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Study of an outbreak of ciguatera fish poisoning in Hong Kong.
Toxicon. 2005 Oct; 46(5):563-71.T

Abstract

Ciguatera fish poisoning (CFP) has been a significant and increasing public health problem in Hong Kong since 1980s. With growing demand for imported live coral fishes, the number of people who suffered from this disease has also been increasing. An outbreak of CFP in 2004 was the second most prominent in record as compared with the most significant one that occurred in 1998. In 2004, out of a total of 823 reported food poisoning outbreaks involving 3159 persons, 65 incidents (7.9%) affecting 247 people (7.8%) were attributed to CFP. Validated mouse bioassay analysis of surveillance samples revealed that seven samples (13%) were confirmed to be contaminated with ciguatoxins (CTXs). Typical symptoms of CTXs were found in mice injected with 20mg of fish extracts. The causative fishes included Cheilinus undulatus, Epinephelus coioides, Plectropomus areolatus, and Plectropomus leopardus. Most of these CTX-positive samples analyzed had only trace amounts of CTXs in their extract, except a C. undulatus sample which contained a mice lethal dose (2.5MU/20mg ether extract). This fish species was also the major origin of coral fish that caused clusters of CFP in the last quarter of 2004. Cigua-Check analysis of 20 flesh grains from seven CTX-positive fishes, previously confirmed as CTX-positive samples by mouse bioassay, showed that 50% of flesh grains were CTX contaminated.

Authors+Show Affiliations

Biotoxin Laboratory, Public Health Laboratory Services Branch, Centre for Health Protection, Department of Health, Shek Kip Mei, Kowloon, Hong Kong.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16085209

Citation

Wong, Chun-Kwan, et al. "Study of an Outbreak of Ciguatera Fish Poisoning in Hong Kong." Toxicon : Official Journal of the International Society On Toxinology, vol. 46, no. 5, 2005, pp. 563-71.
Wong CK, Hung P, Lee KL, et al. Study of an outbreak of ciguatera fish poisoning in Hong Kong. Toxicon. 2005;46(5):563-71.
Wong, C. K., Hung, P., Lee, K. L., & Kam, K. M. (2005). Study of an outbreak of ciguatera fish poisoning in Hong Kong. Toxicon : Official Journal of the International Society On Toxinology, 46(5), 563-71.
Wong CK, et al. Study of an Outbreak of Ciguatera Fish Poisoning in Hong Kong. Toxicon. 2005;46(5):563-71. PubMed PMID: 16085209.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Study of an outbreak of ciguatera fish poisoning in Hong Kong. AU - Wong,Chun-Kwan, AU - Hung,Patricia, AU - Lee,Kellie L H, AU - Kam,Kai-Man, PY - 2005/05/05/received PY - 2005/06/22/revised PY - 2005/06/23/accepted PY - 2005/8/9/pubmed PY - 2006/2/8/medline PY - 2005/8/9/entrez SP - 563 EP - 71 JF - Toxicon : official journal of the International Society on Toxinology JO - Toxicon VL - 46 IS - 5 N2 - Ciguatera fish poisoning (CFP) has been a significant and increasing public health problem in Hong Kong since 1980s. With growing demand for imported live coral fishes, the number of people who suffered from this disease has also been increasing. An outbreak of CFP in 2004 was the second most prominent in record as compared with the most significant one that occurred in 1998. In 2004, out of a total of 823 reported food poisoning outbreaks involving 3159 persons, 65 incidents (7.9%) affecting 247 people (7.8%) were attributed to CFP. Validated mouse bioassay analysis of surveillance samples revealed that seven samples (13%) were confirmed to be contaminated with ciguatoxins (CTXs). Typical symptoms of CTXs were found in mice injected with 20mg of fish extracts. The causative fishes included Cheilinus undulatus, Epinephelus coioides, Plectropomus areolatus, and Plectropomus leopardus. Most of these CTX-positive samples analyzed had only trace amounts of CTXs in their extract, except a C. undulatus sample which contained a mice lethal dose (2.5MU/20mg ether extract). This fish species was also the major origin of coral fish that caused clusters of CFP in the last quarter of 2004. Cigua-Check analysis of 20 flesh grains from seven CTX-positive fishes, previously confirmed as CTX-positive samples by mouse bioassay, showed that 50% of flesh grains were CTX contaminated. SN - 0041-0101 UR - https://www.unboundmedicine.com/medline/citation/16085209/Study_of_an_outbreak_of_ciguatera_fish_poisoning_in_Hong_Kong_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0041-0101(05)00233-3 DB - PRIME DP - Unbound Medicine ER -