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Onset of obsessive-compulsive disorder in pregnancy.
Am J Psychiatry 1992; 149(7):947-50AJ

Abstract

OBJECTIVE

Although the role of pregnancy and childbirth in postpartum psychosis and depression has been studied, the association between pregnancy and obsessive-compulsive disorder has not been specifically addressed. The authors evaluated the role of pregnancy in the onset of obsessive-compulsive disorder.

METHOD

Female patients with obsessive-compulsive disorder (N = 106) completed a questionnaire assessing age at onset of symptoms, marital status, number of children, age at each pregnancy, and life events associated with the onset of obsessive-compulsive disorder.

RESULTS

Of the 106 women, 42 were childless and 59 had at least one child each; five others were also childless but had had abortions (N = 4) or a miscarriage (N = 1). Of the 42 women without children, 12 (28.6%) had first experienced obsessive-compulsive symptoms between the ages of 13 and 15 years, but there were two peaks of onset for the women with children: ages 22-24 and 29-32 years. Of the 59 patients with children, 23 (39.0%) had experienced symptom onset during pregnancy; this was the first pregnancy for 12, the second pregnancy for eight, and the third pregnancy for three. Four of the five women who had had abortions or a miscarriage had experienced the onset or an exacerbation of obsessive-compulsive symptoms during pregnancy.

CONCLUSIONS

The association between pregnancy and the onset of obsessive-compulsive symptoms in these female patients highlights the need for further research on psychological and biological factors associated with pregnancy and obsessive-compulsive disorder.

Authors+Show Affiliations

Bio-Behavioral Psychiatry, Great Neck, NY 11021.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1609876

Citation

Neziroglu, F, et al. "Onset of Obsessive-compulsive Disorder in Pregnancy." The American Journal of Psychiatry, vol. 149, no. 7, 1992, pp. 947-50.
Neziroglu F, Anemone R, Yaryura-Tobias JA. Onset of obsessive-compulsive disorder in pregnancy. Am J Psychiatry. 1992;149(7):947-50.
Neziroglu, F., Anemone, R., & Yaryura-Tobias, J. A. (1992). Onset of obsessive-compulsive disorder in pregnancy. The American Journal of Psychiatry, 149(7), pp. 947-50.
Neziroglu F, Anemone R, Yaryura-Tobias JA. Onset of Obsessive-compulsive Disorder in Pregnancy. Am J Psychiatry. 1992;149(7):947-50. PubMed PMID: 1609876.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Onset of obsessive-compulsive disorder in pregnancy. AU - Neziroglu,F, AU - Anemone,R, AU - Yaryura-Tobias,J A, PY - 1992/7/1/pubmed PY - 1992/7/1/medline PY - 1992/7/1/entrez KW - Age Factors KW - Behavior KW - Data Collection KW - Demographic Factors KW - Diseases KW - Population KW - Population Characteristics KW - Postpartum Women KW - Pregnancy KW - Psychological Factors KW - Puerperium KW - Reproduction KW - Research Methodology KW - Signs And Symptoms KW - Stress SP - 947 EP - 50 JF - The American journal of psychiatry JO - Am J Psychiatry VL - 149 IS - 7 N2 - OBJECTIVE: Although the role of pregnancy and childbirth in postpartum psychosis and depression has been studied, the association between pregnancy and obsessive-compulsive disorder has not been specifically addressed. The authors evaluated the role of pregnancy in the onset of obsessive-compulsive disorder. METHOD: Female patients with obsessive-compulsive disorder (N = 106) completed a questionnaire assessing age at onset of symptoms, marital status, number of children, age at each pregnancy, and life events associated with the onset of obsessive-compulsive disorder. RESULTS: Of the 106 women, 42 were childless and 59 had at least one child each; five others were also childless but had had abortions (N = 4) or a miscarriage (N = 1). Of the 42 women without children, 12 (28.6%) had first experienced obsessive-compulsive symptoms between the ages of 13 and 15 years, but there were two peaks of onset for the women with children: ages 22-24 and 29-32 years. Of the 59 patients with children, 23 (39.0%) had experienced symptom onset during pregnancy; this was the first pregnancy for 12, the second pregnancy for eight, and the third pregnancy for three. Four of the five women who had had abortions or a miscarriage had experienced the onset or an exacerbation of obsessive-compulsive symptoms during pregnancy. CONCLUSIONS: The association between pregnancy and the onset of obsessive-compulsive symptoms in these female patients highlights the need for further research on psychological and biological factors associated with pregnancy and obsessive-compulsive disorder. SN - 0002-953X UR - https://www.unboundmedicine.com/medline/citation/1609876/Onset_of_obsessive_compulsive_disorder_in_pregnancy_ L2 - https://ajp.psychiatryonline.org/doi/full/10.1176/ajp.149.7.947?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -