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Vaccines for lyssaviruses other than rabies.
Expert Rev Vaccines. 2005 Aug; 4(4):533-40.ER

Abstract

Several new lyssaviruses have emerged in the past decade and it is likely that more remain to be discovered. There are six recognized genotypes of lyssavirus other than the rabies virus (genotype 1). All but one of these has been associated with human cases, with the resulting disease clinically similar to rabies. Rabies vaccines provide a means of pre- and postexposure prophylaxis against rabies and some of the other genotypes, but not all. Those that are crossprotected fall into phylogroup 1 of the genus, and those not protected in phylogroup 2. The crossprotection of phylogroup 1 viruses by rabies vaccines and the development of new, broader range or specific vaccines for phylogroup 2 viruses are reviewed.

Authors+Show Affiliations

Department of Microbiology, Faculty of Natural and Agricultutal Sciences, University of Pretoria, 0002 Pretoria, South Africa. louis.nel@up.ac.za

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16117710

Citation

Nel, Louis H.. "Vaccines for Lyssaviruses Other Than Rabies." Expert Review of Vaccines, vol. 4, no. 4, 2005, pp. 533-40.
Nel LH. Vaccines for lyssaviruses other than rabies. Expert Rev Vaccines. 2005;4(4):533-40.
Nel, L. H. (2005). Vaccines for lyssaviruses other than rabies. Expert Review of Vaccines, 4(4), 533-40.
Nel LH. Vaccines for Lyssaviruses Other Than Rabies. Expert Rev Vaccines. 2005;4(4):533-40. PubMed PMID: 16117710.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vaccines for lyssaviruses other than rabies. A1 - Nel,Louis H, PY - 2005/8/25/pubmed PY - 2006/6/7/medline PY - 2005/8/25/entrez SP - 533 EP - 40 JF - Expert review of vaccines JO - Expert Rev Vaccines VL - 4 IS - 4 N2 - Several new lyssaviruses have emerged in the past decade and it is likely that more remain to be discovered. There are six recognized genotypes of lyssavirus other than the rabies virus (genotype 1). All but one of these has been associated with human cases, with the resulting disease clinically similar to rabies. Rabies vaccines provide a means of pre- and postexposure prophylaxis against rabies and some of the other genotypes, but not all. Those that are crossprotected fall into phylogroup 1 of the genus, and those not protected in phylogroup 2. The crossprotection of phylogroup 1 viruses by rabies vaccines and the development of new, broader range or specific vaccines for phylogroup 2 viruses are reviewed. SN - 1744-8395 UR - https://www.unboundmedicine.com/medline/citation/16117710/Vaccines_for_lyssaviruses_other_than_rabies_ L2 - https://www.tandfonline.com/doi/full/10.1586/14760584.4.4.533 DB - PRIME DP - Unbound Medicine ER -