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[Efficacy of specific immunotherapy in the treatment of children and youngsters suffering from atopic dermatitis Part II. Evaluation of skin reactivity and concentration of serum antigen specific immunoglobulin E directed against selected airborne allergens].
Wiad Lek. 2005; 58(3-4):184-92.WL

Abstract

Atopic dermatitis (AD) still remains a difficult clinical problem in terms of effective therapy. The aim of our study was to evaluate efficacy of specific immunotherapy performed with Novo-Helisen Depot allergy vaccines in the group of 36 children and youngsters with atopic dermatitis allergic to house dust mites (24 persons) and grass pollen allergens (12 patients), for the time period of 3 years. Skin reactivity (skin prick tests) and serum concentrations of antigen specific IgE were monitored in the course of treatment. The control group consisted of 20 patients with atopic dermatitis and IgE-mediated airborne allergy who were treated with conventional methods. Specific immunotherapy resulted in negativization of skin prick tests results and decrease of serum antigen specific IgE concentrations. On the contrary in the control group there was no tendency for negativization of skin prick tests and we observed an increase of serum concentration of antigen specific IgE directed against grass pollen allergens. Specific immunotherapy seems to be an effective therapeutic approach in selected cases of atopic dermatitis.

Authors+Show Affiliations

Z Katedry i Kliniki Dermatologii, Akademii Medycznej w Poznaniu. wsilny@amp.edu.plNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

pol

PubMed ID

16119162

Citation

Silny, Wojciech, et al. "[Efficacy of Specific Immunotherapy in the Treatment of Children and Youngsters Suffering From Atopic Dermatitis Part II. Evaluation of Skin Reactivity and Concentration of Serum Antigen Specific Immunoglobulin E Directed Against Selected Airborne Allergens]." Wiadomosci Lekarskie (Warsaw, Poland : 1960), vol. 58, no. 3-4, 2005, pp. 184-92.
Silny W, Czarnecka-Operacz M, Silny P. [Efficacy of specific immunotherapy in the treatment of children and youngsters suffering from atopic dermatitis Part II. Evaluation of skin reactivity and concentration of serum antigen specific immunoglobulin E directed against selected airborne allergens]. Wiad Lek. 2005;58(3-4):184-92.
Silny, W., Czarnecka-Operacz, M., & Silny, P. (2005). [Efficacy of specific immunotherapy in the treatment of children and youngsters suffering from atopic dermatitis Part II. Evaluation of skin reactivity and concentration of serum antigen specific immunoglobulin E directed against selected airborne allergens]. Wiadomosci Lekarskie (Warsaw, Poland : 1960), 58(3-4), 184-92.
Silny W, Czarnecka-Operacz M, Silny P. [Efficacy of Specific Immunotherapy in the Treatment of Children and Youngsters Suffering From Atopic Dermatitis Part II. Evaluation of Skin Reactivity and Concentration of Serum Antigen Specific Immunoglobulin E Directed Against Selected Airborne Allergens]. Wiad Lek. 2005;58(3-4):184-92. PubMed PMID: 16119162.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Efficacy of specific immunotherapy in the treatment of children and youngsters suffering from atopic dermatitis Part II. Evaluation of skin reactivity and concentration of serum antigen specific immunoglobulin E directed against selected airborne allergens]. AU - Silny,Wojciech, AU - Czarnecka-Operacz,Magdalena, AU - Silny,Paweł, PY - 2005/8/27/pubmed PY - 2005/10/7/medline PY - 2005/8/27/entrez SP - 184 EP - 92 JF - Wiadomosci lekarskie (Warsaw, Poland : 1960) JO - Wiad Lek VL - 58 IS - 3-4 N2 - Atopic dermatitis (AD) still remains a difficult clinical problem in terms of effective therapy. The aim of our study was to evaluate efficacy of specific immunotherapy performed with Novo-Helisen Depot allergy vaccines in the group of 36 children and youngsters with atopic dermatitis allergic to house dust mites (24 persons) and grass pollen allergens (12 patients), for the time period of 3 years. Skin reactivity (skin prick tests) and serum concentrations of antigen specific IgE were monitored in the course of treatment. The control group consisted of 20 patients with atopic dermatitis and IgE-mediated airborne allergy who were treated with conventional methods. Specific immunotherapy resulted in negativization of skin prick tests results and decrease of serum antigen specific IgE concentrations. On the contrary in the control group there was no tendency for negativization of skin prick tests and we observed an increase of serum concentration of antigen specific IgE directed against grass pollen allergens. Specific immunotherapy seems to be an effective therapeutic approach in selected cases of atopic dermatitis. SN - 0043-5147 UR - https://www.unboundmedicine.com/medline/citation/16119162/[Efficacy_of_specific_immunotherapy_in_the_treatment_of_children_and_youngsters_suffering_from_atopic_dermatitis_Part_II__Evaluation_of_skin_reactivity_and_concentration_of_serum_antigen_specific_immunoglobulin_E_directed_against_selected_airborne_allergens]_ DB - PRIME DP - Unbound Medicine ER -