Tags

Type your tag names separated by a space and hit enter

Intensive versus modified conventional control of blood glucose level in medical intensive care patients: a pilot study.
Am J Crit Care. 2005 Sep; 14(5):370-6.AJ

Abstract

BACKGROUND

Critically ill postsurgical patients fare better with intensive control of blood glucose level. The link between glucose control and outcome is less well studied for medical intensive care patients. Whether intensive glucose control requires additional staffing is unclear.

OBJECTIVES

To compare intensive glucose control with modified conventional control in the medical intensive care unit and to assess compliance with glucose targets, incidence of hypoglycemia, and staffing adequacy.

METHODS

Medical intensive care patients who had been receiving mechanical ventilation for less than 24 hours were randomized to intensive or modified conventional protocols for glucose control. Nurses were trained before participating in the study and were interviewed after its completion.

RESULTS

Five subjects were randomized to each protocol. Mean blood glucose levels were 5.8 (SD 1.5) mmol/L (105.3 [SD 26.3] mg/dL) for the intensive group and 9.8 (SD 2.5) mmol/L (177.4 [SD 45.5] mg/dL) for the modified conventional group (P < .001). Fifty percent of glucose levels met target values in the intensive group, and 72% of glucose levels met target values in the modified conventional group (P < .001). Severe hypoglycemia (glucose <2.2 mmol/L [<40 mg/dL]) occurred rarely and without complication. Nurses suggested protocols might be improved by using smaller steps in adjusting insulin dosage and reported that simultaneously caring for more than 1 study subject was taxing.

CONCLUSIONS

Target levels for blood glucose were achieved with both protocols. Severe hypoglycemia was rare and uncomplicated regardless of type of glucose control. Additional staffing may be needed for intensive glucose control.

Authors+Show Affiliations

Department of Medicine, Loma Linda University School of Medicine, CA, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16120888

Citation

Bland, David Kelvin, et al. "Intensive Versus Modified Conventional Control of Blood Glucose Level in Medical Intensive Care Patients: a Pilot Study." American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses, vol. 14, no. 5, 2005, pp. 370-6.
Bland DK, Fankhanel Y, Langford E, et al. Intensive versus modified conventional control of blood glucose level in medical intensive care patients: a pilot study. Am J Crit Care. 2005;14(5):370-6.
Bland, D. K., Fankhanel, Y., Langford, E., Lee, M., Lee, S. W., Maloney, C., Rogers, M., & Zimmerman, G. (2005). Intensive versus modified conventional control of blood glucose level in medical intensive care patients: a pilot study. American Journal of Critical Care : an Official Publication, American Association of Critical-Care Nurses, 14(5), 370-6.
Bland DK, et al. Intensive Versus Modified Conventional Control of Blood Glucose Level in Medical Intensive Care Patients: a Pilot Study. Am J Crit Care. 2005;14(5):370-6. PubMed PMID: 16120888.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intensive versus modified conventional control of blood glucose level in medical intensive care patients: a pilot study. AU - Bland,David Kelvin, AU - Fankhanel,Yvonne, AU - Langford,Eileen, AU - Lee,Martha, AU - Lee,Scott W, AU - Maloney,Colleen, AU - Rogers,Mark, AU - Zimmerman,Grenith, PY - 2005/8/27/pubmed PY - 2005/12/31/medline PY - 2005/8/27/entrez SP - 370 EP - 6 JF - American journal of critical care : an official publication, American Association of Critical-Care Nurses JO - Am J Crit Care VL - 14 IS - 5 N2 - BACKGROUND: Critically ill postsurgical patients fare better with intensive control of blood glucose level. The link between glucose control and outcome is less well studied for medical intensive care patients. Whether intensive glucose control requires additional staffing is unclear. OBJECTIVES: To compare intensive glucose control with modified conventional control in the medical intensive care unit and to assess compliance with glucose targets, incidence of hypoglycemia, and staffing adequacy. METHODS: Medical intensive care patients who had been receiving mechanical ventilation for less than 24 hours were randomized to intensive or modified conventional protocols for glucose control. Nurses were trained before participating in the study and were interviewed after its completion. RESULTS: Five subjects were randomized to each protocol. Mean blood glucose levels were 5.8 (SD 1.5) mmol/L (105.3 [SD 26.3] mg/dL) for the intensive group and 9.8 (SD 2.5) mmol/L (177.4 [SD 45.5] mg/dL) for the modified conventional group (P < .001). Fifty percent of glucose levels met target values in the intensive group, and 72% of glucose levels met target values in the modified conventional group (P < .001). Severe hypoglycemia (glucose <2.2 mmol/L [<40 mg/dL]) occurred rarely and without complication. Nurses suggested protocols might be improved by using smaller steps in adjusting insulin dosage and reported that simultaneously caring for more than 1 study subject was taxing. CONCLUSIONS: Target levels for blood glucose were achieved with both protocols. Severe hypoglycemia was rare and uncomplicated regardless of type of glucose control. Additional staffing may be needed for intensive glucose control. SN - 1062-3264 UR - https://www.unboundmedicine.com/medline/citation/16120888/Intensive_versus_modified_conventional_control_of_blood_glucose_level_in_medical_intensive_care_patients:_a_pilot_study_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=linkout&amp;SEARCH=16120888.ui DB - PRIME DP - Unbound Medicine ER -