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Visceral obesity in men. Associations with glucose tolerance, plasma insulin, and lipoprotein levels.
Diabetes. 1992 Jul; 41(7):826-34.D

Abstract

The relations of regional adipose tissue (AT) distribution measured by computed tomography (CT) to plasma insulin-glucose homeostasis and lipoprotein-lipid levels were studied in 58 obese and 29 lean control men. In the group of obese men, the visceral AT area measured by CT was positively correlated with fasting plasma triglyceride and insulin levels and with glucose and insulin areas under the curves measured during a 75-g oral glucose tolerance test. Visceral AT area was also negatively associated with plasma high-density lipoprotein (HDL) and HDL2 cholesterol levels. The relative accumulation of abdominal fat, estimated by the ratio of abdominal to femoral AT areas obtained by CT, was also a significant correlate of indices of carbohydrate metabolism and was the best univariate correlate of plasma lipoprotein levels. No significant associations were observed between the visceral AT area, the ratio of abdominal to femoral AT areas, and indices of carbohydrate and lipoprotein metabolism in the group of lean men. On the other hand, the subcutaneous abdominal AT area was a significant correlate of the glucose area under the curve in both groups of men, but this association was not independent from the percentage of total body fat. No relationship was observed between the femoral AT area and indices of carbohydrate metabolism in either lean or obese groups. In obese men, however, the femoral AT area was negatively correlated with plasma triglyceride concentration and positively correlated with plasma HDL and HDL2 cholesterol levels.(

ABSTRACT

TRUNCATED AT 250 WORDS)

Authors+Show Affiliations

Physical Activity Sciences Laboratory, Laval University, Ste-Foy, Quebec, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1612197

Citation

Pouliot, M C., et al. "Visceral Obesity in Men. Associations With Glucose Tolerance, Plasma Insulin, and Lipoprotein Levels." Diabetes, vol. 41, no. 7, 1992, pp. 826-34.
Pouliot MC, Després JP, Nadeau A, et al. Visceral obesity in men. Associations with glucose tolerance, plasma insulin, and lipoprotein levels. Diabetes. 1992;41(7):826-34.
Pouliot, M. C., Després, J. P., Nadeau, A., Moorjani, S., Prud'Homme, D., Lupien, P. J., Tremblay, A., & Bouchard, C. (1992). Visceral obesity in men. Associations with glucose tolerance, plasma insulin, and lipoprotein levels. Diabetes, 41(7), 826-34.
Pouliot MC, et al. Visceral Obesity in Men. Associations With Glucose Tolerance, Plasma Insulin, and Lipoprotein Levels. Diabetes. 1992;41(7):826-34. PubMed PMID: 1612197.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Visceral obesity in men. Associations with glucose tolerance, plasma insulin, and lipoprotein levels. AU - Pouliot,M C, AU - Després,J P, AU - Nadeau,A, AU - Moorjani,S, AU - Prud'Homme,D, AU - Lupien,P J, AU - Tremblay,A, AU - Bouchard,C, PY - 1992/7/1/pubmed PY - 1992/7/1/medline PY - 1992/7/1/entrez SP - 826 EP - 34 JF - Diabetes JO - Diabetes VL - 41 IS - 7 N2 - The relations of regional adipose tissue (AT) distribution measured by computed tomography (CT) to plasma insulin-glucose homeostasis and lipoprotein-lipid levels were studied in 58 obese and 29 lean control men. In the group of obese men, the visceral AT area measured by CT was positively correlated with fasting plasma triglyceride and insulin levels and with glucose and insulin areas under the curves measured during a 75-g oral glucose tolerance test. Visceral AT area was also negatively associated with plasma high-density lipoprotein (HDL) and HDL2 cholesterol levels. The relative accumulation of abdominal fat, estimated by the ratio of abdominal to femoral AT areas obtained by CT, was also a significant correlate of indices of carbohydrate metabolism and was the best univariate correlate of plasma lipoprotein levels. No significant associations were observed between the visceral AT area, the ratio of abdominal to femoral AT areas, and indices of carbohydrate and lipoprotein metabolism in the group of lean men. On the other hand, the subcutaneous abdominal AT area was a significant correlate of the glucose area under the curve in both groups of men, but this association was not independent from the percentage of total body fat. No relationship was observed between the femoral AT area and indices of carbohydrate metabolism in either lean or obese groups. In obese men, however, the femoral AT area was negatively correlated with plasma triglyceride concentration and positively correlated with plasma HDL and HDL2 cholesterol levels.(ABSTRACT TRUNCATED AT 250 WORDS) SN - 0012-1797 UR - https://www.unboundmedicine.com/medline/citation/1612197/Visceral_obesity_in_men__Associations_with_glucose_tolerance_plasma_insulin_and_lipoprotein_levels_ L2 - https://diabetes.diabetesjournals.org/lookup/pmidlookup?view=long&pmid=1612197 DB - PRIME DP - Unbound Medicine ER -