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Studies on the constituents of Juglans species. I. Structural determination of (4S)- and (4R)-4-hydroxy-alpha-tetralone derivatives from the fruit of Juglans mandshurica MAXIM. var. sieboldiana MAKINO.
Chem Pharm Bull (Tokyo). 2005 Aug; 53(8):934-7.CP

Abstract

Four enantiomerically pure new alpha-tetralones, (4S)- and (4R)-5-hydroxy-4-methoxy-alpha-tetralones and (4S)- and (4R)-5,8-dihydroxy-4-methoxy-alpha-tetralones were isolated, together with five known ones, (4S)- and (4R)-4,8-dihydroxy-alpha-tetralones, (4S)-4,8-dihydroxy-5-methoxy-alpha-tetralone and (4S)- and (4R)-4-hydroxy-alpha-tetralones, from the fruit of Juglans mandshurica MAXIM. var. sieboldiana MAKINO. Their structures were established on the basis of spectral analysis. To the best of our knowledge, this is the first isolation of the (4R)-4-hydroxy-alpha-tetralone derivative from Juglans species.

Authors+Show Affiliations

Machida K
Tohoku Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai, Miyagi 981-8558, Japan.
Matsuoka E
No affiliation info available
Kasahara T
No affiliation info available
Kikuchi M
No affiliation info available

MeSH

Chromatography, High Pressure LiquidJuglansMolecular StructureSpectrum AnalysisTetralones

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16079523

Citation

Machida, Koichi, et al. "Studies On the Constituents of Juglans Species. I. Structural Determination of (4S)- and (4R)-4-hydroxy-alpha-tetralone Derivatives From the Fruit of Juglans Mandshurica MAXIM. Var. Sieboldiana MAKINO." Chemical & Pharmaceutical Bulletin, vol. 53, no. 8, 2005, pp. 934-7.
Machida K, Matsuoka E, Kasahara T, et al. Studies on the constituents of Juglans species. I. Structural determination of (4S)- and (4R)-4-hydroxy-alpha-tetralone derivatives from the fruit of Juglans mandshurica MAXIM. var. sieboldiana MAKINO. Chem Pharm Bull (Tokyo). 2005;53(8):934-7.
Machida, K., Matsuoka, E., Kasahara, T., & Kikuchi, M. (2005). Studies on the constituents of Juglans species. I. Structural determination of (4S)- and (4R)-4-hydroxy-alpha-tetralone derivatives from the fruit of Juglans mandshurica MAXIM. var. sieboldiana MAKINO. Chemical & Pharmaceutical Bulletin, 53(8), 934-7.
Machida K, et al. Studies On the Constituents of Juglans Species. I. Structural Determination of (4S)- and (4R)-4-hydroxy-alpha-tetralone Derivatives From the Fruit of Juglans Mandshurica MAXIM. Var. Sieboldiana MAKINO. Chem Pharm Bull (Tokyo). 2005;53(8):934-7. PubMed PMID: 16079523.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Studies on the constituents of Juglans species. I. Structural determination of (4S)- and (4R)-4-hydroxy-alpha-tetralone derivatives from the fruit of Juglans mandshurica MAXIM. var. sieboldiana MAKINO. AU - Machida,Koichi, AU - Matsuoka,Erika, AU - Kasahara,Takayuki, AU - Kikuchi,Masao, PY - 2005/8/5/pubmed PY - 2005/10/15/medline PY - 2005/8/5/entrez SP - 934 EP - 7 JF - Chemical & pharmaceutical bulletin JO - Chem Pharm Bull (Tokyo) VL - 53 IS - 8 N2 - Four enantiomerically pure new alpha-tetralones, (4S)- and (4R)-5-hydroxy-4-methoxy-alpha-tetralones and (4S)- and (4R)-5,8-dihydroxy-4-methoxy-alpha-tetralones were isolated, together with five known ones, (4S)- and (4R)-4,8-dihydroxy-alpha-tetralones, (4S)-4,8-dihydroxy-5-methoxy-alpha-tetralone and (4S)- and (4R)-4-hydroxy-alpha-tetralones, from the fruit of Juglans mandshurica MAXIM. var. sieboldiana MAKINO. Their structures were established on the basis of spectral analysis. To the best of our knowledge, this is the first isolation of the (4R)-4-hydroxy-alpha-tetralone derivative from Juglans species. SN - 0009-2363 UR - https://www.unboundmedicine.com/medline/citation/16079523/Studies_on_the_constituents_of_Juglans_species__I__Structural_determination_of__4S___and__4R__4_hydroxy_alpha_tetralone_derivatives_from_the_fruit_of_Juglans_mandshurica_MAXIM__var__sieboldiana_MAKINO_ DB - PRIME DP - Unbound Medicine ER -