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Treatment of localized persistent plaque psoriasis with incoherent narrowband ultraviolet B phototherapy.
J Dermatolog Treat. 2005 Aug; 16(3):165-8.JD

Abstract

PURPOSE

This study evaluated the efficacy of targeted UVB phototherapy treatment of chronic persistent psoratic plaques with localized incoherent UVB phototherapy.

METHODS

Sixteen subjects were enrolled. The final group was composed of eight men and seven women, each having one to seven chronic, stable psoriatic plaques. Each plaque was treated with fluences ranging from 3 to 7 MED using a fibre-coupled incoherent phototherapy device twice weekly for a maximum of 13 sessions. Assessments with a combination of three scores, each on a scale from 0 to 4, for scaling, erythema and induration (SEI score) were performed.

RESULTS

The patients received from 6 to 13 sessions (mean 9.6). The SEI score decreased by 3.3 (p = 0.01). This reduction was equally detected in all subscores. In a few patients, blistering and burning sensation after some sessions were noted.

CONCLUSION

Localized UVB phototherapy is an effective treatment option for persistent plaques of psoriasis. Compared with conventional UVB, localized phototherapy has the added safety benefit of virtually eliminating unwanted exposure of the healthy tissue to UVB.

Authors+Show Affiliations

Department of Dermatology, Hospital del Mar, IMAS, Barcelona, Spain. atoll@imas.imim.esNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16096183

Citation

Toll, Agustí, et al. "Treatment of Localized Persistent Plaque Psoriasis With Incoherent Narrowband Ultraviolet B Phototherapy." The Journal of Dermatological Treatment, vol. 16, no. 3, 2005, pp. 165-8.
Toll A, Vélez-González M, Gallardo F, et al. Treatment of localized persistent plaque psoriasis with incoherent narrowband ultraviolet B phototherapy. J Dermatolog Treat. 2005;16(3):165-8.
Toll, A., Vélez-González, M., Gallardo, F., Gilaberte, M., & Pujol, R. M. (2005). Treatment of localized persistent plaque psoriasis with incoherent narrowband ultraviolet B phototherapy. The Journal of Dermatological Treatment, 16(3), 165-8.
Toll A, et al. Treatment of Localized Persistent Plaque Psoriasis With Incoherent Narrowband Ultraviolet B Phototherapy. J Dermatolog Treat. 2005;16(3):165-8. PubMed PMID: 16096183.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment of localized persistent plaque psoriasis with incoherent narrowband ultraviolet B phototherapy. AU - Toll,Agustí, AU - Vélez-González,Mariano, AU - Gallardo,Fernando, AU - Gilaberte,Montserrat, AU - Pujol,Ramón M, PY - 2005/8/13/pubmed PY - 2006/1/4/medline PY - 2005/8/13/entrez SP - 165 EP - 8 JF - The Journal of dermatological treatment JO - J Dermatolog Treat VL - 16 IS - 3 N2 - PURPOSE: This study evaluated the efficacy of targeted UVB phototherapy treatment of chronic persistent psoratic plaques with localized incoherent UVB phototherapy. METHODS: Sixteen subjects were enrolled. The final group was composed of eight men and seven women, each having one to seven chronic, stable psoriatic plaques. Each plaque was treated with fluences ranging from 3 to 7 MED using a fibre-coupled incoherent phototherapy device twice weekly for a maximum of 13 sessions. Assessments with a combination of three scores, each on a scale from 0 to 4, for scaling, erythema and induration (SEI score) were performed. RESULTS: The patients received from 6 to 13 sessions (mean 9.6). The SEI score decreased by 3.3 (p = 0.01). This reduction was equally detected in all subscores. In a few patients, blistering and burning sensation after some sessions were noted. CONCLUSION: Localized UVB phototherapy is an effective treatment option for persistent plaques of psoriasis. Compared with conventional UVB, localized phototherapy has the added safety benefit of virtually eliminating unwanted exposure of the healthy tissue to UVB. SN - 0954-6634 UR - https://www.unboundmedicine.com/medline/citation/16096183/Treatment_of_localized_persistent_plaque_psoriasis_with_incoherent_narrowband_ultraviolet_B_phototherapy_ L2 - http://www.tandfonline.com/doi/full/10.1080/09546630510043211 DB - PRIME DP - Unbound Medicine ER -