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Is type 1 diabetes a disease of the gut immune system triggered by cow's milk insulin?

Abstract

The role of the gut immune system in the development of autoimmune type 1 diabetes is evaluated in this review with special emphasis in the hypothesis suggesting that dietary cow's milk insulin could trigger beta-cell autoimmunity when the mechanisms of oral tolerance are disturbed.

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  • Publisher Full Text
  • Authors+Show Affiliations

    Department of Molecular and Clinical Medicine, Faculty of Health Sciences, University of Linköping, 58185, Sweden.

    Source

    MeSH

    Animals
    Autoimmune Diseases
    Cattle
    Diabetes Mellitus, Type 1
    Digestive System
    Humans
    Infant
    Infant Food
    Infant Nutritional Physiological Phenomena
    Infant, Newborn
    Milk Proteins

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    16137120

    Citation

    TY - JOUR T1 - Is type 1 diabetes a disease of the gut immune system triggered by cow's milk insulin? A1 - Vaarala,Outi, PY - 2005/9/3/pubmed PY - 2005/12/24/medline PY - 2005/9/3/entrez SP - 151 EP - 6 JF - Advances in experimental medicine and biology JO - Adv. Exp. Med. Biol. VL - 569 N2 - The role of the gut immune system in the development of autoimmune type 1 diabetes is evaluated in this review with special emphasis in the hypothesis suggesting that dietary cow's milk insulin could trigger beta-cell autoimmunity when the mechanisms of oral tolerance are disturbed. SN - 0065-2598 UR - https://www.unboundmedicine.com/medline/citation/16137120/full_citation L2 - https://dx.doi.org/10.1007/1-4020-3535-7_22 ER -