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The evolving role of staging laparoscopy in the treatment of colorectal hepatic metastasis.
Arch Surg. 2005 Aug; 140(8):727-34.AS

Abstract

HYPOTHESIS

Laparoscopy is an increasingly important tool in the staging and treatment of hepatic malignancies. This study evaluates the effect of staging laparoscopy (SL) using intraoperative ultrasonography (IOUS) on the regional treatment of isolated hepatic colorectal metastasis.

DESIGN

Analytic cohort study.

SETTING

Tertiary care center.

PATIENTS

Consecutive patients who have a colorectal metastasis confined to the liver and selected for surgical regional treatment.

INTERVENTIONS

All patients underwent preoperative evaluation followed by SL/IOUS. Operative plans were based on preoperative imaging and were either carried out or altered intraoperatively according to SL/IOUS findings.

MAIN OUTCOME MEASURE

Effect of SL/IOUS on surgical management.

RESULTS

Between September 1996 and May 2004 one hundred fifty-two SL/IOUSs were performed in 136 patients (77 males and 59 females), who had a mean (SD) age of 63 (11) years. Data sets were complete in 138 events. All patients had isolated hepatic disease as defined by preoperative computed tomography in 152 (100%) and positron emission tomography in 107 (70%). Staging laparoscopy/IOUS identified surgically untreatable disease in 34 events (25%) because of peritoneal metastases (n = 15), nodal involvement (n = 11), diffuse hepatic disease (n = 5), no identifiable disease (n = 2), and untreatable disease (n = 1). Laparoscopic treatment events included radiofrequency ablations (n = 78), hepatic artery pump implantations (n = 40), resections (n = 26), and combined procedures (n = 37). Overall, SL/IOUS changed the treatment plan in 66 (48%) of 138 of events. This includes 32 (23%) of 138 events in which SL/IOUS findings significantly altered the actual procedure performed relative to the preoperative plan. Three minor complications occurred in the SL/IOUS-only group with a mean (SD) hospital stay of 1.3 (1) days.

CONCLUSION

In the regional management of isolated colorectal hepatic metastasis, SL/IOUS avoids unnecessary laparotomies and influences definitive surgical intervention in a substantial proportion of patients.

Authors+Show Affiliations

Department of Hepatobiliary and Pancreatic Surgery, Legacy Health System, 1040 NW 22nd Avenue, Portland, OR 97210, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16103281

Citation

Thaler, Klaus, et al. "The Evolving Role of Staging Laparoscopy in the Treatment of Colorectal Hepatic Metastasis." Archives of Surgery (Chicago, Ill. : 1960), vol. 140, no. 8, 2005, pp. 727-34.
Thaler K, Kanneganti S, Khajanchee Y, et al. The evolving role of staging laparoscopy in the treatment of colorectal hepatic metastasis. Arch Surg. 2005;140(8):727-34.
Thaler, K., Kanneganti, S., Khajanchee, Y., Wilson, C., Swanstrom, L., & Hansen, P. D. (2005). The evolving role of staging laparoscopy in the treatment of colorectal hepatic metastasis. Archives of Surgery (Chicago, Ill. : 1960), 140(8), 727-34.
Thaler K, et al. The Evolving Role of Staging Laparoscopy in the Treatment of Colorectal Hepatic Metastasis. Arch Surg. 2005;140(8):727-34. PubMed PMID: 16103281.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The evolving role of staging laparoscopy in the treatment of colorectal hepatic metastasis. AU - Thaler,Klaus, AU - Kanneganti,Shalini, AU - Khajanchee,Yashohdan, AU - Wilson,Charlyn, AU - Swanstrom,Lee, AU - Hansen,Paul D, PY - 2005/8/17/pubmed PY - 2005/9/2/medline PY - 2005/8/17/entrez SP - 727 EP - 34 JF - Archives of surgery (Chicago, Ill. : 1960) JO - Arch Surg VL - 140 IS - 8 N2 - HYPOTHESIS: Laparoscopy is an increasingly important tool in the staging and treatment of hepatic malignancies. This study evaluates the effect of staging laparoscopy (SL) using intraoperative ultrasonography (IOUS) on the regional treatment of isolated hepatic colorectal metastasis. DESIGN: Analytic cohort study. SETTING: Tertiary care center. PATIENTS: Consecutive patients who have a colorectal metastasis confined to the liver and selected for surgical regional treatment. INTERVENTIONS: All patients underwent preoperative evaluation followed by SL/IOUS. Operative plans were based on preoperative imaging and were either carried out or altered intraoperatively according to SL/IOUS findings. MAIN OUTCOME MEASURE: Effect of SL/IOUS on surgical management. RESULTS: Between September 1996 and May 2004 one hundred fifty-two SL/IOUSs were performed in 136 patients (77 males and 59 females), who had a mean (SD) age of 63 (11) years. Data sets were complete in 138 events. All patients had isolated hepatic disease as defined by preoperative computed tomography in 152 (100%) and positron emission tomography in 107 (70%). Staging laparoscopy/IOUS identified surgically untreatable disease in 34 events (25%) because of peritoneal metastases (n = 15), nodal involvement (n = 11), diffuse hepatic disease (n = 5), no identifiable disease (n = 2), and untreatable disease (n = 1). Laparoscopic treatment events included radiofrequency ablations (n = 78), hepatic artery pump implantations (n = 40), resections (n = 26), and combined procedures (n = 37). Overall, SL/IOUS changed the treatment plan in 66 (48%) of 138 of events. This includes 32 (23%) of 138 events in which SL/IOUS findings significantly altered the actual procedure performed relative to the preoperative plan. Three minor complications occurred in the SL/IOUS-only group with a mean (SD) hospital stay of 1.3 (1) days. CONCLUSION: In the regional management of isolated colorectal hepatic metastasis, SL/IOUS avoids unnecessary laparotomies and influences definitive surgical intervention in a substantial proportion of patients. SN - 0004-0010 UR - https://www.unboundmedicine.com/medline/citation/16103281/The_evolving_role_of_staging_laparoscopy_in_the_treatment_of_colorectal_hepatic_metastasis_ L2 - https://jamanetwork.com/journals/jamasurgery/fullarticle/10.1001/archsurg.140.8.727 DB - PRIME DP - Unbound Medicine ER -