Tags

Type your tag names separated by a space and hit enter

Brain activation of spider phobics towards disorder-relevant, generally disgust- and fear-inducing pictures.
Neurosci Lett. 2005 Nov 04; 388(1):1-6.NL

Abstract

The present functional magnetic resonance imaging study investigated the fear and disgust reactivity of patients suffering from spider phobia. Ten phobics and 13 control subjects were scanned while viewing alternating blocks of phobia-relevant, generally fear-inducing, disgust-inducing and affectively neutral pictures. The patient group rated the spider pictures as being more disgust and fear evoking than the control group, and showed greater activation of the visual association cortex, the amygdalae, the right dorsolateral prefrontal cortex and the right hippocampus. Specific phobia-related activation occurred in the supplementary motor area. The patients also showed greater amygdala activation during the presentation of generally disgust- and fear-inducing pictures. This points to an elevated sensitivity to repulsive and threatening stimuli in spider phobics and implicates the amygdala as a crucial neural substrate.

Authors+Show Affiliations

Schienle A
Bender Institute of Neuroimaging, University of Giessen, Otto-Behaghel-Strasse 10, 35394 Giessen, Germany. Anne.Schienle@psychol.uni-giessen.de
Schäfer A
No affiliation info available
Walter B
No affiliation info available
Stark R
No affiliation info available
Vaitl D
No affiliation info available

MeSH

AdultAmygdalaAnimalsBrainBrain MappingFearFemaleFunctional LateralityHippocampusHumansMagnetic Resonance ImagingNeural PathwaysPhobic DisordersPhotic StimulationPrefrontal CortexSex FactorsSpiders

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16046064

Citation

Schienle, Anne, et al. "Brain Activation of Spider Phobics Towards Disorder-relevant, Generally Disgust- and Fear-inducing Pictures." Neuroscience Letters, vol. 388, no. 1, 2005, pp. 1-6.
Schienle A, Schäfer A, Walter B, et al. Brain activation of spider phobics towards disorder-relevant, generally disgust- and fear-inducing pictures. Neurosci Lett. 2005;388(1):1-6.
Schienle, A., Schäfer, A., Walter, B., Stark, R., & Vaitl, D. (2005). Brain activation of spider phobics towards disorder-relevant, generally disgust- and fear-inducing pictures. Neuroscience Letters, 388(1), 1-6.
Schienle A, et al. Brain Activation of Spider Phobics Towards Disorder-relevant, Generally Disgust- and Fear-inducing Pictures. Neurosci Lett. 2005 Nov 4;388(1):1-6. PubMed PMID: 16046064.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Brain activation of spider phobics towards disorder-relevant, generally disgust- and fear-inducing pictures. AU - Schienle,Anne, AU - Schäfer,Axel, AU - Walter,Bertram, AU - Stark,Rudolf, AU - Vaitl,Dieter, PY - 2004/11/23/received PY - 2005/06/06/revised PY - 2005/06/07/accepted PY - 2005/7/28/pubmed PY - 2005/10/29/medline PY - 2005/7/28/entrez SP - 1 EP - 6 JF - Neuroscience letters JO - Neurosci Lett VL - 388 IS - 1 N2 - The present functional magnetic resonance imaging study investigated the fear and disgust reactivity of patients suffering from spider phobia. Ten phobics and 13 control subjects were scanned while viewing alternating blocks of phobia-relevant, generally fear-inducing, disgust-inducing and affectively neutral pictures. The patient group rated the spider pictures as being more disgust and fear evoking than the control group, and showed greater activation of the visual association cortex, the amygdalae, the right dorsolateral prefrontal cortex and the right hippocampus. Specific phobia-related activation occurred in the supplementary motor area. The patients also showed greater amygdala activation during the presentation of generally disgust- and fear-inducing pictures. This points to an elevated sensitivity to repulsive and threatening stimuli in spider phobics and implicates the amygdala as a crucial neural substrate. SN - 0304-3940 UR - https://www.unboundmedicine.com/medline/citation/16046064/Brain_activation_of_spider_phobics_towards_disorder_relevant_generally_disgust__and_fear_inducing_pictures_ DB - PRIME DP - Unbound Medicine ER -