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Phenolic antioxidants from the heartwood of Acacia confusa.
J Agric Food Chem. 2005 Jul 27; 53(15):5917-21.JA

Abstract

In the present study, the ethanolic extracts from the heartwood of Acacia confusa, a species indigenous to Taiwan, exhibit strong antioxidant effects. Among all the fractions from ethanolic extracts of heartwood, the EtOAc soluble fraction exhibits the best antioxidant activity. The 80% 1,1-diphenyl-2-picrylhydrazyl radical inhibitory activity by the EtOAc extract was observed at a concentration of 5 mug/mL, and at the same dosage there was a similar free radical scavenging activity for (-)-ascorbic acid and (+)-catechin, both of which are well-known antioxidants. In addition, the EtOAc extract also protects PhiX174 supercoiled DNA against strand scission induced by hydroxyl radical. Furthermore, following by column chromatography and reverse-phase high-performance liquid chromatorgrapy, 10 pure phenolic compounds, including three major antioxidants (3,7,8,3',4'-pentahydroxyflavone, 7,8,3',4'-tetrahydroxy-3-methoxyflavone, and 3,4,2',3',4'-pentahydroxy-trans-chalcone) and a new flavonoid (3,7,8,3'-tetrahydroxy-4'-methoxyflavone), were isolated from the ethanolic extracts of A. confusa heartwood.

Authors+Show Affiliations

School of Forestry and Resource Conservation, National Taiwan University, Taipei 106, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16028974

Citation

Wu, Jyh-Horng, et al. "Phenolic Antioxidants From the Heartwood of Acacia Confusa." Journal of Agricultural and Food Chemistry, vol. 53, no. 15, 2005, pp. 5917-21.
Wu JH, Tung YT, Wang SY, et al. Phenolic antioxidants from the heartwood of Acacia confusa. J Agric Food Chem. 2005;53(15):5917-21.
Wu, J. H., Tung, Y. T., Wang, S. Y., Shyur, L. F., Kuo, Y. H., & Chang, S. T. (2005). Phenolic antioxidants from the heartwood of Acacia confusa. Journal of Agricultural and Food Chemistry, 53(15), 5917-21.
Wu JH, et al. Phenolic Antioxidants From the Heartwood of Acacia Confusa. J Agric Food Chem. 2005 Jul 27;53(15):5917-21. PubMed PMID: 16028974.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Phenolic antioxidants from the heartwood of Acacia confusa. AU - Wu,Jyh-Horng, AU - Tung,Yu-Tang, AU - Wang,Sheng-Yang, AU - Shyur,Lie-Fen, AU - Kuo,Yueh-Hsiung, AU - Chang,Shang-Tzen, PY - 2005/7/21/pubmed PY - 2005/9/2/medline PY - 2005/7/21/entrez SP - 5917 EP - 21 JF - Journal of agricultural and food chemistry JO - J. Agric. Food Chem. VL - 53 IS - 15 N2 - In the present study, the ethanolic extracts from the heartwood of Acacia confusa, a species indigenous to Taiwan, exhibit strong antioxidant effects. Among all the fractions from ethanolic extracts of heartwood, the EtOAc soluble fraction exhibits the best antioxidant activity. The 80% 1,1-diphenyl-2-picrylhydrazyl radical inhibitory activity by the EtOAc extract was observed at a concentration of 5 mug/mL, and at the same dosage there was a similar free radical scavenging activity for (-)-ascorbic acid and (+)-catechin, both of which are well-known antioxidants. In addition, the EtOAc extract also protects PhiX174 supercoiled DNA against strand scission induced by hydroxyl radical. Furthermore, following by column chromatography and reverse-phase high-performance liquid chromatorgrapy, 10 pure phenolic compounds, including three major antioxidants (3,7,8,3',4'-pentahydroxyflavone, 7,8,3',4'-tetrahydroxy-3-methoxyflavone, and 3,4,2',3',4'-pentahydroxy-trans-chalcone) and a new flavonoid (3,7,8,3'-tetrahydroxy-4'-methoxyflavone), were isolated from the ethanolic extracts of A. confusa heartwood. SN - 0021-8561 UR - https://www.unboundmedicine.com/medline/citation/16028974/Phenolic_antioxidants_from_the_heartwood_of_Acacia_confusa_ L2 - https://dx.doi.org/10.1021/jf050550m DB - PRIME DP - Unbound Medicine ER -