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Breast cancer and dietary factors in Taiwanese women.

Abstract

OBJECTIVES

To examine the effect of the consumption of dietary factors on the risk of breast cancer in a case-control study in Taiwan.

METHODS

Two-hundred-and-fifty cases and 219 age-matched controls between the ages of 25 and 74 were interviewed in person between 1996 and 1999. Usual consumption of dietary habits including 100 foods was assessed using a food frequency questionnaire and a nutrient database developed and validated in Taiwanese populations.

RESULTS

Cases consumed significantly more fat than controls. Cases also consumed statistically significant less supplements such as vitamins and mineral than controls. Food group analyses showed that highest quartile of beef and pork intake significantly increased risk in younger women (OR = 2.5, 95% CI = 1.0-6.0) and all women (OR = 2.5, 95% CI = 1.1-3.3). The age- education- and total calorie-adjusted odds ratio (OR) of breast cancer risk comparing the highest and second highest quartile of fat intake to the lowest quartile was 5.1, 95% confidence interval (CI): 2.1-13 and 3.5, 95% CI: 1.4-8.7 among those younger cases (< or =40). A multiple regression model indicates a protective effect of supplements (OR: 0.40, 95% CI: 0.3-07) and a harmful effect of dietary fat (OR: 2.6, 95% CI: 1.4-5.0) for the highest versus lowest quartile in all women.

CONCLUSIONS

Our results indicate a strong protective effect of dietary supplements and a harmful effect of dietary fats on the risk of breast cancer among women in Taiwan. These findings should be confirmed in future follow-up studies. Specific amount of dietary supplements and dietary fats should be quantified for a more accurate evaluation on the risk for breast cancer in this population.

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  • Authors+Show Affiliations

    ,

    Department of Epidemiology and Biostatistics, University of California at San Francisco, MU 420 West, San Francisco, CA 94143-0560, USA. mmlee@itsa.ucsf.edu

    , , , ,

    Source

    Cancer causes & control : CCC 16:8 2005 Oct pg 929-37

    MeSH

    Adult
    Age of Onset
    Aged
    Breast Neoplasms
    Case-Control Studies
    Diet
    Dietary Fats
    Dietary Supplements
    Energy Intake
    Female
    Humans
    Interviews as Topic
    Logistic Models
    Middle Aged
    Motor Activity
    Multivariate Analysis
    Nutrition Assessment
    Odds Ratio
    Risk Factors
    Taiwan

    Pub Type(s)

    Controlled Clinical Trial
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    16132802

    Citation

    Lee, Marion M., et al. "Breast Cancer and Dietary Factors in Taiwanese Women." Cancer Causes & Control : CCC, vol. 16, no. 8, 2005, pp. 929-37.
    Lee MM, Chang IY, Horng CF, et al. Breast cancer and dietary factors in Taiwanese women. Cancer Causes Control. 2005;16(8):929-37.
    Lee, M. M., Chang, I. Y., Horng, C. F., Chang, J. S., Cheng, S. H., & Huang, A. (2005). Breast cancer and dietary factors in Taiwanese women. Cancer Causes & Control : CCC, 16(8), pp. 929-37.
    Lee MM, et al. Breast Cancer and Dietary Factors in Taiwanese Women. Cancer Causes Control. 2005;16(8):929-37. PubMed PMID: 16132802.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Breast cancer and dietary factors in Taiwanese women. AU - Lee,Marion M, AU - Chang,Ilona Yuan Hui, AU - Horng,Cheng Fang, AU - Chang,Jeffrey S, AU - Cheng,Skye Hongiun, AU - Huang,Andrew, PY - 2004/10/07/received PY - 2005/04/05/accepted PY - 2005/9/1/pubmed PY - 2006/1/6/medline PY - 2005/9/1/entrez SP - 929 EP - 37 JF - Cancer causes & control : CCC JO - Cancer Causes Control VL - 16 IS - 8 N2 - OBJECTIVES: To examine the effect of the consumption of dietary factors on the risk of breast cancer in a case-control study in Taiwan. METHODS: Two-hundred-and-fifty cases and 219 age-matched controls between the ages of 25 and 74 were interviewed in person between 1996 and 1999. Usual consumption of dietary habits including 100 foods was assessed using a food frequency questionnaire and a nutrient database developed and validated in Taiwanese populations. RESULTS: Cases consumed significantly more fat than controls. Cases also consumed statistically significant less supplements such as vitamins and mineral than controls. Food group analyses showed that highest quartile of beef and pork intake significantly increased risk in younger women (OR = 2.5, 95% CI = 1.0-6.0) and all women (OR = 2.5, 95% CI = 1.1-3.3). The age- education- and total calorie-adjusted odds ratio (OR) of breast cancer risk comparing the highest and second highest quartile of fat intake to the lowest quartile was 5.1, 95% confidence interval (CI): 2.1-13 and 3.5, 95% CI: 1.4-8.7 among those younger cases (< or =40). A multiple regression model indicates a protective effect of supplements (OR: 0.40, 95% CI: 0.3-07) and a harmful effect of dietary fat (OR: 2.6, 95% CI: 1.4-5.0) for the highest versus lowest quartile in all women. CONCLUSIONS: Our results indicate a strong protective effect of dietary supplements and a harmful effect of dietary fats on the risk of breast cancer among women in Taiwan. These findings should be confirmed in future follow-up studies. Specific amount of dietary supplements and dietary fats should be quantified for a more accurate evaluation on the risk for breast cancer in this population. SN - 0957-5243 UR - https://www.unboundmedicine.com/medline/citation/16132802/Breast_cancer_and_dietary_factors_in_Taiwanese_women_ L2 - https://doi.org/10.1007/s10552-005-4932-9 DB - PRIME DP - Unbound Medicine ER -