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[Related inflammation markers among different types of coronary heart disease].
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2004 Apr; 29(2):227-9.ZN

Abstract

OBJECTIVE

To study the relationship between levels of activity of NF-kappaB p65, plasma soluble inter-cellular adhesion molecule-1, C-reactive protein on plaque stability, and different types of coronary heart disease.

METHODS

We measured the levels of plasma soluble inter-cellular adhesion molecule-1 and C-reactive protein by enzyme-linked immunosorbant assay and the activity of NF-kappaB p65 in peripheral blood lymocytes immunohistochemically.

RESULTS

Compared with the stable angina and the control group, the baseline activity of NF-kappaB p65, sICAM-1 and C-reactive protein was significantly elevated in the acute myocardial infarction and the unstable angina (P <0.01). After 3 month follow-up, the levels of activity of NF-kappaB p65 and sICAM-1 were unchanged (P > 0.05). In all groups, C-reactive proteins were lowered at the review (P <0.01).

CONCLUSION

The levels of activity of NF-kappaB p65, sICAM-1 and C-reactive protein are related to the plaque stability among different types of coronary heart disease. NF-kappaB p65, and sICAM-1 are not affected by the acute event. These plasma markers may be important risk factors for the development of the acute coronary syndrome.

Authors+Show Affiliations

Department of Gerontology, Xiangya Hospital, Central South University, Changsha, China. XLYL@medmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

16145923

Citation

Luo, Ying, et al. "[Related Inflammation Markers Among Different Types of Coronary Heart Disease]." Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences, vol. 29, no. 2, 2004, pp. 227-9.
Luo Y, Xie XM, Liu HX. [Related inflammation markers among different types of coronary heart disease]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2004;29(2):227-9.
Luo, Y., Xie, X. M., & Liu, H. X. (2004). [Related inflammation markers among different types of coronary heart disease]. Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences, 29(2), 227-9.
Luo Y, Xie XM, Liu HX. [Related Inflammation Markers Among Different Types of Coronary Heart Disease]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2004;29(2):227-9. PubMed PMID: 16145923.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Related inflammation markers among different types of coronary heart disease]. AU - Luo,Ying, AU - Xie,Xiu-Mei, AU - Liu,Hui-Xia, PY - 2005/9/9/pubmed PY - 2007/3/17/medline PY - 2005/9/9/entrez SP - 227 EP - 9 JF - Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences JO - Zhong Nan Da Xue Xue Bao Yi Xue Ban VL - 29 IS - 2 N2 - OBJECTIVE: To study the relationship between levels of activity of NF-kappaB p65, plasma soluble inter-cellular adhesion molecule-1, C-reactive protein on plaque stability, and different types of coronary heart disease. METHODS: We measured the levels of plasma soluble inter-cellular adhesion molecule-1 and C-reactive protein by enzyme-linked immunosorbant assay and the activity of NF-kappaB p65 in peripheral blood lymocytes immunohistochemically. RESULTS: Compared with the stable angina and the control group, the baseline activity of NF-kappaB p65, sICAM-1 and C-reactive protein was significantly elevated in the acute myocardial infarction and the unstable angina (P <0.01). After 3 month follow-up, the levels of activity of NF-kappaB p65 and sICAM-1 were unchanged (P > 0.05). In all groups, C-reactive proteins were lowered at the review (P <0.01). CONCLUSION: The levels of activity of NF-kappaB p65, sICAM-1 and C-reactive protein are related to the plaque stability among different types of coronary heart disease. NF-kappaB p65, and sICAM-1 are not affected by the acute event. These plasma markers may be important risk factors for the development of the acute coronary syndrome. SN - 1672-7347 UR - https://www.unboundmedicine.com/medline/citation/16145923/[Related_inflammation_markers_among_different_types_of_coronary_heart_disease]_ L2 - http://xbyxb.csu.edu.cn/xbwk/fileup/PDF/200404227.pdf DB - PRIME DP - Unbound Medicine ER -