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Essential trace elements selenium, zinc, copper, and iron concentrations and their related acute-phase proteins in patients with vivax malaria.
Biol Trace Elem Res 2005; 106(2):107-15BT

Abstract

The aim of the present study is to evaluate the status of plasma essential trace elements selenium (Se), zinc (Zn), copper (Cu), and iron (Fe) concentrations and their related acute-phase proteins, ceruloplasmin (Cp), ferritin, transferrin (Tf), and albumin levels in patients with vivax malaria. Plasma Cu and Zn concentrations were determined by atomic absorption spectrometry (AAS). Se concentrations were determined by graphite furnace AAS. Fe, Cp, Tf, and albumin levels were determined by colorimetric methods. Plasma Se, Fe, and albumin levels were found to be significantly lower (p < 0.01, p < 0.001, and p < 0.05, respectively) and Cu, Cp, and ferritin levels and Cu/Zn ratios were significantly higher (p < 0.001, p < 0.001, p < 0.001, and p < 0.05, respectively) in patients when compared with those of healthy subjects. Plasma, Tf, and Zn levels were not found to be significantly different (p > 0.05) in patients and controls. There were positive important correlations between Cu and Cp (r = 0.908, p < 0.001), Zn and albumin (r = 0.633, p < 0.001), and negative correlations between Fe and ferritin content (r = -0.521, p < 0.05) and Fe and Tf (r = -0.616, p < 0.01) in the patients group. Our findings demonstrated that plasma essential trace elements Se, Cu, and Fe change, but these changes might be dependent on acute-phase proteins, which were regulated as a part of defense strategies of the organism, induced by hormonelike substances.

Authors+Show Affiliations

Department of Microbiology, Medical Faculty, Firat University, Elazig, Turkey.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16116242

Citation

Seyrek, Adnan, et al. "Essential Trace Elements Selenium, Zinc, Copper, and Iron Concentrations and Their Related Acute-phase Proteins in Patients With Vivax Malaria." Biological Trace Element Research, vol. 106, no. 2, 2005, pp. 107-15.
Seyrek A, Kocyigit A, Erel O. Essential trace elements selenium, zinc, copper, and iron concentrations and their related acute-phase proteins in patients with vivax malaria. Biol Trace Elem Res. 2005;106(2):107-15.
Seyrek, A., Kocyigit, A., & Erel, O. (2005). Essential trace elements selenium, zinc, copper, and iron concentrations and their related acute-phase proteins in patients with vivax malaria. Biological Trace Element Research, 106(2), pp. 107-15.
Seyrek A, Kocyigit A, Erel O. Essential Trace Elements Selenium, Zinc, Copper, and Iron Concentrations and Their Related Acute-phase Proteins in Patients With Vivax Malaria. Biol Trace Elem Res. 2005;106(2):107-15. PubMed PMID: 16116242.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Essential trace elements selenium, zinc, copper, and iron concentrations and their related acute-phase proteins in patients with vivax malaria. AU - Seyrek,Adnan, AU - Kocyigit,Abdurrahim, AU - Erel,Ozcan, PY - 2004/08/24/received PY - 2004/10/11/revised PY - 2004/10/29/accepted PY - 2005/8/24/pubmed PY - 2005/11/5/medline PY - 2005/8/24/entrez SP - 107 EP - 15 JF - Biological trace element research JO - Biol Trace Elem Res VL - 106 IS - 2 N2 - The aim of the present study is to evaluate the status of plasma essential trace elements selenium (Se), zinc (Zn), copper (Cu), and iron (Fe) concentrations and their related acute-phase proteins, ceruloplasmin (Cp), ferritin, transferrin (Tf), and albumin levels in patients with vivax malaria. Plasma Cu and Zn concentrations were determined by atomic absorption spectrometry (AAS). Se concentrations were determined by graphite furnace AAS. Fe, Cp, Tf, and albumin levels were determined by colorimetric methods. Plasma Se, Fe, and albumin levels were found to be significantly lower (p < 0.01, p < 0.001, and p < 0.05, respectively) and Cu, Cp, and ferritin levels and Cu/Zn ratios were significantly higher (p < 0.001, p < 0.001, p < 0.001, and p < 0.05, respectively) in patients when compared with those of healthy subjects. Plasma, Tf, and Zn levels were not found to be significantly different (p > 0.05) in patients and controls. There were positive important correlations between Cu and Cp (r = 0.908, p < 0.001), Zn and albumin (r = 0.633, p < 0.001), and negative correlations between Fe and ferritin content (r = -0.521, p < 0.05) and Fe and Tf (r = -0.616, p < 0.01) in the patients group. Our findings demonstrated that plasma essential trace elements Se, Cu, and Fe change, but these changes might be dependent on acute-phase proteins, which were regulated as a part of defense strategies of the organism, induced by hormonelike substances. SN - 0163-4984 UR - https://www.unboundmedicine.com/medline/citation/16116242/Essential_trace_elements_selenium_zinc_copper_and_iron_concentrations_and_their_related_acute_phase_proteins_in_patients_with_vivax_malaria_ L2 - https://dx.doi.org/10.1385/BTER:106:2:107 DB - PRIME DP - Unbound Medicine ER -