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[The polypill: not an effective strategy for reduction of cardiovascular disease].
Ned Tijdschr Geneeskd. 2005 Jul 30; 149(31):1741.NT

Abstract

The implementation of the intriguing concept of the polypill to prevent cardiovascular events remains doubtful due to a lack of evidence, expected adherence problems, the inevitable overtreatment and undertreatment of individuals, and potential side effects. Lifestyle changes and individual interventions are more preferable strategies.

Authors+Show Affiliations

Westerweel PE
Universitair Medisch Centrum Utrecht, afd. Vasculaire Geneeskunde, Heidelberglaan 100, 3584 CX Utrecht.
van Wijk JP
No affiliation info available
Verhaar MC
No affiliation info available

MeSH

Antihypertensive AgentsAspirinCardiovascular DiseasesDrug CombinationsEvidence-Based MedicineFemaleFolic AcidHumansHydroxymethylglutaryl-CoA Reductase InhibitorsLife StyleMaleMiddle AgedPatient CompliancePlatelet Aggregation InhibitorsPrimary Prevention

Pub Type(s)

Comment
English Abstract
Journal Article

Language

dut

PubMed ID

16114291

Citation

Westerweel, P E., et al. "[The Polypill: Not an Effective Strategy for Reduction of Cardiovascular Disease]." Nederlands Tijdschrift Voor Geneeskunde, vol. 149, no. 31, 2005, p. 1741.
Westerweel PE, van Wijk JP, Verhaar MC. [The polypill: not an effective strategy for reduction of cardiovascular disease]. Ned Tijdschr Geneeskd. 2005;149(31):1741.
Westerweel, P. E., van Wijk, J. P., & Verhaar, M. C. (2005). [The polypill: not an effective strategy for reduction of cardiovascular disease]. Nederlands Tijdschrift Voor Geneeskunde, 149(31), 1741.
Westerweel PE, van Wijk JP, Verhaar MC. [The Polypill: Not an Effective Strategy for Reduction of Cardiovascular Disease]. Ned Tijdschr Geneeskd. 2005 Jul 30;149(31):1741. PubMed PMID: 16114291.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The polypill: not an effective strategy for reduction of cardiovascular disease]. AU - Westerweel,P E, AU - van Wijk,J P H, AU - Verhaar,M C, PY - 2005/8/24/pubmed PY - 2005/9/24/medline PY - 2005/8/24/entrez SP - 1741 EP - 1741 JF - Nederlands tijdschrift voor geneeskunde JO - Ned Tijdschr Geneeskd VL - 149 IS - 31 N2 - The implementation of the intriguing concept of the polypill to prevent cardiovascular events remains doubtful due to a lack of evidence, expected adherence problems, the inevitable overtreatment and undertreatment of individuals, and potential side effects. Lifestyle changes and individual interventions are more preferable strategies. SN - 0028-2162 UR - https://www.unboundmedicine.com/medline/citation/16114291/[The_polypill:_not_an_effective_strategy_for_reduction_of_cardiovascular_disease]_ DB - PRIME DP - Unbound Medicine ER -