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Beneficial effect of a low glycaemic index diet in type 2 diabetes.
Diabet Med 1992; 9(5):451-8DM

Abstract

Low glycaemic index foods produce low blood glucose and insulin responses in normal subjects, and improve blood glucose control in Type 1 and well-controlled Type 2 diabetic patients. We studied the effects of a low glycaemic index diet in 15 Type 2 diabetic patients with a mean fasting blood glucose of 9.5 mmol l-1 using a randomized, crossover design. Patients were given pre-weighed diets (59% energy as carbohydrate, 21% fat, and 24 g 1000-kcal-1 dietary fibre) for two 2-week periods, with a diet glycaemic index of 60 during one period and 87 during the other. On the low glycaemic index diet, the blood glucose response after a representative breakfast was 29% less than on the high glycaemic index diet (874 +/- 108 (+/- SE) vs 204 +/- 112 mmol min l-1; p less than 0.001), the percentage reduction being almost identical to the 28% difference predicted from the meal glycaemic index values. After the 2-week low glycaemic index diet, fasting serum fructosamine and cholesterol levels were significantly less than after the high glycaemic index diet (3.17 +/- 0.12 vs 3.28 +/- 0.16 mmol l-1, p less than 0.05, and 5.5 +/- 0.4 vs 5.9 +/- 0.5 mmol l-1, p less than 0.02, respectively.(

ABSTRACT

TRUNCATED AT 250 WORDS)

Authors+Show Affiliations

Department of Nutritional Sciences, Faculty of Medicine, St Michael's Hospital, University of Toronto, Ontario, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1611833

Citation

Wolever, T M., et al. "Beneficial Effect of a Low Glycaemic Index Diet in Type 2 Diabetes." Diabetic Medicine : a Journal of the British Diabetic Association, vol. 9, no. 5, 1992, pp. 451-8.
Wolever TM, Jenkins DJ, Vuksan V, et al. Beneficial effect of a low glycaemic index diet in type 2 diabetes. Diabet Med. 1992;9(5):451-8.
Wolever, T. M., Jenkins, D. J., Vuksan, V., Jenkins, A. L., Buckley, G. C., Wong, G. S., & Josse, R. G. (1992). Beneficial effect of a low glycaemic index diet in type 2 diabetes. Diabetic Medicine : a Journal of the British Diabetic Association, 9(5), pp. 451-8.
Wolever TM, et al. Beneficial Effect of a Low Glycaemic Index Diet in Type 2 Diabetes. Diabet Med. 1992;9(5):451-8. PubMed PMID: 1611833.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Beneficial effect of a low glycaemic index diet in type 2 diabetes. AU - Wolever,T M, AU - Jenkins,D J, AU - Vuksan,V, AU - Jenkins,A L, AU - Buckley,G C, AU - Wong,G S, AU - Josse,R G, PY - 1992/6/1/pubmed PY - 1992/6/1/medline PY - 1992/6/1/entrez SP - 451 EP - 8 JF - Diabetic medicine : a journal of the British Diabetic Association JO - Diabet. Med. VL - 9 IS - 5 N2 - Low glycaemic index foods produce low blood glucose and insulin responses in normal subjects, and improve blood glucose control in Type 1 and well-controlled Type 2 diabetic patients. We studied the effects of a low glycaemic index diet in 15 Type 2 diabetic patients with a mean fasting blood glucose of 9.5 mmol l-1 using a randomized, crossover design. Patients were given pre-weighed diets (59% energy as carbohydrate, 21% fat, and 24 g 1000-kcal-1 dietary fibre) for two 2-week periods, with a diet glycaemic index of 60 during one period and 87 during the other. On the low glycaemic index diet, the blood glucose response after a representative breakfast was 29% less than on the high glycaemic index diet (874 +/- 108 (+/- SE) vs 204 +/- 112 mmol min l-1; p less than 0.001), the percentage reduction being almost identical to the 28% difference predicted from the meal glycaemic index values. After the 2-week low glycaemic index diet, fasting serum fructosamine and cholesterol levels were significantly less than after the high glycaemic index diet (3.17 +/- 0.12 vs 3.28 +/- 0.16 mmol l-1, p less than 0.05, and 5.5 +/- 0.4 vs 5.9 +/- 0.5 mmol l-1, p less than 0.02, respectively.(ABSTRACT TRUNCATED AT 250 WORDS) SN - 0742-3071 UR - https://www.unboundmedicine.com/medline/citation/1611833/Beneficial_effect_of_a_low_glycaemic_index_diet_in_type_2_diabetes_ L2 - http://www.diseaseinfosearch.org/result/2243 DB - PRIME DP - Unbound Medicine ER -