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Chiral binaphthyl-derived amine-thiourea organocatalyst-promoted asymmetric Morita-Baylis-Hillman reaction.
Org Lett. 2005 Sep 15; 7(19):4293-6.OL

Abstract

[reaction: see text] A new bifunctional binaphthyl-derived amine thiourea organocatalyst has been developed to promote enantioselective Morita-Baylis-Hillman reaction of cyclohexenone with a wide range of aldehydes. The process, catalyzed by the amine thiourea, affords synthetically valuable chiral allylic alcohol building blocks in high yields and high enantioselectivities.

Authors+Show Affiliations

Wang J
Department of Chemistry, University of New Mexico, Albuquerque, New Mexico 87131-0001, USA.
Li H
No affiliation info available
Yu X
No affiliation info available
Zu L
No affiliation info available
Wang W
No affiliation info available

MeSH

AldehydesAminesCatalysisChemistry, OrganicMolecular StructureNaphthalenesOrganic Chemistry PhenomenaStereoisomerismThiourea

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16146410

Citation

Wang, Jian, et al. "Chiral Binaphthyl-derived Amine-thiourea Organocatalyst-promoted Asymmetric Morita-Baylis-Hillman Reaction." Organic Letters, vol. 7, no. 19, 2005, pp. 4293-6.
Wang J, Li H, Yu X, et al. Chiral binaphthyl-derived amine-thiourea organocatalyst-promoted asymmetric Morita-Baylis-Hillman reaction. Org Lett. 2005;7(19):4293-6.
Wang, J., Li, H., Yu, X., Zu, L., & Wang, W. (2005). Chiral binaphthyl-derived amine-thiourea organocatalyst-promoted asymmetric Morita-Baylis-Hillman reaction. Organic Letters, 7(19), 4293-6.
Wang J, et al. Chiral Binaphthyl-derived Amine-thiourea Organocatalyst-promoted Asymmetric Morita-Baylis-Hillman Reaction. Org Lett. 2005 Sep 15;7(19):4293-6. PubMed PMID: 16146410.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chiral binaphthyl-derived amine-thiourea organocatalyst-promoted asymmetric Morita-Baylis-Hillman reaction. AU - Wang,Jian, AU - Li,Hao, AU - Yu,Xinhong, AU - Zu,Liansuo, AU - Wang,Wei, PY - 2005/9/9/pubmed PY - 2006/8/5/medline PY - 2005/9/9/entrez SP - 4293 EP - 6 JF - Organic letters JO - Org Lett VL - 7 IS - 19 N2 - [reaction: see text] A new bifunctional binaphthyl-derived amine thiourea organocatalyst has been developed to promote enantioselective Morita-Baylis-Hillman reaction of cyclohexenone with a wide range of aldehydes. The process, catalyzed by the amine thiourea, affords synthetically valuable chiral allylic alcohol building blocks in high yields and high enantioselectivities. SN - 1523-7060 UR - https://www.unboundmedicine.com/medline/citation/16146410/Chiral_binaphthyl_derived_amine_thiourea_organocatalyst_promoted_asymmetric_Morita_Baylis_Hillman_reaction_ DB - PRIME DP - Unbound Medicine ER -