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Antimicrobial activities of Barringtonia acutangula.
Phytother Res. 2005 Jun; 19(6):543-5.PR

Abstract

Crude extracts and VLC fractions from the stem bark of Barringtonia acutangula (L.) Gaertn (Fam. Lecythidaceae) were screened for their antimicrobial activities against two Gram-positive bacteria, two Gram-negative bacteria and two fungi using a microdilution titre assay. Among the crude extracts, petroleum ether extract showed good activity against all test organisms. The VLC fraction PE 16 was found to be very effective against Bacillus subtilis (MIC=25 microg/ml) and Aspergillus niger (MIC=12.5 microg/ml). The activities were compared to standard antibiotics-kanamycin and fluconazole. The major compound from PE16 was identified as 12, 20(29)-lupadien-3-ol by NMR spectroscopy.

Authors+Show Affiliations

Rahman MM
Phytochemistry Research Laboratories, Department of Pharmaceutical Sciences, University of Strathclyde, Glasgow, UK.
Polfreman D
No affiliation info available
MacGeachan J
No affiliation info available
Gray AI
No affiliation info available

MeSH

Anti-Bacterial AgentsAntifungal AgentsAspergillus nigerBacillus subtilisBarringtoniaGram-Negative BacteriaGram-Positive BacteriaHumansMicrobial Sensitivity TestsPhytotherapyPlant BarkPlant Extracts

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16114086

Citation

Rahman, M Mukhlesur, et al. "Antimicrobial Activities of Barringtonia Acutangula." Phytotherapy Research : PTR, vol. 19, no. 6, 2005, pp. 543-5.
Rahman MM, Polfreman D, MacGeachan J, et al. Antimicrobial activities of Barringtonia acutangula. Phytother Res. 2005;19(6):543-5.
Rahman, M. M., Polfreman, D., MacGeachan, J., & Gray, A. I. (2005). Antimicrobial activities of Barringtonia acutangula. Phytotherapy Research : PTR, 19(6), 543-5.
Rahman MM, et al. Antimicrobial Activities of Barringtonia Acutangula. Phytother Res. 2005;19(6):543-5. PubMed PMID: 16114086.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial activities of Barringtonia acutangula. AU - Rahman,M Mukhlesur, AU - Polfreman,David, AU - MacGeachan,Jodie, AU - Gray,Alexander I, PY - 2005/8/23/pubmed PY - 2005/10/21/medline PY - 2005/8/23/entrez SP - 543 EP - 5 JF - Phytotherapy research : PTR JO - Phytother Res VL - 19 IS - 6 N2 - Crude extracts and VLC fractions from the stem bark of Barringtonia acutangula (L.) Gaertn (Fam. Lecythidaceae) were screened for their antimicrobial activities against two Gram-positive bacteria, two Gram-negative bacteria and two fungi using a microdilution titre assay. Among the crude extracts, petroleum ether extract showed good activity against all test organisms. The VLC fraction PE 16 was found to be very effective against Bacillus subtilis (MIC=25 microg/ml) and Aspergillus niger (MIC=12.5 microg/ml). The activities were compared to standard antibiotics-kanamycin and fluconazole. The major compound from PE16 was identified as 12, 20(29)-lupadien-3-ol by NMR spectroscopy. SN - 0951-418X UR - https://www.unboundmedicine.com/medline/citation/16114086/Antimicrobial_activities_of_Barringtonia_acutangula_ DB - PRIME DP - Unbound Medicine ER -