - Bai,Ou, AU - Andzhusheva,G M, AU - Koshelev,V B, PY - 2005/7/20/pubmed PY - 2006/2/17/medline PY - 2005/7/20/entrez SP - 421 EP - 3 JF - Bulletin of experimental biology and medicine JO - Bull Exp Biol Med VL - 139 IS - 4 N2 - The C-terminal fragment Pro-Gly-Pro of semax does not modulate the development of symptoms of neurological deficiency and mortality in rats with incomplete global cerebral ischemia. Hence, previously revealed neuroprotective effects of semax are mainly determined by corticotropin ACTH4-7 fragment. SN - 0007-4888 UR - https://www.unboundmedicine.com/medline/citation/16027870/C_terminal_Pro_Gly_Pro_tripeptide_in_contrast_to_full_length_neuropeptide_semax_exhibits_no_neuroprotective_effect_in_experimental_cerebral_ischemia_ DB - PRIME DP - Unbound Medicine ER -