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Age-specific reference levels of serum prostate-specific antigen and prostate volume in healthy Arab men.
BJU Int. 2005 Aug; 96(3):308-12.BI

Abstract

OBJECTIVE; To determine age-specific reference ranges for serum prostate-specific antigen (PSA) concentration and prostate volumes in a population of healthy Arab men.

SUBJECTS AND METHODS

Blood samples were taken from 396 healthy Arab men (from Kuwait and Oman) aged 15-79 years and from across the social spectrum. Men aged >40 years had a digital rectal examination and transrectal ultrasonography of the prostate to determine prostate volume. The serum PSA level was measured using commercial kits, and age-specific ranges for PSA levels and prostate volume determined.

RESULTS

The serum PSA ranges (ng/mL) for each age range in Arab men were: 40-49 years, 0-0.9; 60-69, 0-2.7; 70-79, 0-5.5 ng/mL; the respective prostate volumes were 8-22, 9-30 and 10-33 mL. The serum PSA level and prostate volume correlated with age (P < 0.001). Arab men had lower serum PSA levels and prostate volumes than those reported for Caucasians, but similar to those reported for Asians (Japanese and Chinese).

CONCLUSION

These results indicate that Arab men have lower PSA levels and prostate volumes than Caucasians. The levels are slightly lower than those reported in the Japanese and, as in the Japanese, low PSA levels and small prostate volumes might be related to the low incidence of clinical prostate cancer in Arab men.

Authors+Show Affiliations

Department of Surgery, Division of Urology, Faculty of Medicine, Kuwait University, Kuwait. ekehinde@hsc.edu.kwNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16042719

Citation

Kehinde, Elijah O., et al. "Age-specific Reference Levels of Serum Prostate-specific Antigen and Prostate Volume in Healthy Arab Men." BJU International, vol. 96, no. 3, 2005, pp. 308-12.
Kehinde EO, Mojiminiyi OA, Sheikh M, et al. Age-specific reference levels of serum prostate-specific antigen and prostate volume in healthy Arab men. BJU Int. 2005;96(3):308-12.
Kehinde, E. O., Mojiminiyi, O. A., Sheikh, M., Al-Awadi, K. A., Daar, A. S., Al-Hunayan, A., Anim, J. T., & Al-Sumait, A. A. (2005). Age-specific reference levels of serum prostate-specific antigen and prostate volume in healthy Arab men. BJU International, 96(3), 308-12.
Kehinde EO, et al. Age-specific Reference Levels of Serum Prostate-specific Antigen and Prostate Volume in Healthy Arab Men. BJU Int. 2005;96(3):308-12. PubMed PMID: 16042719.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Age-specific reference levels of serum prostate-specific antigen and prostate volume in healthy Arab men. AU - Kehinde,Elijah O, AU - Mojiminiyi,Olusegun A, AU - Sheikh,Mehraj, AU - Al-Awadi,Kaleel A, AU - Daar,Abdallah S, AU - Al-Hunayan,Adel, AU - Anim,Jehoram T, AU - Al-Sumait,Aisha A, PY - 2005/7/27/pubmed PY - 2005/9/13/medline PY - 2005/7/27/entrez SP - 308 EP - 12 JF - BJU international JO - BJU Int VL - 96 IS - 3 N2 - UNLABELLED: OBJECTIVE; To determine age-specific reference ranges for serum prostate-specific antigen (PSA) concentration and prostate volumes in a population of healthy Arab men. SUBJECTS AND METHODS: Blood samples were taken from 396 healthy Arab men (from Kuwait and Oman) aged 15-79 years and from across the social spectrum. Men aged >40 years had a digital rectal examination and transrectal ultrasonography of the prostate to determine prostate volume. The serum PSA level was measured using commercial kits, and age-specific ranges for PSA levels and prostate volume determined. RESULTS: The serum PSA ranges (ng/mL) for each age range in Arab men were: 40-49 years, 0-0.9; 60-69, 0-2.7; 70-79, 0-5.5 ng/mL; the respective prostate volumes were 8-22, 9-30 and 10-33 mL. The serum PSA level and prostate volume correlated with age (P < 0.001). Arab men had lower serum PSA levels and prostate volumes than those reported for Caucasians, but similar to those reported for Asians (Japanese and Chinese). CONCLUSION: These results indicate that Arab men have lower PSA levels and prostate volumes than Caucasians. The levels are slightly lower than those reported in the Japanese and, as in the Japanese, low PSA levels and small prostate volumes might be related to the low incidence of clinical prostate cancer in Arab men. SN - 1464-4096 UR - https://www.unboundmedicine.com/medline/citation/16042719/Age_specific_reference_levels_of_serum_prostate_specific_antigen_and_prostate_volume_in_healthy_Arab_men_ L2 - https://doi.org/10.1111/j.1464-410X.2005.05620.x DB - PRIME DP - Unbound Medicine ER -