Tags

Type your tag names separated by a space and hit enter

Public awareness about risk factors could pose problems for case-control studies: the example of sunbed use and cutaneous melanoma.

Abstract

In a large case-control study we found no association between sunbed use and melanoma risk, but indications for potential recall and recruitment biases made the interpretation of the results difficult. Associations with skin phototype (adj OR for skin type I vs. IV: (2.6, 95% CI 1.5-4.8)), hair colour (adj OR red/blond vs. brown/black 2.0 (95% CI 1.4-2.8)) and number of naevi on both arms (OR>10 vs. 10 3.13 (95% CI: 2.47; 3.97)) were comparable to previous studies, but negative associations were found between sun exposure and melanoma risk (adj. OR 0.87 (95% CI: 0.65-1.18)) and in cases between sun exposure and naevus count. These observations led us to speculate that cases may have underreported their sun exposure and, most likely, their sunbed exposure. High percentages of sunbed use among controls indicated possible recruitment bias: eligible controls who were sunbed users were probably more likely to accept the invitation to participate than non-users, possibly due to a feeling of 'guilt' or 'worry' about their habits. Such selective participation may have strongly influenced the risk estimates of sunbed use in our study.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Public Health, Erasmus MC, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands. e.devries@erasmusmc.nl

    , , , , , ,

    Source

    MeSH

    Adult
    Attitude to Health
    Awareness
    Case-Control Studies
    Female
    Humans
    Male
    Melanoma
    Neoplasms, Radiation-Induced
    Nevus
    Risk Factors
    Self Disclosure
    Skin Neoplasms
    Sunlight
    Ultraviolet Rays

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    16139499

    Citation

    de Vries, E, et al. "Public Awareness About Risk Factors Could Pose Problems for Case-control Studies: the Example of Sunbed Use and Cutaneous Melanoma." European Journal of Cancer (Oxford, England : 1990), vol. 41, no. 14, 2005, pp. 2150-4.
    de Vries E, Boniol M, Severi G, et al. Public awareness about risk factors could pose problems for case-control studies: the example of sunbed use and cutaneous melanoma. Eur J Cancer. 2005;41(14):2150-4.
    de Vries, E., Boniol, M., Severi, G., Eggermont, A. M., Autier, P., Bataille, V., ... Coebergh, J. W. (2005). Public awareness about risk factors could pose problems for case-control studies: the example of sunbed use and cutaneous melanoma. European Journal of Cancer (Oxford, England : 1990), 41(14), pp. 2150-4.
    de Vries E, et al. Public Awareness About Risk Factors Could Pose Problems for Case-control Studies: the Example of Sunbed Use and Cutaneous Melanoma. Eur J Cancer. 2005;41(14):2150-4. PubMed PMID: 16139499.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Public awareness about risk factors could pose problems for case-control studies: the example of sunbed use and cutaneous melanoma. AU - de Vries,E, AU - Boniol,M, AU - Severi,G, AU - Eggermont,A M M, AU - Autier,P, AU - Bataille,V, AU - Doré,J F, AU - Coebergh,J W W, PY - 2005/04/19/received PY - 2005/04/27/accepted PY - 2005/9/6/pubmed PY - 2005/12/13/medline PY - 2005/9/6/entrez SP - 2150 EP - 4 JF - European journal of cancer (Oxford, England : 1990) JO - Eur. J. Cancer VL - 41 IS - 14 N2 - In a large case-control study we found no association between sunbed use and melanoma risk, but indications for potential recall and recruitment biases made the interpretation of the results difficult. Associations with skin phototype (adj OR for skin type I vs. IV: (2.6, 95% CI 1.5-4.8)), hair colour (adj OR red/blond vs. brown/black 2.0 (95% CI 1.4-2.8)) and number of naevi on both arms (OR>10 vs. 10 3.13 (95% CI: 2.47; 3.97)) were comparable to previous studies, but negative associations were found between sun exposure and melanoma risk (adj. OR 0.87 (95% CI: 0.65-1.18)) and in cases between sun exposure and naevus count. These observations led us to speculate that cases may have underreported their sun exposure and, most likely, their sunbed exposure. High percentages of sunbed use among controls indicated possible recruitment bias: eligible controls who were sunbed users were probably more likely to accept the invitation to participate than non-users, possibly due to a feeling of 'guilt' or 'worry' about their habits. Such selective participation may have strongly influenced the risk estimates of sunbed use in our study. SN - 0959-8049 UR - https://www.unboundmedicine.com/medline/citation/16139499/Public_awareness_about_risk_factors_could_pose_problems_for_case_control_studies:_the_example_of_sunbed_use_and_cutaneous_melanoma_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0959-8049(05)00543-5 DB - PRIME DP - Unbound Medicine ER -