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Fluid, electrolyte, and renal indices of hydration during 11 days of controlled caffeine consumption.
Int J Sport Nutr Exerc Metab 2005; 15(3):252-65IJ

Abstract

This investigation determined if 3 levels of controlled caffeine consumption affected fluid-electrolyte balance and renal function differently. Healthy males (mean +/- standard deviation; age, 21.6 +/- 3.3 y) consumed 3 mg caffeine . kg(-1) . d(-1). on days 1 to 6 (equilibration phase). On days 7 to 11 (treatment phase), subjects consumed either 0 mg (C0; placebo; n= 20), 3 mg (C3; n = 20), or 6 mg (C6; n = 19) caffeine . kg(-1) . d(-1) in capsules, with no other dietary caffeine intake. The following variables were unaffected (P > 0.05) by different caffeine doses on days 1, 3, 6, 9, and 11 and were within normal clinical ranges: body mass, urine osmolality, urine specific gravity, urine color, 24-h urine volume, 24-h Na+ and K+ excretion, 24-h creatinine, blood urea nitrogen, serum Na+ and K+, serum osmolality, hematocrit, and total plasma protein. Therefore, C0, C3, and C6 exhibited no evidence of hypohydration. These findings question the widely accepted notion that caffeine consumption acts chronically as a diuretic.

Authors+Show Affiliations

University of Connecticut, Human Performance Laboratory, Storrs, CT 06269, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

16131696

Citation

Armstrong, Lawrence E., et al. "Fluid, Electrolyte, and Renal Indices of Hydration During 11 Days of Controlled Caffeine Consumption." International Journal of Sport Nutrition and Exercise Metabolism, vol. 15, no. 3, 2005, pp. 252-65.
Armstrong LE, Pumerantz AC, Roti MW, et al. Fluid, electrolyte, and renal indices of hydration during 11 days of controlled caffeine consumption. Int J Sport Nutr Exerc Metab. 2005;15(3):252-65.
Armstrong, L. E., Pumerantz, A. C., Roti, M. W., Judelson, D. A., Watson, G., Dias, J. C., ... Kellogg, M. (2005). Fluid, electrolyte, and renal indices of hydration during 11 days of controlled caffeine consumption. International Journal of Sport Nutrition and Exercise Metabolism, 15(3), pp. 252-65.
Armstrong LE, et al. Fluid, Electrolyte, and Renal Indices of Hydration During 11 Days of Controlled Caffeine Consumption. Int J Sport Nutr Exerc Metab. 2005;15(3):252-65. PubMed PMID: 16131696.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fluid, electrolyte, and renal indices of hydration during 11 days of controlled caffeine consumption. AU - Armstrong,Lawrence E, AU - Pumerantz,Amy C, AU - Roti,Melissa W, AU - Judelson,Daniel A, AU - Watson,Greig, AU - Dias,Joao C, AU - Sokmen,Bulent, AU - Casa,Douglas J, AU - Maresh,Carl M, AU - Lieberman,Harris, AU - Kellogg,Mark, PY - 2005/9/1/pubmed PY - 2005/10/4/medline PY - 2005/9/1/entrez SP - 252 EP - 65 JF - International journal of sport nutrition and exercise metabolism JO - Int J Sport Nutr Exerc Metab VL - 15 IS - 3 N2 - This investigation determined if 3 levels of controlled caffeine consumption affected fluid-electrolyte balance and renal function differently. Healthy males (mean +/- standard deviation; age, 21.6 +/- 3.3 y) consumed 3 mg caffeine . kg(-1) . d(-1). on days 1 to 6 (equilibration phase). On days 7 to 11 (treatment phase), subjects consumed either 0 mg (C0; placebo; n= 20), 3 mg (C3; n = 20), or 6 mg (C6; n = 19) caffeine . kg(-1) . d(-1) in capsules, with no other dietary caffeine intake. The following variables were unaffected (P > 0.05) by different caffeine doses on days 1, 3, 6, 9, and 11 and were within normal clinical ranges: body mass, urine osmolality, urine specific gravity, urine color, 24-h urine volume, 24-h Na+ and K+ excretion, 24-h creatinine, blood urea nitrogen, serum Na+ and K+, serum osmolality, hematocrit, and total plasma protein. Therefore, C0, C3, and C6 exhibited no evidence of hypohydration. These findings question the widely accepted notion that caffeine consumption acts chronically as a diuretic. SN - 1526-484X UR - https://www.unboundmedicine.com/medline/citation/16131696/Fluid_electrolyte_and_renal_indices_of_hydration_during_11_days_of_controlled_caffeine_consumption_ L2 - https://medlineplus.gov/dehydration.html DB - PRIME DP - Unbound Medicine ER -