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In vitro evaluation of iron solubility and dialyzability of various iron fortificants and of iron-fortified milk products targeted for infants and toddlers.
Int J Food Sci Nutr. 2005 Jun; 56(4):293-302.IJ

Abstract

The objectives of the present study were: to compare the solubility and dialyzability of various iron fortificants (iron pyrophosphate, ferrous bis-glycinate, ferrous gluconate, ferrous lactate, ferrous sulfate) added, in the presence of ascorbic acid, to pasteurized milk samples produced under laboratory conditions; and to compare the solubility and dialyzability of iron in commercial pasteurized, UHT and condensed milk products available in the Greek market fortified with various vitamins and minerals including iron and targeted towards infants (6-12 months old) and toddlers. Iron solubility and dialyzability were determined using a simulated gastrointestinal digestive system. Ferrous dialyzable iron (molecular weight lower than 8000) was used as an index for prediction of iron bioavailability. Ferrous dialyzable iron in pasteurized milk samples fortified with iron pyrophosphate, ferrous lactate and ferrous bis-glycinate was higher (P < 0.05) than that in milk samples fortified with ferrous sulfate and ferrous gluconate. In commercial liquid pasteurized or UHT milk products, formation of ferrous dialyzable iron in products fortified with ferrous lactate was not different (P > 0.05) from those fortified with ferrous sulfate. Ferrous dialyzable iron in four condensed commercial milk products was higher (P < 0.05) than the corresponding values of the liquid UHT milk samples fortified with the same fortificant (ferrous sulfate). Ferrous dialyzable iron was higher (P < 0.05) in products targeted for infants compared with those targeted for toddlers. In conclusion, the type of iron source, milk processing and the overall product composition affect formation of ferrous dialyzable iron and may determine the success and effectiveness of iron fortification of milk.

Authors+Show Affiliations

Department of Food Science and Technology, Agricultural University of Athens, Iera Odos, Athens, Greece. kapsok@aua.grNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16096139

Citation

Kapsokefalou, Maria, et al. "In Vitro Evaluation of Iron Solubility and Dialyzability of Various Iron Fortificants and of Iron-fortified Milk Products Targeted for Infants and Toddlers." International Journal of Food Sciences and Nutrition, vol. 56, no. 4, 2005, pp. 293-302.
Kapsokefalou M, Alexandropoulou I, Komaitis M, et al. In vitro evaluation of iron solubility and dialyzability of various iron fortificants and of iron-fortified milk products targeted for infants and toddlers. Int J Food Sci Nutr. 2005;56(4):293-302.
Kapsokefalou, M., Alexandropoulou, I., Komaitis, M., & Politis, I. (2005). In vitro evaluation of iron solubility and dialyzability of various iron fortificants and of iron-fortified milk products targeted for infants and toddlers. International Journal of Food Sciences and Nutrition, 56(4), 293-302.
Kapsokefalou M, et al. In Vitro Evaluation of Iron Solubility and Dialyzability of Various Iron Fortificants and of Iron-fortified Milk Products Targeted for Infants and Toddlers. Int J Food Sci Nutr. 2005;56(4):293-302. PubMed PMID: 16096139.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - In vitro evaluation of iron solubility and dialyzability of various iron fortificants and of iron-fortified milk products targeted for infants and toddlers. AU - Kapsokefalou,Maria, AU - Alexandropoulou,Isidora, AU - Komaitis,Michail, AU - Politis,Ioannis, PY - 2005/8/13/pubmed PY - 2005/11/3/medline PY - 2005/8/13/entrez SP - 293 EP - 302 JF - International journal of food sciences and nutrition JO - Int J Food Sci Nutr VL - 56 IS - 4 N2 - The objectives of the present study were: to compare the solubility and dialyzability of various iron fortificants (iron pyrophosphate, ferrous bis-glycinate, ferrous gluconate, ferrous lactate, ferrous sulfate) added, in the presence of ascorbic acid, to pasteurized milk samples produced under laboratory conditions; and to compare the solubility and dialyzability of iron in commercial pasteurized, UHT and condensed milk products available in the Greek market fortified with various vitamins and minerals including iron and targeted towards infants (6-12 months old) and toddlers. Iron solubility and dialyzability were determined using a simulated gastrointestinal digestive system. Ferrous dialyzable iron (molecular weight lower than 8000) was used as an index for prediction of iron bioavailability. Ferrous dialyzable iron in pasteurized milk samples fortified with iron pyrophosphate, ferrous lactate and ferrous bis-glycinate was higher (P < 0.05) than that in milk samples fortified with ferrous sulfate and ferrous gluconate. In commercial liquid pasteurized or UHT milk products, formation of ferrous dialyzable iron in products fortified with ferrous lactate was not different (P > 0.05) from those fortified with ferrous sulfate. Ferrous dialyzable iron in four condensed commercial milk products was higher (P < 0.05) than the corresponding values of the liquid UHT milk samples fortified with the same fortificant (ferrous sulfate). Ferrous dialyzable iron was higher (P < 0.05) in products targeted for infants compared with those targeted for toddlers. In conclusion, the type of iron source, milk processing and the overall product composition affect formation of ferrous dialyzable iron and may determine the success and effectiveness of iron fortification of milk. SN - 0963-7486 UR - https://www.unboundmedicine.com/medline/citation/16096139/In_vitro_evaluation_of_iron_solubility_and_dialyzability_of_various_iron_fortificants_and_of_iron_fortified_milk_products_targeted_for_infants_and_toddlers_ DB - PRIME DP - Unbound Medicine ER -