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Kidney crisis in systemic sclerosis.
Rocz Akad Med Bialymst. 2005; 50 Suppl 1:294-6.RA

Abstract

Renal crisis in systemic sclerosis occurs in the group of patients with rapid and aggressive course of the disease, often after several years of the ailment and with the diffuse form. Scleroderma renal crisis (SRC) is most frequently characterized by malignant hypertension, renal insufficiency, and less often by the symptoms of microangiopathic hemolytic anemia. Renal crisis symptoms appear suddenly and are not usually preceded by significant prodromal symptoms. SRC is always life-threatening and requires specific treatment with drugs blocking angiotensin-converting enzyme. Early diagnosis and introducing appropriate treatment give a patient a chance to survive SRC episode and improve his prognosis. SRC is of great importance to clinicians as it still causes high mortality rate. Chronic and subacute renal crisis is connected with a small risk of acute renal failure. However, it gradually leads to a substantial dysfunction of this organ. Thus, a useful examination in the diagnostics of chronic renal crisis is checking the vascular flow in renal cortex and evaluating intrarenal resistance.

Authors+Show Affiliations

Department of Rheumatology and Internal Diseases, Medical University in Białystok, Poland.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16119690

Citation

Lewandowski, B, et al. "Kidney Crisis in Systemic Sclerosis." Roczniki Akademii Medycznej W Bialymstoku (1995), vol. 50 Suppl 1, 2005, pp. 294-6.
Lewandowski B, Domysławska I, Klimiuk PA, et al. Kidney crisis in systemic sclerosis. Rocz Akad Med Bialymst. 2005;50 Suppl 1:294-6.
Lewandowski, B., Domysławska, I., Klimiuk, P. A., & Sierakowski, S. (2005). Kidney crisis in systemic sclerosis. Roczniki Akademii Medycznej W Bialymstoku (1995), 50 Suppl 1, 294-6.
Lewandowski B, et al. Kidney Crisis in Systemic Sclerosis. Rocz Akad Med Bialymst. 2005;50 Suppl 1:294-6. PubMed PMID: 16119690.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Kidney crisis in systemic sclerosis. AU - Lewandowski,B, AU - Domysławska,I, AU - Klimiuk,P A, AU - Sierakowski,S, PY - 2005/8/27/pubmed PY - 2005/10/12/medline PY - 2005/8/27/entrez SP - 294 EP - 6 JF - Roczniki Akademii Medycznej w Bialymstoku (1995) JO - Rocz. Akad. Med. Bialymst. VL - 50 Suppl 1 N2 - Renal crisis in systemic sclerosis occurs in the group of patients with rapid and aggressive course of the disease, often after several years of the ailment and with the diffuse form. Scleroderma renal crisis (SRC) is most frequently characterized by malignant hypertension, renal insufficiency, and less often by the symptoms of microangiopathic hemolytic anemia. Renal crisis symptoms appear suddenly and are not usually preceded by significant prodromal symptoms. SRC is always life-threatening and requires specific treatment with drugs blocking angiotensin-converting enzyme. Early diagnosis and introducing appropriate treatment give a patient a chance to survive SRC episode and improve his prognosis. SRC is of great importance to clinicians as it still causes high mortality rate. Chronic and subacute renal crisis is connected with a small risk of acute renal failure. However, it gradually leads to a substantial dysfunction of this organ. Thus, a useful examination in the diagnostics of chronic renal crisis is checking the vascular flow in renal cortex and evaluating intrarenal resistance. UR - https://www.unboundmedicine.com/medline/citation/16119690/Kidney_crisis_in_systemic_sclerosis_ L2 - http://www.diseaseinfosearch.org/result/2275 DB - PRIME DP - Unbound Medicine ER -