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[Histological differential diagnosis of psoriasis vulgaris and seborrheic eczema of the scalp].
Hautarzt. 1979 Sep; 30(9):478-83.H

Abstract

The clinical differential diagnosis between seborrheic dermatitis and psoriasis vulgaris of the scalp can be difficult. We, therefore, tried to elaborate histopathological criteria for a differentiation of the two dermatoses. Forty excisional biopsies were analysed without knowing the clinical diagnosis. The histopathological substrate within the epidermis is characterized in psoriasis by dermatitis-like and in seborrheic dermatitis by psoriasis-like alterations. Therefore, in some cases a definite histopathological diagnosis could not be made. Strong criteria favouring psoriasis are: moderate condensed hyperkeratosis with alternating parakeratosis, PAS-reactive serum inclusions and Munro abscesses within the horny layer, spongiform pustles and neutrophilic leukocytes within the epidermis. Strong criteria for seborrheic dermatitis are: irregular acanthosis with relatively thin condensed orthoor parakeratotic horny layer, spongiosis and spongiotic vesicles, exocytosis of lymphocytes and the lack of any hard criterias for psoriasis. The results may suggest that seborrheic dermatitis of the scalp may transform into psoriasis in patients with a genetical disposition ("psoriatic diathesis", "latent psoriasis") via a Köbner reaction. The existence of the seborrheic dermatitis (Morbus Unna) is not doubted by these investigations.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

161301

Citation

Braun-Falco, O, et al. "[Histological Differential Diagnosis of Psoriasis Vulgaris and Seborrheic Eczema of the Scalp]." Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete, vol. 30, no. 9, 1979, pp. 478-83.
Braun-Falco O, Heilgemeir GP, Lincke-Plewig H. [Histological differential diagnosis of psoriasis vulgaris and seborrheic eczema of the scalp]. Hautarzt. 1979;30(9):478-83.
Braun-Falco, O., Heilgemeir, G. P., & Lincke-Plewig, H. (1979). [Histological differential diagnosis of psoriasis vulgaris and seborrheic eczema of the scalp]. Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete, 30(9), 478-83.
Braun-Falco O, Heilgemeir GP, Lincke-Plewig H. [Histological Differential Diagnosis of Psoriasis Vulgaris and Seborrheic Eczema of the Scalp]. Hautarzt. 1979;30(9):478-83. PubMed PMID: 161301.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Histological differential diagnosis of psoriasis vulgaris and seborrheic eczema of the scalp]. AU - Braun-Falco,O, AU - Heilgemeir,G P, AU - Lincke-Plewig,H, PY - 1979/9/1/pubmed PY - 1979/9/1/medline PY - 1979/9/1/entrez SP - 478 EP - 83 JF - Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete JO - Hautarzt VL - 30 IS - 9 N2 - The clinical differential diagnosis between seborrheic dermatitis and psoriasis vulgaris of the scalp can be difficult. We, therefore, tried to elaborate histopathological criteria for a differentiation of the two dermatoses. Forty excisional biopsies were analysed without knowing the clinical diagnosis. The histopathological substrate within the epidermis is characterized in psoriasis by dermatitis-like and in seborrheic dermatitis by psoriasis-like alterations. Therefore, in some cases a definite histopathological diagnosis could not be made. Strong criteria favouring psoriasis are: moderate condensed hyperkeratosis with alternating parakeratosis, PAS-reactive serum inclusions and Munro abscesses within the horny layer, spongiform pustles and neutrophilic leukocytes within the epidermis. Strong criteria for seborrheic dermatitis are: irregular acanthosis with relatively thin condensed orthoor parakeratotic horny layer, spongiosis and spongiotic vesicles, exocytosis of lymphocytes and the lack of any hard criterias for psoriasis. The results may suggest that seborrheic dermatitis of the scalp may transform into psoriasis in patients with a genetical disposition ("psoriatic diathesis", "latent psoriasis") via a Köbner reaction. The existence of the seborrheic dermatitis (Morbus Unna) is not doubted by these investigations. SN - 0017-8470 UR - https://www.unboundmedicine.com/medline/citation/161301/[Histological_differential_diagnosis_of_psoriasis_vulgaris_and_seborrheic_eczema_of_the_scalp]_ L2 - https://www.diseaseinfosearch.org/result/9652 DB - PRIME DP - Unbound Medicine ER -