Abstract
A proposal by Wald and Law (2003) for a single pill containing a statin, three half-dose antihypertensives, aspirin, and folic acid, met with a storm of controversy and seemed to have been relegated as much to the fanciful as to the accolades it might have deserved. The benefits such a Polypill could confer on people age 55+y were to reduce both cardiovascular and stroke events by 80% or more. Considering the daunting and, at best, slow process of changing the same risk factors through health promotion interventions on food policy, dietary and physical activity behaviors, and urban planning to make less prevalent the sedentary lifestyles developed over decades, the argument here is to view the Polypill as a harm reduction strategy that would complement health promotion, as Nicotine Replacement Therapy did for tobacco control, seat belts did for traffic injuries, and needle exchange programs did for secondary complications of injection drug use.
TY - JOUR
T1 - Prospects and possible pitfalls of a preventive Polypill: confessions of a health promotion convert.
A1 - Green,L W,
PY - 2005/7/30/pubmed
PY - 2005/10/29/medline
PY - 2005/7/30/entrez
SP - S4-8; discussion S9
JF - European journal of clinical nutrition
JO - Eur J Clin Nutr
VL - 59 Suppl 1
N2 - A proposal by Wald and Law (2003) for a single pill containing a statin, three half-dose antihypertensives, aspirin, and folic acid, met with a storm of controversy and seemed to have been relegated as much to the fanciful as to the accolades it might have deserved. The benefits such a Polypill could confer on people age 55+y were to reduce both cardiovascular and stroke events by 80% or more. Considering the daunting and, at best, slow process of changing the same risk factors through health promotion interventions on food policy, dietary and physical activity behaviors, and urban planning to make less prevalent the sedentary lifestyles developed over decades, the argument here is to view the Polypill as a harm reduction strategy that would complement health promotion, as Nicotine Replacement Therapy did for tobacco control, seat belts did for traffic injuries, and needle exchange programs did for secondary complications of injection drug use.
SN - 0954-3007
UR - https://www.unboundmedicine.com/medline/citation/16052194/Prospects_and_possible_pitfalls_of_a_preventive_Polypill:_confessions_of_a_health_promotion_convert_
DB - PRIME
DP - Unbound Medicine
ER -
