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How do urinary diaries of women with an overactive bladder differ from those of asymptomatic controls?
BJU Int. 2005 Aug; 96(3):365-7.BI

Abstract

OBJECTIVE

To quantify clinically important differences in common diary variables between asymptomatic controls and women with symptoms of overactive bladder (OAB), controlling for the effects of age and race.

PATIENTS, SUBJECTS AND METHODS

The 24-h urinary diaries of 49 women with symptoms of OAB were compared to those of age- and race-matched asymptomatic controls. Control subjects did not have a physical examination.

RESULTS

The 49 patients with OAB symptoms had a median (range) age of 51 (20-85) years, a body mass index of 25 (17-46) kg/m(2) and a parity of 2 (0-5). The median number of voids was significantly greater in women with OAB than asymptomatic controls (P < 0.001). The median value for mean voided volume was significantly lower in women with OAB than asymptomatic controls (P = 0.014). There was no difference in the maximum voided volume, total voided volume, daytime or night-time diuresis rates, voids per litre intake, or total fluid intake.

CONCLUSIONS

This preliminary study suggests that a median reduction of three voids/24 h and an increase of 70 mL in the mean voided volume might be clinically important goals in therapeutic trials for treating OAB symptoms. This remains to be confirmed by further studies linking improvements in quality of life and the overall impression of bladder health with these quantitative diary variable changes.

Authors+Show Affiliations

Division of Female Pelvic Medicine and Reconstructive Surgery, Loyola University Medical Center, Maywood, IL 60153, USA. mfitzg8@lumc.eduNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16042731

Citation

Fitzgerald, Mary P., et al. "How Do Urinary Diaries of Women With an Overactive Bladder Differ From Those of Asymptomatic Controls?" BJU International, vol. 96, no. 3, 2005, pp. 365-7.
Fitzgerald MP, Ayuste D, Brubaker L. How do urinary diaries of women with an overactive bladder differ from those of asymptomatic controls? BJU Int. 2005;96(3):365-7.
Fitzgerald, M. P., Ayuste, D., & Brubaker, L. (2005). How do urinary diaries of women with an overactive bladder differ from those of asymptomatic controls? BJU International, 96(3), 365-7.
Fitzgerald MP, Ayuste D, Brubaker L. How Do Urinary Diaries of Women With an Overactive Bladder Differ From Those of Asymptomatic Controls. BJU Int. 2005;96(3):365-7. PubMed PMID: 16042731.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - How do urinary diaries of women with an overactive bladder differ from those of asymptomatic controls? AU - Fitzgerald,Mary P, AU - Ayuste,Deborah, AU - Brubaker,Linda, PY - 2005/7/27/pubmed PY - 2005/9/13/medline PY - 2005/7/27/entrez SP - 365 EP - 7 JF - BJU international JO - BJU Int VL - 96 IS - 3 N2 - OBJECTIVE: To quantify clinically important differences in common diary variables between asymptomatic controls and women with symptoms of overactive bladder (OAB), controlling for the effects of age and race. PATIENTS, SUBJECTS AND METHODS: The 24-h urinary diaries of 49 women with symptoms of OAB were compared to those of age- and race-matched asymptomatic controls. Control subjects did not have a physical examination. RESULTS: The 49 patients with OAB symptoms had a median (range) age of 51 (20-85) years, a body mass index of 25 (17-46) kg/m(2) and a parity of 2 (0-5). The median number of voids was significantly greater in women with OAB than asymptomatic controls (P < 0.001). The median value for mean voided volume was significantly lower in women with OAB than asymptomatic controls (P = 0.014). There was no difference in the maximum voided volume, total voided volume, daytime or night-time diuresis rates, voids per litre intake, or total fluid intake. CONCLUSIONS: This preliminary study suggests that a median reduction of three voids/24 h and an increase of 70 mL in the mean voided volume might be clinically important goals in therapeutic trials for treating OAB symptoms. This remains to be confirmed by further studies linking improvements in quality of life and the overall impression of bladder health with these quantitative diary variable changes. SN - 1464-4096 UR - https://www.unboundmedicine.com/medline/citation/16042731/How_do_urinary_diaries_of_women_with_an_overactive_bladder_differ_from_those_of_asymptomatic_controls L2 - https://doi.org/10.1111/j.1464-410X.2005.05632.x DB - PRIME DP - Unbound Medicine ER -