Efficient pd-catalyzed amination of heteroaryl halides.Org Lett. 2005 Sep 01; 7(18):3965-8.OL
Abstract
The Pd-catalyzed amination of a variety of heteroaryl halides has been accomplished by utilizing bulky electron-rich biaryl phosphine ligands. In particular, we report the first couplings of amines with chloro- and bromoindoles bearing a free NH, as well as the first Pd-catalyzed aminations of a 5-halopyrimidine. [reaction: see text]
MeSH
Pub Type(s)
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Language
eng
PubMed ID
16119943
Citation
Charles, Mark D., et al. "Efficient Pd-catalyzed Amination of Heteroaryl Halides." Organic Letters, vol. 7, no. 18, 2005, pp. 3965-8.
Charles MD, Schultz P, Buchwald SL. Efficient pd-catalyzed amination of heteroaryl halides. Org Lett. 2005;7(18):3965-8.
Charles, M. D., Schultz, P., & Buchwald, S. L. (2005). Efficient pd-catalyzed amination of heteroaryl halides. Organic Letters, 7(18), 3965-8.
Charles MD, Schultz P, Buchwald SL. Efficient Pd-catalyzed Amination of Heteroaryl Halides. Org Lett. 2005 Sep 1;7(18):3965-8. PubMed PMID: 16119943.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Efficient pd-catalyzed amination of heteroaryl halides.
AU - Charles,Mark D,
AU - Schultz,Phillip,
AU - Buchwald,Stephen L,
PY - 2005/8/27/pubmed
PY - 2006/7/21/medline
PY - 2005/8/27/entrez
SP - 3965
EP - 8
JF - Organic letters
JO - Org Lett
VL - 7
IS - 18
N2 - The Pd-catalyzed amination of a variety of heteroaryl halides has been accomplished by utilizing bulky electron-rich biaryl phosphine ligands. In particular, we report the first couplings of amines with chloro- and bromoindoles bearing a free NH, as well as the first Pd-catalyzed aminations of a 5-halopyrimidine. [reaction: see text]
SN - 1523-7060
UR - https://www.unboundmedicine.com/medline/citation/16119943/Efficient_pd_catalyzed_amination_of_heteroaryl_halides_
DB - PRIME
DP - Unbound Medicine
ER -
