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Lipid and apolipoproteins (ApoAI, ApoB, Apo CIII, ApoE) disturbance in hemodialysis (HD) and renal transplant (Tx) patients.

Abstract

The aim of the study was to evaluate the serum lipid and apolipoprotein profiles among patients after renal transplantation (Tx) and to compare them with the profiles obtained for permanently hemodialysed patients (HD). The investigations were performed at 15 Tx, 40 HD patients and the control group of 40 healthy subjects. There were significantly increased TG, ApoAIII, ApoE, TC/ HDL-C, ApoCIII non B, ApoCIII:B and decreased HDL-C, ApoAI, HDL-C/ApoAI, ApoAI/ApoCIII, ApoB/ApoCIII ratios comparing HD patients to the control group. There were increased TG, ApoCIII, ApoCIII non B, ApoB/ApoCIII ratios and decreased ApoAI/ApoCIII ratios in Tx patients as compared to the control subjects. Moreover, there were significantly higher HDL, ApoAI, HDL/ApoAI, ApoCIII non B and lower ApoE, ApoE/ApoB, ApoCIII:B ratios in Tx patients as compared to these of HD patients. Significant inverse correlation of the time which passed from executed Tx and ApoCIII:B ratio (r = -0.67; p < 0.01) at renal transplant patients were observed, which means the diminished risk of development of atherosclerosis.

Authors+Show Affiliations

Chair and Department of General Surgery and Transplantology, Skubiszewski Medical University of Lublin.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16146031

Citation

Janicki, Krzysztof, et al. "Lipid and Apolipoproteins (ApoAI, ApoB, Apo CIII, ApoE) Disturbance in Hemodialysis (HD) and Renal Transplant (Tx) Patients." Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, vol. 59, no. 1, 2004, pp. 459-66.
Janicki K, Solski J, Janicka L, et al. Lipid and apolipoproteins (ApoAI, ApoB, Apo CIII, ApoE) disturbance in hemodialysis (HD) and renal transplant (Tx) patients. Ann Univ Mariae Curie Sklodowska Med. 2004;59(1):459-66.
Janicki, K., Solski, J., Janicka, L., Kimak, E., Bednarek-Skublewska, A., Stettner, S., & Molas, G. (2004). Lipid and apolipoproteins (ApoAI, ApoB, Apo CIII, ApoE) disturbance in hemodialysis (HD) and renal transplant (Tx) patients. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 59(1), pp. 459-66.
Janicki K, et al. Lipid and Apolipoproteins (ApoAI, ApoB, Apo CIII, ApoE) Disturbance in Hemodialysis (HD) and Renal Transplant (Tx) Patients. Ann Univ Mariae Curie Sklodowska Med. 2004;59(1):459-66. PubMed PMID: 16146031.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lipid and apolipoproteins (ApoAI, ApoB, Apo CIII, ApoE) disturbance in hemodialysis (HD) and renal transplant (Tx) patients. AU - Janicki,Krzysztof, AU - Solski,Janusz, AU - Janicka,Lucyna, AU - Kimak,Elzbieta, AU - Bednarek-Skublewska,Anna, AU - Stettner,Seweryn, AU - Molas,Grzegorz, PY - 2005/9/9/pubmed PY - 2005/10/12/medline PY - 2005/9/9/entrez SP - 459 EP - 66 JF - Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina JO - Ann Univ Mariae Curie Sklodowska Med VL - 59 IS - 1 N2 - The aim of the study was to evaluate the serum lipid and apolipoprotein profiles among patients after renal transplantation (Tx) and to compare them with the profiles obtained for permanently hemodialysed patients (HD). The investigations were performed at 15 Tx, 40 HD patients and the control group of 40 healthy subjects. There were significantly increased TG, ApoAIII, ApoE, TC/ HDL-C, ApoCIII non B, ApoCIII:B and decreased HDL-C, ApoAI, HDL-C/ApoAI, ApoAI/ApoCIII, ApoB/ApoCIII ratios comparing HD patients to the control group. There were increased TG, ApoCIII, ApoCIII non B, ApoB/ApoCIII ratios and decreased ApoAI/ApoCIII ratios in Tx patients as compared to the control subjects. Moreover, there were significantly higher HDL, ApoAI, HDL/ApoAI, ApoCIII non B and lower ApoE, ApoE/ApoB, ApoCIII:B ratios in Tx patients as compared to these of HD patients. Significant inverse correlation of the time which passed from executed Tx and ApoCIII:B ratio (r = -0.67; p < 0.01) at renal transplant patients were observed, which means the diminished risk of development of atherosclerosis. SN - 0066-2240 UR - https://www.unboundmedicine.com/medline/citation/16146031/Lipid_and_apolipoproteins__ApoAI_ApoB_Apo_CIII_ApoE__disturbance_in_hemodialysis__HD__and_renal_transplant__Tx__patients_ L2 - https://medlineplus.gov/kidneytransplantation.html DB - PRIME DP - Unbound Medicine ER -